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The nervous system is an organ system containing a network of specialized cells called neurons that coordinate the actions of an animal and transmit signals between different parts of its body. In most animals the nervous system consists of two parts, central and peripheral. The central nervous system contains the brain and spinal cord.
Scientists uncover mechanism behind 'tubulin code'

Scientists uncover mechanism behind 'tubulin code'

Driving down the highway, you encounter ever-changing signs -- speed limits, exits, food and gas options. Seeing these roadside markers may cause you to slow down, change lanes or start thinking about lunch. In a similar way, cellular structures called microtubules are tagged with a variety of chemical markers that can influence cell functions. [More]
Childhood cancer survivors more likely to be obese than healthy peers

Childhood cancer survivors more likely to be obese than healthy peers

Childhood cancer survivors - especially those whose treatment included brain irradiation or chemotherapy with glucocorticoids - are 14 percent more likely to be obese than their healthy peers. [More]
Brain protein plays key role in controlling binge drinking

Brain protein plays key role in controlling binge drinking

Scientists at The Scripps Research Institute have discovered that a brain protein has a key role in controlling binge drinking in animal models. They found that deleting the gene for this protein in mice ramped up alcohol consumption and prevented the brain from signaling the rewarding properties of alcohol. [More]
TSRI scientists map out protein structure involved in cellular function, nervous system development

TSRI scientists map out protein structure involved in cellular function, nervous system development

Scientists from The Scripps Research Institute, working closely with researchers at the National Institutes of Health, have mapped out the structure of an important protein involved in cellular function and nervous system development. [More]
Immune system plays surprising role in the progression of Rett syndrome

Immune system plays surprising role in the progression of Rett syndrome

New research by investigators at the University of Massachusetts Medical School suggests the immune system plays an unsuspected and surprising role in the progression of Rett syndrome, a severe neurological disorder affecting children. Immune cells known as macrophages are unable to perform their normal function and are instead amplifying the disease. [More]
Panacea Pharmaceuticals selects Goodwin to complete novel vaccine Fill / Finish project

Panacea Pharmaceuticals selects Goodwin to complete novel vaccine Fill / Finish project

Goodwin Biotechnology, Inc., a biological Contract Development and Manufacturing Organization that specializes in bioprocess development and GMP manufacturing of biopharmaceuticals utilizing Mammalian Cell Culture expression systems and Bioconjugation technologies, was selected by Panacea Pharmaceuticals, Inc. to complete a novel Fill / Finish project, as well as Quality Control release and stability testing for a therapeutic, nanoparticle cancer vaccine based on the Human Aspartyl (Asparaginyl) β-Hydroxylase (HAAH) tumor-specific protein to support Phase I clinical trials in patients with various solid tumor cancers. [More]
Workplace mindfulness-based intervention reduces stress levels and risk of burnout

Workplace mindfulness-based intervention reduces stress levels and risk of burnout

A study by researchers at The Ohio State University Wexner Medical Center found that a workplace mindfulness-based intervention reduced stress levels of employees exposed to a highly stressful occupational environment. [More]
Small ion pump gives new hope for severe nerve pain sufferers

Small ion pump gives new hope for severe nerve pain sufferers

A small ion pump in organic electronics is giving new hope to people suffering from severe nerve pain. Researchers at Swedish Linköping University and the Karolinska Institute are the first in the world with technology that can stop pain impulses in living, freely moving rats using the body's own pain relief signals. [More]
Global survey finds gap in physicians' understanding on impact of lupus on patients' lives

Global survey finds gap in physicians' understanding on impact of lupus on patients' lives

As many people in the lupus community prepare to come together in support of World Lupus Day (May 10), a global survey shows that systemic lupus erythematosus (SLE) patients have difficulty describing their symptoms to their physicians, which leads to a gap in physicians understanding the full impact the illness has on patients' lives. [More]
Gene therapy is key to addressing Sanfilippo Syndrome, say Ohio scientists and clinicians

Gene therapy is key to addressing Sanfilippo Syndrome, say Ohio scientists and clinicians

Gene therapy is the delivery of DNA into a patient's cells to replace faulty or missing genes—or adds new genes—in an attempt to cure cancer or make changes so the body is better able to fight off disease. Scientists and clinicians have identified a number of different ways to do this, in an effort to correct malfunctioning or mutated genes. Many gene therapy clinical trials are ongoing to assess the safety and potential benefits in patients with rare diseases. [More]
Obesity and depression play role in excessive daytime sleepiness

Obesity and depression play role in excessive daytime sleepiness

Obesity and depression -- not only lack of sleep -- are underlying causes for regular drowsiness, according to Penn State College of Medicine researchers. They say these findings could lead to more personalized sleep medicine for those with excessive daytime sleepiness (EDS). [More]
New compound offers longer lasting painkilling effects

New compound offers longer lasting painkilling effects

Medications have long been used to treat pain caused by injury or chronic conditions. Unfortunately, most are short-term fixes or cause side effects that limit their use. Researchers at the University of Missouri have discovered a new compound that offers longer lasting painkilling effects, and shows promise as an alternative to current anesthetics. [More]
Study analyzes outcomes of brain metastases patients following stereotactic radiosurgery

Study analyzes outcomes of brain metastases patients following stereotactic radiosurgery

Winner of the Leksell Radiosurgery Award, Deborah C. Marshall, recently presented her research, Survival Patterns of Patients with Cerebral Metastases after Multiple Rounds of Stereotactic Radiosurgery (SRS), at the 2015 American Association of Neurological Surgeons Annual Scientific Meeting. [More]
Quantitative phosphoproteomic approach to identify targeted cancer therapy

Quantitative phosphoproteomic approach to identify targeted cancer therapy

Winner of the Louise Eisenhardt Traveling Scholarship Award, Teresa Purzner, MD, presented her research, Quantitative Phosphoproteomics for Targeted Cancer Therapy. [More]
New MGH-developed technology may extend benefits of MRI in patients with implanted devices

New MGH-developed technology may extend benefits of MRI in patients with implanted devices

New technology developed at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital may extend the benefits of magnetic resonance imaging (MRI) to many patients whose access to MRI is currently limited. [More]
Proteomics helps identify previously unrecognized proteins and pathways in nerve regeneration

Proteomics helps identify previously unrecognized proteins and pathways in nerve regeneration

Using proteomics techniques to study injured optic nerves, researchers at Boston Children's Hospital have identified previously unrecognized proteins and pathways involved in nerve regeneration. Adding back one of these proteins--the oncogene c-myc--they achieved unprecedented optic nerve regeneration in mice when combined with two other known strategies. [More]
Findings provide glimmer of hope for treating diffuse intrinsic pontine gliomas

Findings provide glimmer of hope for treating diffuse intrinsic pontine gliomas

Using brain tumor samples collected from children in the United States and Europe, an international team of scientists found that the drug panobinostat and similar gene regulating drugs may be effective at treating diffuse intrinsic pontine gliomas (DIPG), an aggressive and lethal form of pediatric cancer. [More]
Scientists report that enzyme that alters testosterone to estrogen has big impact in healthy, injured brain

Scientists report that enzyme that alters testosterone to estrogen has big impact in healthy, injured brain

An enzyme that converts testosterone to estrogen appears to have significant impact in a healthy and injured brain, scientists report. [More]
DelMar to present new data on development of VAL-083 at 2015 ASCO Annual Meeting

DelMar to present new data on development of VAL-083 at 2015 ASCO Annual Meeting

DelMar Pharmaceuticals, Inc., today announced that it will be presenting new data related to the development of lead product candidate VAL-083 (dianhydrogalactitol) at the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting, being held May 29-June 2, 2015, in Chicago, Illinois. [More]
ITIM-containing receptor crucial for development of acute myeloid leukemia

ITIM-containing receptor crucial for development of acute myeloid leukemia

UT Southwestern Medical Center scientists have discovered that a certain class of receptors that inhibit immune response are crucial for the development of acute myeloid leukemia (AML), the most common acute leukemia affecting adults. [More]
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