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The nervous system is an organ system containing a network of specialized cells called neurons that coordinate the actions of an animal and transmit signals between different parts of its body. In most animals the nervous system consists of two parts, central and peripheral. The central nervous system contains the brain and spinal cord.
Study evaluates co-occurrence of cancers in patients with central nervous system disorders

Study evaluates co-occurrence of cancers in patients with central nervous system disorders

The study evaluated the co-occurrence of cancers in patients with central nervous system disorders, including Alzheimer's disease, amyotrophic lateral sclerosis, autism spectrum disorders, Down's syndrome, Huntington's disease, multiple sclerosis, Parkinson's disease and schizophrenia. [More]
miRNA expression and inhibition: an interview with Maja Petkovic, AMSBIO

miRNA expression and inhibition: an interview with Maja Petkovic, AMSBIO

RNA interference is a process in which RNA molecules inhibit gene expression. This gene silencing process is controlled by RNA-induced silencing complex or RISC and is initiated by small duplex RNA molecules or miRNA that is present inside cell plasma. [More]
Impax resubmits NDA for RYTARY providing updated safety and stability information

Impax resubmits NDA for RYTARY providing updated safety and stability information

Impax Pharmaceuticals, a division of Impax Laboratories, Inc. (NASDAQ: IPXL), announced today the resubmission of Impax's New Drug Application (NDA) for RYTARY (IPX066) to the U.S. Food and Drug Administration (FDA). [More]

ICB International develops tracer for imaging alpha-synuclein in Parkinson's disease

On March 4, 2014, ICB International, Inc., ("ICBI"), announced the development of a tracer for imaging alpha-synuclein (a-Syn) in Parkinson's-like mice at the Keystone Symposium for Parkinson disease (PD) in Keystone,Colorado. [More]
Acupuncture protects brain neurons against injury in rats following heroin relapse

Acupuncture protects brain neurons against injury in rats following heroin relapse

Heroin abuse can damage many brain areas, including the pedunculopontine tegmental nucleus of the midbrain, the ventral tegmental area, and nucleus accumbens. Persistent use of heroin induced irreversible damage to the nervous system. [More]

Ironwood and Forest commence new DTC patient awareness campaign for LINZESS

awareness campaign for LINZESS, a once-daily treatment for adults with irritable bowel syndrome with constipation or chronic idiopathic constipation. [More]
Older people with memory and thinking problems may have lower risk of dying from cancer

Older people with memory and thinking problems may have lower risk of dying from cancer

Older people who are starting to have memory and thinking problems, but do not yet have dementia may have a lower risk of dying from cancer than people who have no memory and thinking problems, according to a study published in the April 9, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Forest Laboratories, Almirall receive feedback from FDA regarding fixed dose combination of aclidinium/formoterol

Forest Laboratories, Almirall receive feedback from FDA regarding fixed dose combination of aclidinium/formoterol

Forest Laboratories, Inc. and Almirall, S.A. today announced that they have recently received feedback from the U.S. Food and Drug Administration (FDA) regarding the fixed dose combination of aclidinium and formoterol. [More]
White matter linked with cognitive health

White matter linked with cognitive health

A multidisciplinary group of scientists from the Sanders-Brown Center on Aging at the University of Kentucky have identified an interesting connection between the health of the brain tissue that supports cognitive functioning and the presence of dementia in adults with Down syndrome. [More]
NREF president receives Harvey Cushing Medal from AANS

NREF president receives Harvey Cushing Medal from AANS

Each year, the American Association of Neurological Surgeons (AANS) recognizes a neurosurgeon who has made significant contributions to the neurosurgical specialty through leadership, service and dedication. [More]
SLU researcher receives $608,376 grant to design better clinical treatments for multiple sclerosis

SLU researcher receives $608,376 grant to design better clinical treatments for multiple sclerosis

Saint Louis University researcher Daniel Hawiger, M.D., Ph.D., has been awarded $608,376 from the National Multiple Sclerosis Society to gain a better understanding of how the autoimmune process that causes multiple sclerosis (MS) may be stopped or slowed down. [More]
Alkermes announces results from phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia

Alkermes announces results from phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia

Alkermes plc today announced positive topline results from a randomized, double-blind, placebo-controlled phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia. Patients treated once monthly with either 441 mg or 882 mg of aripiprazole lauroxil demonstrated statistically significant reductions from baseline in Positive and Negative Syndrome Scale (PANSS) total scores at week 12, compared to placebo (p<0.001 aripiprazole lauroxil 441 mg, p<0.001 aripiprazole lauroxil 882 mg), which was the prespecified primary endpoint in the study. Based on the positive results from this phase 3 study, Alkermes plans to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) in the third quarter of 2014. [More]
Novartis Institute researcher receives second annual Andrew Carnegie Prize in Mind and Brain Sciences

Novartis Institute researcher receives second annual Andrew Carnegie Prize in Mind and Brain Sciences

Carnegie Mellon University will award the second annual Andrew Carnegie Prize in Mind and Brain Sciences to Ricardo Dolmetsch, global head of neuroscience at the Novartis Institute for Biomedical Research. [More]

Researchers identify potential treatment targets for incurable form of pediatric brain cancer

Researchers from the University of Toronto's Department of Laboratory Medicine and Pathobiology (LMP) have defined potential treatment targets for a previously incurable form of pediatric brain cancer called Diffuse Intrinsic Pontine Glioma (DIPG). [More]
Helium ion radiotherapy provides hope for improved, accurate radiation treatment for young cancer patients

Helium ion radiotherapy provides hope for improved, accurate radiation treatment for young cancer patients

For the first time, researchers have been able to demonstrate that the use of helium ions in radiation therapy could provide accurate treatment to tumours while helping to spare healthy organs. [More]
Neuroinflammation levels higher in patients with chronic fatigue syndrome

Neuroinflammation levels higher in patients with chronic fatigue syndrome

Researchers at the RIKEN Center for Life Science Technologies, in collaboration with Osaka City University and Kansai University of Welfare Sciences, have used functional PET imaging to show that levels of neuroinflammation, or inflammation of the nervous system, are higher in patients with chronic fatigue syndrome than in healthy people. [More]
Harvard stem cell scientists discover potential treatment for amyotrophic lateral sclerosis

Harvard stem cell scientists discover potential treatment for amyotrophic lateral sclerosis

Harvard stem cell scientists have discovered that a recently approved medication for epilepsy may possibly be a meaningful treatment for amyotrophic lateral sclerosis (ALS)-Lou Gehrig's disease, a uniformly fatal neurodegenerative disorder. The researchers are now collaborating with Massachusetts General Hospital to design an initial clinical trial testing the safety of the treatment in ALS patients. [More]
FDA clears Omeros' OMS721 IND for inhibition of complement‑mediated TMAs

FDA clears Omeros' OMS721 IND for inhibition of complement‑mediated TMAs

Omeros Corporation today announced that its Investigational New Drug Application (IND) to evaluate OMS721 for the inhibition of complement‑mediated thrombotic microangiopathies (TMAs) has been cleared by the U.S. Food and Drug Administration. [More]

Study sheds light on brain mechanisms that make schizophrenia patients misinterpret what they see

People with schizophrenia often misinterpret what they see and experience in the world. New research provides insight into the brain mechanisms that might be responsible for this misinterpretation. [More]
Young adults participated in cardio fitness activities may preserve memory, thinking skills in middle age

Young adults participated in cardio fitness activities may preserve memory, thinking skills in middle age

Young adults who run or participate in other cardio fitness activities may preserve their memory and thinking skills in middle age, according to a new study published in the April 2, 2014, online issue of Neurology®, the medical journal of the American Academy of Neurology. Middle age was defined as ages 43 to 55. [More]