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The nervous system is an organ system containing a network of specialized cells called neurons that coordinate the actions of an animal and transmit signals between different parts of its body. In most animals the nervous system consists of two parts, central and peripheral. The central nervous system contains the brain and spinal cord.
U-M researchers identify how amlexanox drug improves metabolism of sugar

U-M researchers identify how amlexanox drug improves metabolism of sugar

Researchers at the University of Michigan have identified how a promising drug in clinical trials for the treatment of obesity and related metabolic disorders improves the metabolism of sugar by generating a new signal between fat cells and the liver. [More]
Altos Therapeutics announces issuance of Mexican patent covering dopamine D2/D3 drug candidates

Altos Therapeutics announces issuance of Mexican patent covering dopamine D2/D3 drug candidates

Altos Therapeutics, LLC announced today that the Mexican Institute of Industrial Property has issued Patent Number 323020 titled, "D2 Antagonists, Methods of Synthesis and Methods of Use". The patent broadly and specifically covers the company's dopamine D2/D3 drug candidates, their pharmaceutical compositions, and their use to treat a number of important gastrointestinal conditions in humans, such as gastroparesis. [More]
Personal gender identity of every human being is reflected in the structure of brain networks

Personal gender identity of every human being is reflected in the structure of brain networks

Our sense of belonging to the male or female gender is an inherent component of the human identity perception. As a general rule, gender identity and physical sex coincide. If this is not the case, one refers to trans-identity or transsexuality. In a current study, brain researcher Georg S. Kanz of the University Clinic for Psychiatry and Psychotherapy of the MedUni Vienna was able to demonstrate that the very personal gender identity of every human being is reflected and verifiable in the cross-links between brain regions. [More]
FDA approves RYTARY for Parkinson's disease treatment

FDA approves RYTARY for Parkinson's disease treatment

Impax Pharmaceuticals, a division of Impax Laboratories, Inc., today announced that the U.S. Food and Drug Administration approved RYTARY, an extended-release oral capsule formulation of carbidopa-levodopa, for the treatment of Parkinson's disease, post-encephalitic parkinsonism, and parkinsonism that may follow carbon monoxide intoxication and / or manganese intoxication. [More]
Study: Synthetic triglyceride oil may provide hope for people with Huntington's disease

Study: Synthetic triglyceride oil may provide hope for people with Huntington's disease

An early study suggests that a synthetic triglyceride oil called triheptanoin may provide hope for people with Huntington's disease. The study is published in the January 7, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
FDA receives Actavis' NDA resubmission for cariprazine

FDA receives Actavis' NDA resubmission for cariprazine

Actavis plc (NYSE: ACT) and Gedeon Richter Plc. today announced that the U.S. Food and Drug Administration (FDA) has acknowledged receipt of Actavis' New Drug Application (NDA) resubmission for its atypical antipsychotic cariprazine, a potent dopamine D3/D2 receptor partial agonist with preferential binding to D3 receptors. [More]
Study: Placental cells may possibly treat damaged nerves

Study: Placental cells may possibly treat damaged nerves

New findings suggest that placental cells may potentially treat damaged nerves possibly leading the way to new treatment for stroke patients. [More]
New study finds that exercise may improve lives of Parkinson's disease patients

New study finds that exercise may improve lives of Parkinson's disease patients

Exercise may help people with Parkinson's disease improve their balance, ability to move around and quality of life, even if it does not reduce their risk of falling, according to a new study published in the December 31, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Palatin begins bremelanotide phase 3 study for treatment of female sexual dysfunction

Palatin begins bremelanotide phase 3 study for treatment of female sexual dysfunction

Palatin Technologies, Inc., a biopharmaceutical company developing targeted, receptor-specific peptide therapeutics for the treatment of diseases with significant unmet medical needs and commercial potential, today announced that it has started its bremelanotide pivotal registration program. [More]
Newron, Zambon announce re-submission of safinamide NDA to FDA

Newron, Zambon announce re-submission of safinamide NDA to FDA

Newron Pharmaceuticals S.p.A., a research and development company focused on novel CNS and pain therapies, and its commercial and development partner Zambon S.p.A., an international pharmaceutical company, announced today that the NDA for safinamide has been re-submitted to the US FDA. [More]
Actavis receives complete response letter for nebivolol/valsartan FDC for treatment of hypertension

Actavis receives complete response letter for nebivolol/valsartan FDC for treatment of hypertension

Actavis plc today confirmed that the Company has received a complete response letter from the U.S. Food and Drug Administration (FDA) for its New Drug Application (NDA) for the fixed-dose combination (FDC) of nebivolol and valsartan for the treatment of hypertension. [More]
FDA approves Namzaric drug for treatment of moderate to severe Alzheimer's disease

FDA approves Namzaric drug for treatment of moderate to severe Alzheimer's disease

Actavis plc and Adamas Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved the New Drug Application (NDA) for Namzaric, a fixed-dose combination (FDC) of memantine hydrochloride extended-release, a NMDA receptor antagonist, and donepezil hydrochloride, an acetylcholinesterase inhibitor. [More]
Deeper cooling does not reduce NICU death among newborns with hypoxic ischemic encephalopathy

Deeper cooling does not reduce NICU death among newborns with hypoxic ischemic encephalopathy

Among full-term newborns with moderate or severe hypoxic ischemic encephalopathy (damage to cells in the central nervous system from inadequate oxygen), receiving deeper or longer duration cooling did not reduce risk of neonatal intensive care unit death, compared to usual care, according to a study in the December 24/31 issue of JAMA. [More]
Researchers describe key group of small DNA fragments in neurone regulation and maturity

Researchers describe key group of small DNA fragments in neurone regulation and maturity

A study led by researchers from the University of Toronto and involving the Centre for Genomic Regulation in Barcelona has described a group of small DNA fragments that are key in neurone regulation and maturity. [More]

Muscle spindle sensory feedback promotes functional recovery after spinal cord injury

After an incomplete spinal cord injury, the body can partially recover basic motor function. So-called muscle spindles and associated sensory circuits back to the spinal cord promote the establishment of novel neuronal connections after injury. [More]
UCLA researchers uncover potential to restore lost memories in patients with early Alzheimer's

UCLA researchers uncover potential to restore lost memories in patients with early Alzheimer's

New UCLA research indicates that lost memories can be restored. The findings offer some hope for patients in the early stages of Alzheimer's disease. [More]
Scientists discover genetic pathway responsible for brain development

Scientists discover genetic pathway responsible for brain development

Scientists at A*STAR's Institute of Medical Biology and Institute of Molecular and Cellular Biology have identified a genetic pathway that accounts for the extraordinary size of the human brain. [More]
New nationwide effort seeks to find novel approaches to treat ASD, intellectual disability

New nationwide effort seeks to find novel approaches to treat ASD, intellectual disability

Some of the genetic diseases that can cause autism spectrum disorder (ASD) and intellectual disability (ID) are so rare that even physicians who specialize in treating them can't be certain they have seen every possible symptom. [More]
UT Southwestern researchers find new potential target for halting tumor growth

UT Southwestern researchers find new potential target for halting tumor growth

UT Southwestern Medical Center researchers have discovered that brain tumors are capable of burning acetate for fuel, providing a new potential target for halting tumor growth. [More]
Secrets of success for pioneering research revealed

Secrets of success for pioneering research revealed

The British Pharmacological Society has announced the secrets of success for pioneering research along with the outcome of its annual 'Putting UK Pharmacology on the Map' vote. The vote selects sites of special scientific interest linked to achievements in pharmacology based on a ballot of MPs, peers and senior members of the scientific community. [More]