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Nearly 179 million cases of acute diarrhea occur each year in the U.S.

Nearly 179 million cases of acute diarrhea occur each year in the U.S.

In the United States, approximately 179 million cases of acute diarrhea occur each year, and most of those cases are entirely preventable, a researcher from The University of Texas Health Science Center at Houston concluded in a New England Journal of Medicine review article. [More]
Nuvo Research collaborates with Ferndale to develop 2 topical dermatology products

Nuvo Research collaborates with Ferndale to develop 2 topical dermatology products

Nuvo Research Inc., a specialty pharmaceutical company with a diverse portfolio of topical and immunology products, today announced a collaboration involving Ferndale Laboratories, Inc. and a leading Contract Research Organization with significant dermatology experience to develop two topical dermatology products based on Nuvo's patented Multiplexed Molecular Penetration Enhancer technology. [More]
Alexion Pharmaceuticals obtains orphan drug designation from EC for Soliris

Alexion Pharmaceuticals obtains orphan drug designation from EC for Soliris

Alexion Pharmaceuticals, Inc. today announced that the European Commission has granted an orphan drug designation (ODD) to Soliris (eculizumab), a first-in-class terminal complement inhibitor, for the prevention of graft rejection following solid organ transplantation. Graft rejection can cause severe injury to the transplanted organ and is a significant barrier to successful transplantation. [More]
Kala Pharmaceuticals completes $22.5 million Series B financing

Kala Pharmaceuticals completes $22.5 million Series B financing

Kala Pharmaceuticals, Inc., a leading developer of innovative ophthalmic products based on the company's proprietary Mucus Penetrating Particle (MPP) platform technology, today announced it has completed a $22.5 million Series B financing. [More]

TWi and Endo Pharmaceuticals settle patent litigation over Lidoderm product

TWi Pharmaceuticals, Inc. today announced that it has entered into a settlement agreement with Endo Pharmaceuticals Inc., Teikoku Seiyaku Co., Ltd. and Teikoku Pharma USA, Inc. to settle all outstanding patent litigation related to TWi's lidocaine topical patch 5% product. [More]
State highlights: Tenn. may send addicted moms to jail; Hawaii autism coverage; Florida medical marijuana

State highlights: Tenn. may send addicted moms to jail; Hawaii autism coverage; Florida medical marijuana

Pregnant women addicted to illegal narcotics or prescription pain pills could soon be jailed in Tennessee under a bill awaiting the governor's signature. [More]

The trials and tribulations of the health law's expanded health insurance coverage

News outlets report how, as the overhaul "chips away" at the nation's number of people without insurance, the law's solutions to the problem often come with challenges of their own. [More]
Anxiety experienced with false-positive mammogram does not negatively impact woman's well-being

Anxiety experienced with false-positive mammogram does not negatively impact woman's well-being

Dartmouth researchers have found that the anxiety experienced with a false-positive mammogram is temporary and does not negatively impact a woman's overall well-being. Their findings are reported in "Consequences of False-Positive Screening Mammograms," which was published online in the April 21, 2014 JAMA Internal Medicine. [More]
New studies may offer hope for people with migraine

New studies may offer hope for people with migraine

Two new studies may offer hope for people with migraine. The two studies released today will be presented at the American Academy of Neurology's 66th Annual Meeting in Philadelphia, April 26 to May 3, 2014. [More]

New painkiller, with fewer side-effects, up for FDA approval

The drug, Moxduo, allows patients to take lower doses of other painkillers. Elsewhere, a Food and Drug Administration official talks about another painkiller, Zohydro. [More]
Pfizer reports positive results from two tofacitinib Phase 3 trials for moderate-to-severe plaque psoriasis

Pfizer reports positive results from two tofacitinib Phase 3 trials for moderate-to-severe plaque psoriasis

Pfizer Inc. announced today top-line results from two pivotal Phase 3 trials from the Oral treatment Psoriasis Trials (OPT) Program, OPT Pivotal #1 (A3921078) and OPT Pivotal #2 (A3921079), evaluating the efficacy and safety of tofacitinib, an oral Janus kinase (JAK) inhibitor, the first in a new class of medicines being investigated for the treatment of moderate-to-severe plaque psoriasis. [More]

P4 pain scale found suitable for use in knee osteoarthritis

The P4 pain scale compares favorably with other commonly used measures for patients with severe knee osteoarthritis, a Canadian study has found. [More]

Nocturnal incontinence poses major burden after female bladder reconstruction

Health-related quality of life is lower in women who have undergone radical cystectomy and neobladder reconstruction for bladder cancer than in the general female population, shows research. [More]
FDA announces expanded approval of Arzerra in combination with chlorambucil for CLL treatment

FDA announces expanded approval of Arzerra in combination with chlorambucil for CLL treatment

The US Food and Drug Administration has announced the expanded approval of Arzerra (ofatumumab) in combination with chlorambucil for the first-line treatment of chronic lymphocytic leukemia (CLL). Arzerra was previously approved by the FDA in October 2009 for the treatment of CLL resistant to other forms of chemotherapy. Diplomat has access to dispense Arzerra. [More]

First Edition: April 22, 2014

Today's early morning highlights from the major news organizations, including marketplace news about the Novartis purchase of GlaxoSmithKline's oncology unit for $14.5 billion. [More]

Scientists uncover key mechanism that regulates nerve cell growth in damaged nervous system

New research published today out of the University of Calgary's Hotchkiss Brain Institute uncovers a mechanism to promote growth in damaged nerve cells as a means to restore connections after injury. Dr. Doug Zochodne and his team have discovered a key molecule that directly regulates nerve cell growth in the damaged nervous system. [More]
Penn study clarifies action of potential new class of pain relievers that may benefit and not hurt heart

Penn study clarifies action of potential new class of pain relievers that may benefit and not hurt heart

Nonsteroidal antinflamatory drugs (NSAIDs) that block an enzyme called COX-2 relieve pain and inflammation but can cause heart attacks, stroke, heart failure, and even sudden cardiac death. [More]

Prevalence of celiac disease on the rise among children with irritable bowel syndrome

There appears to be an increased prevalence of celiac disease among children with irritable bowel syndrome (IBS). [More]

California Orthopaedic Medical Clinic offers comprehensive surgical solution for spinal stenosis

Like any back surgery, spinal stenosis treatment can be a significant and emotionally taxing moment in a person's life – which is why it is essential to ensure that it is effective the first time by trusting treatment to experts like Dr. Seyed M. Rezaian. [More]
Doctors still make good money

Doctors still make good money

An annual survey shows that doctors, on average, still make at least three times the annual median household income. Media outlets also describe other trends, including the return of house calls, often as part of hospital palliative care programs, the use of scribes to help with digital records, rushed doctors' visits and a study finding that free drug samples influence doctors' prescribing practices. [More]