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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Administration of selenide protects heart tissue post cardiac arrest, shows study

Damage to heart muscle from insufficient blood supply during cardiac arrest and reperfusion injury after blood flow is restored can be reduced by nearly 90 percent if selenide, a form of the essential nutrient selenium, is administered intravenously in the wake of the attack, according to a new preclinical study by researchers at Fred Hutchinson Cancer Research Center.

10 Apr 2015

Changing the size and number of pores in processed foods can reduce salt intake

Two University of Illinois food scientists have learned that understanding and manipulating porosity during food manufacturing can affect a food's health benefits.

10 Apr 2015

Scientists identify chemical compounds that block cancer-causing oncoprotein

A team of scientists at the University of Kansas has pinpointed six chemical compounds that thwart HuR, an "oncoprotein" that binds to RNA and promotes tumor growth.

10 Apr 2015

Research opens door to potential drug target for deadly Ebola virus

Opening the door to potential treatments for the deadly Ebola virus, scientists have found that a protein made by the virus plays a role similar to that of a coat-check attendant.

9 Apr 2015

Pharmacyclics announces positive results from IMBRUVICA Phase II study in WM patients

Pharmacyclics, Inc. today announced longer-term data from a Phase II investigator-initiated study showing Waldenstrom's macroglobulinemia (WM) patients treated with IMBRUVICA (ibrutinib) experienced sustained disease control with an overall response rate (ORR) of 91% after a median of 19.1 months of treatment and a 2-year overall survival (OS) rate of 95%.

9 Apr 2015

UQDI reveals that Anisina drug can kill melanoma cells

US-Australian drug discovery company, Novogen, today announced that studies conducted at The University of Queensland Diamantina Institute revealed that experimental drug, Anisina, killed melanoma cells irrespective of their mutational status.

9 Apr 2015

UAB scientists create alternative to the use of viruses in gene therapy

A team of scientists from the Institute for Biotechnology and Biomedicine at the UAB has produced an alternative to the use of viruses in gene therapy. The researchers synthesised nanoparticles which act as artificial viruses, capable of surrounding DNA fragments and releasing them as therapeutic agents, with no biological risk, into the interior of the cells.

9 Apr 2015

Vanderbilt researchers join multi-center effort to accelerate development of potential Ebola therapy

Vanderbilt University researchers have joined a multi-center effort led by Pennsylvania-based Inovio Pharmaceuticals Inc. to accelerate development of potential antibody therapies against the often-lethal Ebola virus.

9 Apr 2015

Neuro-oncology researchers identify mechanism responsible for tumor cell invasion in glioblastoma

A neuro-oncology research team at Dartmouth's Norris Cotton Cancer Center, led by the Director Mark A. Israel, MD with first author Gilbert J. Rahme, PhD, recently identified the transcription factor Id4 as a suppressor of tumor cell invasion in glioblastoma.

9 Apr 2015

Clearer understanding of ORC offers new insight into fundamental DNA replication initiation mechanisms

A clearer understanding of the origin recognition complex (ORC) - a protein complex that directs DNA replication - through its crystal structure offers new insight into fundamental mechanisms of DNA replication initiation. This will also provide insight into how ORC may be compromised in a subset of patients with Meier-Gorlin syndrome, a form of dwarfism in humans.

9 Apr 2015

Yale University-led research explores directional cues that influence cancer cells

Scientists are mapping the habits of cancer cells, turn by microscopic turn. Using advanced technology and an approach that merges engineering and medicine, a Yale University-led team has compiled some of the most sophisticated data yet on the elaborate signaling networks directing highly invasive cancer cells. Think of it as a digital field guide for a deadly scourge.

9 Apr 2015

Plymouth researchers receive grant to develop effective therapy for Huntington's disease

Huntington's disease is an hereditary disorder of the nervous system caused by a faulty gene on chromosome four. The faulty gene leads to nerve damage in the area of the brain resulting in gradual physical, mental and emotional changes. Those born to a parent with Huntington's disease have a 50:50 chance of developing it, and there is currently no cure.

9 Apr 2015

New simeprevir clinical data to be presented at EASL's International Liver Congress 2015

Janssen Sciences Ireland UC, one of the Janssen Pharmaceutical Companies of Johnson & Johnson, today announced that clinical data for simeprevir, its NS3/4A protease inhibitor for the treatment of hepatitis C virus (HCV) infection, will be presented at The International Liver Congress 2015 of the European Association for the Study of the Liver taking place in Vienna from April 22-26.

8 Apr 2015

Researchers reveal molecular structure of cytotoxin from Mycoplasma pneumoniae

Researchers from the School of Medicine at The University of Texas Health Science Center at San Antonio today revealed the molecular structure of the cytotoxin from Mycoplasma pneumoniae, a widespread, highly contagious bacterium that infects the lungs.

8 Apr 2015

Researchers explore influence of low-frequency magnetic fields on neurodegenerative disorders

Low-frequency alternating magnetic fields such as those generated by overhead power lines are considered a potential health risk because epidemiological studies indicate that they may aggravate, among other things, neurodegenerative disorders such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS).

8 Apr 2015

New study could point to potential ways to address defects in learning, memory

Just as some people seem built to run marathons and have an easier time going for miles without tiring, others are born with a knack for memorizing things, from times tables to trivia facts. These two skills—running and memorizing—are not so different as it turns out.

8 Apr 2015

Research finding may lead to new potential therapeutic targets for lung cancer

Lung cancer is the second most common type of cancer and the number one cause of cancer-related mortality. It is estimated that more than 158,000 people will die from lung cancer in the United States this year. Many scientists believe that targeting a type of cell called a cancer stem cell may be necessary to completely cure lung cancer.

8 Apr 2015

St. Luke’s Cancer Center offers new Phase II oncolytic viral therapy clinical trial for advanced melanoma

St. Luke’s Cancer Center is a leader in offering clinical trials for patients with melanoma, the most unusual type of skin cancer and also the most deadly. Physicians such as Sanjiv Agarwala, MD, Chief of Medical Oncology and Hematology for St. Luke’s University Health Network and an internationally recognized melanoma specialist, are committed to bringing the most promising studies to the Lehigh Valley.

8 Apr 2015

Researchers examine catheter-related bloodstream infections in patients receiving home parenteral nutrition

Catheter-related bloodstream infection is the most prevalent and severe complication for patients who receive parenteral nutrition therapy at home.

7 Apr 2015

RNA could be a potential target for new anticancer drugs, say UC Berkeley scientists

Most of today's anticancer drugs target the DNA or proteins in tumor cells, but a new discovery by University of California, Berkeley, scientists unveils a whole new set of potential targets: the RNA intermediaries between DNA and proteins.

7 Apr 2015

Protein News and Research

Further Reading

Administration of selenide protects heart tissue post cardiac arrest, shows study

Changing the size and number of pores in processed foods can reduce salt intake

Scientists identify chemical compounds that block cancer-causing oncoprotein

Research opens door to potential drug target for deadly Ebola virus

Pharmacyclics announces positive results from IMBRUVICA Phase II study in WM patients

UQDI reveals that Anisina drug can kill melanoma cells

UAB scientists create alternative to the use of viruses in gene therapy

Vanderbilt researchers join multi-center effort to accelerate development of potential Ebola therapy

Neuro-oncology researchers identify mechanism responsible for tumor cell invasion in glioblastoma

Clearer understanding of ORC offers new insight into fundamental DNA replication initiation mechanisms

Yale University-led research explores directional cues that influence cancer cells

Plymouth researchers receive grant to develop effective therapy for Huntington's disease

New simeprevir clinical data to be presented at EASL's International Liver Congress 2015

Researchers reveal molecular structure of cytotoxin from Mycoplasma pneumoniae

Researchers explore influence of low-frequency magnetic fields on neurodegenerative disorders

New study could point to potential ways to address defects in learning, memory

Research finding may lead to new potential therapeutic targets for lung cancer

St. Luke’s Cancer Center offers new Phase II oncolytic viral therapy clinical trial for advanced melanoma

Researchers examine catheter-related bloodstream infections in patients receiving home parenteral nutrition

RNA could be a potential target for new anticancer drugs, say UC Berkeley scientists

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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