Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Scientists discover hidden mechanism which could explain why some cancer therapies fail trials

Scientists based at the University of Helsinki, Finland, have discovered a 'hidden' mechanism which could explain why some cancer therapies which aim to block tumour blood vessel growth are failing cancer trials.

31 Jan 2015

Altered dopamine signaling may contribute to autism

Newly discovered genetic variations linked to autism spectrum disorder (ASD) disrupt the function of the dopamine transporter, suggesting that altered dopamine signaling contributes to this common developmental condition, according to a Vanderbilt University-led research team.

31 Jan 2015

Inhibition of SIRT1 protein may hold promise for treatment of metastatic Ewing sarcoma

Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), led by Oscar Martínez Tirado participated in an international study which suggests inhibition of Sirtuin1 (SIRT1) protein as a future treatment option for metastatic Ewing sarcoma. The results of the study were published in the journal Cancer Research.

31 Jan 2015

Project Spark to advance neuroprotective drug for schizophrenia-associated cognitive impairment

A public-private consortium led by the biotech Iproteos -based at Parc Científic de Barcelona (PCB)-, and comprised by the biopharmaceutical company Ascil-Biopharma, the Institute for Biomedical Research (IRB Barcelona), the Centre for Genomic Regulation (CRG) and the University of the Basque Country (UPV/EHU) has launched a project to advance the development of a new neuroprotective drug for the treatment of the cognitive impairment associated with schizophrenia and other mental disorders.

31 Jan 2015

Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

The Damon Runyon Cancer Research Foundation, a non-profit organization focused on supporting innovative early career researchers, named 15 new Damon Runyon Fellows at its fall Fellowship Award Committee review. The recipients of this prestigious, four-year award are outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators across the country.

31 Jan 2015

Nanoscale DNA tool to detect molecular behavior

A complex interplay of molecular components governs almost all aspects of biological sciences - healthy organism development, disease progression, and drug efficacy are all dependent on the way life's molecules interact in the body. Understanding these bio-molecular interactions is critical for the discovery of new, more effective therapeutics and diagnostics to treat cancer and other diseases, but currently requires scientists to have access to expensive and elaborate laboratory equipment.

31 Jan 2015

FDA’s approval of ibrutinib to treat Waldenstrom's macroglobulinemia receives praises from LLS

The U.S. Food and Drug Administration approval of ibrutinib (Imbruvica) to treat patients with Waldenstrom's macroglobulinemia(WM) is a significant advance for patients with this rare blood cancer.

31 Jan 2015

Scientists reveal mechanism underlying cellular degeneration of upper motor neurons

For the first time, scientists have revealed a mechanism underlying the cellular degeneration of upper motor neurons, a small group of neurons in the brain recently shown to play a major role in ALS pathology.

31 Jan 2015

TAU researchers identify novel proteins capable of stymieing growth in antibiotic-resistant bacteria

Antibiotic-resistant infections are on the rise, foiling efforts to reduce death rates in developing countries where uncontrolled use of antibiotics and poor sanitation run amok. The epidemic of "superbugs," bacteria resistant to antibiotics, knows no borders -- presenting a clear and present danger around the globe.

31 Jan 2015

Breast and lung cancer patients with low levels of TTP protein have poorer prognosis

Moffitt Cancer Center researchers have found that breast and lung cancer patients who have low levels of a protein called tristetraprolin (TTP) have more aggressive tumors and a poorer prognosis than those with high levels of the protein.

31 Jan 2015

Pancreatic cancer cells know a way to sidestep chemotherapy, reveal Fox Chase researchers

Pancreatic cancer is one of the deadliest forms of the disease. The American Cancer Society's most recent estimates for 2014 show that over 46,000 people will be diagnosed with pancreatic cancer and more than 39,000 will die from it. Now, research led by Timothy J. Yen, PhD, Professor at Fox Chase Cancer Center, reveals that one reason this deadly form of cancer can be so challenging to treat is because its cells have found a way to sidestep chemotherapy.

30 Jan 2015

Scientists identify strong link between beclin 1 gene and triple-negative breast cancer

UT Southwestern Medical Center scientists have identified a strong link between the most aggressive type of breast cancer and a gene that regulates the body's natural cellular recycling process, called autophagy.

30 Jan 2015

Postprandial glucagon linked to glycaemic control in Type 1 diabetes

Research shows that postprandial glucagon levels increase over time in children with newly diagnosed Type 1 diabetes, and are associated with worsening glycaemic control, suggesting an adjunctive treatment approach.

30 Jan 2015

UCSD, UCSF launch new project to map cancer cells

Researchers from the University of California, San Diego School of Medicine and University of California, San Francisco, with support from a diverse team of collaborators, have launched an ambitious new project - dubbed the Cancer Cell Map Initiative or CCMI - to determine how all of the components of a cancer cell interact.

30 Jan 2015

Researchers identify molecular pathways that could lead to new therapeutic targets for cerebral malaria

A drug already approved for treating other diseases may be useful as a treatment for cerebral malaria, according to researchers at Harvard T. H. Chan School of Public Health. They discovered a novel link between food intake during the early stages of infection and the outcome of the disease, identifying two molecular pathways that could serve as new targets for treatment.

30 Jan 2015

Farnesoid-X receptor could play key role in hepatobiliary and gastrointestinal disorders

The farnesoid-X receptor (FXR), also known as the chief regulator of bile acid metabolism, is thought to play a role in some hepatobiliary and gastrointestinal disorders.

30 Jan 2015

Research reveals key protein structure, paves way for better anti-anxiety drugs

When new medicines are invented, the drug may hit the intended target and nullify the symptoms, but nailing a bull's eye - one that produces zero side effects - can be quite elusive.

30 Jan 2015

Immunomic Therapeutics, Astellas Pharma sign license deal to develop LAMP-vax DNA vaccines

Immunomic Therapeutics, Inc. ("Immunomic Therapeutics"), a company developing next-generation vaccines based on the LAMP-vax platform, and Astellas Pharma Inc. ("Astellas") today announced they have entered into an exclusive license agreement for Japan to develop and commercialize JRC2-LAMP-vax, Immunomic Therapeutics' vaccine designed to treat allergies induced by Japanese red cedar pollen.

30 Jan 2015

Support employees in Ontario vote to ratify agreement between OPSEU and Canadian Blood Services

Canadian Blood Services is pleased to announce that support employees in Ontario, represented by the Ontario Public Service Employees Union (OPSEU), have voted to ratify the agreement recently reached between the two parties.

30 Jan 2015

Park Systems announces innovations in bio cell analysis with the launch of Park NX-Bio

Park Systems, a leading manufacturer of atomic force microscopy (AFM) and nanoscale metrology products, proudly introduces Park NX-Bio, a powerful 3-in-1 bio-research tool that uniquely combines scanning ion conductance microscopy (SICM) with AFM and an inverted optical microscope (IOM) on the same platform.

29 Jan 2015

Protein News and Research

Further Reading

Scientists discover hidden mechanism which could explain why some cancer therapies fail trials

Altered dopamine signaling may contribute to autism

Inhibition of SIRT1 protein may hold promise for treatment of metastatic Ewing sarcoma

Project Spark to advance neuroprotective drug for schizophrenia-associated cognitive impairment

Damon Runyon Cancer Research Foundation names 15 new Damon Runyon Fellows

Nanoscale DNA tool to detect molecular behavior

FDA’s approval of ibrutinib to treat Waldenstrom's macroglobulinemia receives praises from LLS

Scientists reveal mechanism underlying cellular degeneration of upper motor neurons

TAU researchers identify novel proteins capable of stymieing growth in antibiotic-resistant bacteria

Breast and lung cancer patients with low levels of TTP protein have poorer prognosis

Pancreatic cancer cells know a way to sidestep chemotherapy, reveal Fox Chase researchers

Scientists identify strong link between beclin 1 gene and triple-negative breast cancer

Postprandial glucagon linked to glycaemic control in Type 1 diabetes

UCSD, UCSF launch new project to map cancer cells

Researchers identify molecular pathways that could lead to new therapeutic targets for cerebral malaria

Farnesoid-X receptor could play key role in hepatobiliary and gastrointestinal disorders

Research reveals key protein structure, paves way for better anti-anxiety drugs

Immunomic Therapeutics, Astellas Pharma sign license deal to develop LAMP-vax DNA vaccines

Support employees in Ontario vote to ratify agreement between OPSEU and Canadian Blood Services

Park Systems announces innovations in bio cell analysis with the launch of Park NX-Bio

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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