Schizophrenia News and Research RSS Feed - Schizophrenia News and Research

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Neurons in the nose could be the key to early diagnosis of schizophrenia, says researcher

A debilitating mental illness, schizophrenia can be difficult to diagnose. Because physiological evidence confirming the disease can only be gathered from the brain during an autopsy, mental health professionals have had to rely on a battery of psychological evaluations to diagnose their patients. [More]

Delayed psychosis treatment harms chance of success

The longer patients with first-episode psychosis go untreated, the less likely they are to achieve remission within a year of starting treatment, report researchers. [More]
BioLineRx starts enrollment in Phase I/II trial of BL-8020 for treatment of HCV

BioLineRx starts enrollment in Phase I/II trial of BL-8020 for treatment of HCV

BioLineRx, a biopharmaceutical development company, announced today enrollment of the first patient in a Phase I/II trial for BL-8020, an orally available, interferon-free treatment for the Hepatitis C virus. [More]
UC San Diego scientists hope to improve genome-wide association studies

UC San Diego scientists hope to improve genome-wide association studies

As scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly threatened by the unthinkable: Too much data to make full sense of. [More]
Testosterone’s role in schizophrenia

Testosterone’s role in schizophrenia

Researchers from Neuroscience Research Australia (NeuRA) have presented new results about the role of testosterone in schizophrenia at the International Congress on Schizophrenia Research being held in Orlando, Florida. [More]
New methods boost researchers' analytical powers by incorporating prior knowledge about SNPs function

New methods boost researchers' analytical powers by incorporating prior knowledge about SNPs function

As scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly threatened by the unthinkable: Too much data to make full sense of. [More]
Antihistamine drugs work by preventing histamine from attaching to H1 receptors

Antihistamine drugs work by preventing histamine from attaching to H1 receptors

Itchy eyes, scratchy throat, running nose--it's allergy season! What triggers these allergic reactions, and how do allergy medications work? [More]

New technologies speed health care delivery, reduce costs, pioneer new therapies

The current special issue of Technology and Innovation - Proceedings of the National Academy of Inventors, devoted to studies on medical technology and health care delivery, focuses on a wide range of topics, from new technologies to reduce the cost of health care to understanding the human microbiome. [More]

Schizophrenia patients misinterpret anger

A study shows that patients with schizophrenia struggle to recognize angry facial expressions, often mistaking them for fear. [More]
Schizophrenia cardiovascular risk under-recognized in primary care

Schizophrenia cardiovascular risk under-recognized in primary care

UK researchers have found that despite being a major contributor to premature deaths among patients with schizophrenia, cardiovascular disease is less likely to be recorded on their primary care records than people without schizophrenia. [More]

Research supports polygenic phenotype in schizophrenia

Cumulative genetic risk for schizophrenia has been linked to impaired prefrontal brain activity, in findings that support an additive genetic risk model for a polygenic phenotype. [More]

Scientists to develop technology for unprecedented new understanding of how the brain works

The newly proposed scientific project to understand the most complicated 3 pounds of material in the world - the human brain - is the topic of an article in the current edition of Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, the world's largest scientific society. [More]
Alkermes reports topline results from phase 2 study of ALKS 5461 drug for major depressive disorder

Alkermes reports topline results from phase 2 study of ALKS 5461 drug for major depressive disorder

Alkermes plc (NASDAQ: ALKS) today announced positive preliminary topline results from a phase 2 study of ALKS 5461, its novel drug compound for major depressive disorder (MDD) in patients who have an inadequate response to standard therapies for clinical depression. [More]

Advanced microscope reveals process where mutations lead to autism and other diseases

Using spinning disk microscopy on barely day-old zebra fish embryos, University of Oregon scientists have gained a new window on how synapse-building components move to worksites in the central nervous system. [More]
Study: Stem cell transplant heals neurological deficits in mice

Study: Stem cell transplant heals neurological deficits in mice

For the first time, human embryonic stem cells have been transformed into nerve cells that helped mice regain the ability to learn and remember. [More]

Targacept moving forward with Phase 2b study of TC-5619 for treatment of schizophrenia

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today announced that it has completed recruitment of patients in the Phase 2b study of TC-5619 as a treatment for negative symptoms and cognitive dysfunction in schizophrenia. [More]
Excess glutamate drives schizophrenia in high-risk individuals

Excess glutamate drives schizophrenia in high-risk individuals

An excess of the brain neurotransmitter glutamate may cause a transition to psychosis in people who are at risk for schizophrenia, reports a study from investigators at Columbia University Medical Center published in the current issue of Neuron. [More]

FDA authorizes SK Biopharmaceuticals' IND application for SKL15508 to treat CIAS

The Korea-based international pharmaceutical company, SK Biopharmaceuticals, announced today the U.S. Food and Drug Administration has authorized the Investigational New Drug application for SKL15508 to treat cognitive impairment associated with schizophrenia. [More]
New research reveals how acute stress primes brain for improved performance

New research reveals how acute stress primes brain for improved performance

Overworked and stressed out? Look on the bright side. Some stress is good for you. "You always think about stress as a really bad thing, but it's not," said Daniela Kaufer, associate professor of integrative biology at the University of California, Berkeley. [More]
Phase IIa study shows safety and efficacy of BL-7040 in treating ulcerative colitis

Phase IIa study shows safety and efficacy of BL-7040 in treating ulcerative colitis

BioLineRx, a biopharmaceutical development company, announced today positive Phase IIa results for BL-7040, an orally available drug for treating inflammatory bowel disease. [More]