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Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands
Study shows effects of intensive weight reduction on normal weight females

Study shows effects of intensive weight reduction on normal weight females

Worries about the potential negative consequences of fat loss regimens for aesthetic purposes in normal weight females have been surfacing in the media. [More]
Study establishes harmonized reference ranges for total testosterone in men

Study establishes harmonized reference ranges for total testosterone in men

A large study of more than 9,000 men has established harmonized reference ranges for total testosterone in men that when applied to assays that have been appropriately calibrated will effectively enable clinicians to make a correct diagnosis of hypogonadism, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
A new strategy to fight prostate cancer

A new strategy to fight prostate cancer

A new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer. [More]
U-M researchers identify gene expression linked to gender differences in autoimmune diseases

U-M researchers identify gene expression linked to gender differences in autoimmune diseases

Women represent nearly 8 out of every 10 people with autoimmune diseases. Although the statistics are well-known, the scientific community is still trying to figure out why women's immune systems are more likely to become overactive and attack their own healthy cells. [More]
Scientists discover new class of host molecules to transport steroids in the body

Scientists discover new class of host molecules to transport steroids in the body

Synthetic hosts are to transport medical substances and hormones into the body and to release them at specific points. [More]
Factors that impact fertility in men

Factors that impact fertility in men

Starting a family can be a stressful process, and there are things that can affect your plans that you may not have considered. According to the Centers for Disease Control and Prevention (CDC), an estimated 18 percent of men who sought help with a fertility specialist were diagnosed with a male-related infertility. [More]
Enzyme that cleaves beta carotene may control testosterone levels

Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found. [More]
Many women dissatisfied with length of time for diagnosis of PCOS, survey finds

Many women dissatisfied with length of time for diagnosis of PCOS, survey finds

A large international survey of women with a common condition called polycystic ovary syndrome (PCOS), which is characterized by reproductive and metabolic problems, found nearly two in three were dissatisfied with the length of time they waited and the number of healthcare professionals they had to see before they received a diagnosis, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
Exposure to licorice compound disrupts steroid sex hormone production in ovary

Exposure to licorice compound disrupts steroid sex hormone production in ovary

A study of mouse reproductive tissues finds that exposure to isoliquiritigenin, a compound found in licorice, disrupts steroid sex hormone production in the ovary, researchers report. [More]
Researchers find timing, duration of androgen exposure can influence genital defects in female mice

Researchers find timing, duration of androgen exposure can influence genital defects in female mice

University of Florida researchers have identified cells targeted by a male hormone and found that an excess of that hormone at a specific time can cause genital defects in female mice. [More]
Vigorous, regular aerobic exercise boosts testosterone levels in overweight and obese men

Vigorous, regular aerobic exercise boosts testosterone levels in overweight and obese men

Twelve weeks of aerobic exercise significantly boosted testosterone levels in overweight and obese men, with the greatest increases seen among vigorous exercisers, according to research presented today at the Integrative Biology of Exercise 7 meeting in Phoenix. [More]
Zika virus infection can break down and damage testes of male mice, new research shows

Zika virus infection can break down and damage testes of male mice, new research shows

New research in male mice has revealed that Zika virus infection can break down and severely damage the animals' testes. [More]
Men can take contraceptives to prevent pregnancy in female partners, study shows

Men can take contraceptives to prevent pregnancy in female partners, study shows

Men can take birth control shots to prevent pregnancy in their female partners, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
Researchers take significant step forward in genetic sex reprogramming research

Researchers take significant step forward in genetic sex reprogramming research

An international team of researchers, led by the University of Granada, has taken a significant step forward on the research on 'genetic sex reprogramming', which is closer now, although it's still an utopia. [More]
New oncogene may contribute to high incidence of prostate cancer among African American men

New oncogene may contribute to high incidence of prostate cancer among African American men

A team of scientists has identified MNX1 as a new oncogene - a gene than can cause cancer - that is more active in African American prostate cancer than in European American prostate cancer. [More]
Natural compound found in red wine can lower testosterone levels in women with PCOS

Natural compound found in red wine can lower testosterone levels in women with PCOS

Resveratrol—a natural compound found in red wine and grapes—can help address a hormone imbalance in women with polycystic ovary syndrome (PCOS), a leading cause of infertility in women, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
Common hormone therapy to treat prostate cancer may increase dementia risk in men

Common hormone therapy to treat prostate cancer may increase dementia risk in men

A common hormone therapy to treat prostate cancer may double a man's risk of dementia, regardless of his age, Penn Medicine researchers reported in a study published online today in JAMA Oncology. [More]
Endocrine Society issues new guidelines on hypopituitarism

Endocrine Society issues new guidelines on hypopituitarism

The Endocrine Society today issued a Clinical Practice Guideline that recommends treating insufficient hormone levels in individuals with hypopituitarism by replacing hormones at levels as close to the body's natural patterns as possible. [More]
Predominance of testosterone in males may explain sex difference in ACL injury rates

Predominance of testosterone in males may explain sex difference in ACL injury rates

In studies on rats, Johns Hopkins Medicine scientists report new evidence that the predominance of the hormone testosterone in males may explain why women are up to 10 times more likely than men to injure the anterior cruciate ligament (ACL) in their knees. [More]
Ethosomes may be effective carrier system for transdermal delivery

Ethosomes may be effective carrier system for transdermal delivery

Ethosomes are ethanolic nanovesicles that possess abundant amount of ethanol in its core which provides fluidity to the lipid bilayers and thus by this effect, improves the delivery of molecules into the deep skin layers. [More]
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