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Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands
New UTMB study finds no association between testosterone therapy and blood clots in veins

New UTMB study finds no association between testosterone therapy and blood clots in veins

A new study from The University of Texas Medical Branch at Galveston of more than 30,000 commercially insured men is the first large comparative analysis to show that there is no link between testosterone therapy and blood clots in veins. The study found that middle-aged and older men who receive testosterone therapy are not at increased risk of this illness. [More]
Testosterone, cortisol hormones may destabilise financial markets by making traders take more risks

Testosterone, cortisol hormones may destabilise financial markets by making traders take more risks

The hormones testosterone and cortisol may destabilise financial markets by making traders take more risks, according to a study. Researchers simulated the trading floor in the lab by having volunteers buy and sell assets among themselves. They measured the volunteers' natural hormone levels in one experiment and artificially raised them in another. [More]
UCSD researchers report that statins make women aggressive, but men calmer

UCSD researchers report that statins make women aggressive, but men calmer

Statins are a hugely popular drug class used to manage blood cholesterol levels and reduce the risk of heart disease. Previous studies had raised questions about adverse behavioral changes with statins, such as irritability or violence, but findings with statins have been inconsistent. In the first randomized trial to look at statin effects on behavior, researchers at the University of California, San Diego School of Medicine report that aggressive behavior typically declined among men placed on statins (compared to placebo), but typically increased among women placed on statins. [More]
Men referred for borderline testosterone levels have much higher rates of depression than general population

Men referred for borderline testosterone levels have much higher rates of depression than general population

Researchers at the George Washington University, led by Michael S. Irwig, M.D., found that men referred for tertiary care for borderline testosterone levels had much higher rates of depression and depressive symptoms than those of the general population. [More]
New species of tRNA-derived small RNAs contribute to cell proliferation in cancer

New species of tRNA-derived small RNAs contribute to cell proliferation in cancer

Since their discovery in the 1950s, transfer RNAs (tRNAs) have been best known for their role in helping the cell make proteins from messenger RNA templates. However, recent studies have led to a previously-unsuspected concept that tRNAs are not always the end product; namely, they further serve as a source of small RNAs. [More]
TSRI scientists devise powerful set of chemical methods to explore protein biology

TSRI scientists devise powerful set of chemical methods to explore protein biology

Scientists at The Scripps Research Institute (TSRI) have devised a powerful set of chemical methods for exploring the biology of proteins. [More]
Men who use finasteride to treat benign prostate enlargement experience worsening ED

Men who use finasteride to treat benign prostate enlargement experience worsening ED

Men with benign prostate enlargement who used finasteride (also known as proscar and propecia) to treat their condition, experienced worsening erectile dysfunction (ED) that did not resolve with continued treatment. In addition, they experienced a reduction in their testosterone levels leading to hypogonadism (little to no production of sex hormones). [More]
Differences in brain expression of RORA protein levels may lead to sex bias in autism

Differences in brain expression of RORA protein levels may lead to sex bias in autism

George Washington University researcher Valerie Hu, Ph.D., has found an important sex-dependent difference in the level of RORA protein in brain tissues of males and females. Specifically, females without autism have a slightly higher level of RORA in the frontal cortex of the brain than males without autism, while the levels of the protein are comparably lower in the brain of both males and females with autism. [More]
ESSA Pharma reports net loss of $5.9 million for second quarter 2015

ESSA Pharma reports net loss of $5.9 million for second quarter 2015

ESSA Pharma Inc. today reported financial results for the second quarter and three and six months ended March 31, 2015. Amounts, unless specified otherwise, are expressed in Canadian dollars and in accordance with International Financial Reporting Standards. [More]
Novel discovery offers new insight into why women more likely than men to develop MS

Novel discovery offers new insight into why women more likely than men to develop MS

An innocent mistake made by a graduate student in a Northwestern Medicine lab (she accidentally used male mice instead of female mice during an experiment) has led scientists to a novel discovery that offers new insight into why women are more likely than men to develop autoimmune diseases such as multiple sclerosis (MS). [More]
GnRH infusion recommended for adolescent hypogonadotropic hypogonadodism

GnRH infusion recommended for adolescent hypogonadotropic hypogonadodism

Pulsatile gonadotropin-releasing hormone may be more effective than human chorionic gonadotropin for the treatment of peripubescent boys with hypogonadotropic hypogonadodism, say Chinese researchers. [More]

Goethe University researchers find endocrine disrupting chemicals in plastic baby teethers

In laboratory tests, two out of ten teethers, plastic toys used to sooth babies' teething ache, release endocrine disrupting chemicals. One product contains parabens, which are normally used as preservatives in cosmetics, while the second contains six so-far unidentified endocrine disruptors. [More]
Prostate cancer patients can experience cognitive impairment following androgen deprivation therapy

Prostate cancer patients can experience cognitive impairment following androgen deprivation therapy

Cognitive impairment can occur in cancer patients who are treated with a variety of therapies, including radiation therapy, hormone therapy, and chemotherapy. [More]
Prostate cancer patients who receive androgen deprivation therapy may experience cognitive problems

Prostate cancer patients who receive androgen deprivation therapy may experience cognitive problems

Cognitive impairment can occur in cancer patients who are treated with a variety of therapies, including radiation therapy, hormone therapy, and chemotherapy. After chemotherapy treatment it is commonly called "chemo brain." Signs of cognitive impairment include forgetfulness, inability to concentrate, problems recalling information, trouble multi-tasking and becoming slower at processing information. [More]
Cholesterol-lowering statin drugs could delay prostate cancer growth in patients receiving ADT

Cholesterol-lowering statin drugs could delay prostate cancer growth in patients receiving ADT

Men who went on cholesterol-lowering statin drugs when they began androgen deprivation therapy for prostate cancer had a longer time in which their disease was under control than did men who didn't take statins, a clinical trial led by Dana-Farber Cancer Institute investigators shows. [More]
Scientists report that enzyme that alters testosterone to estrogen has big impact in healthy, injured brain

Scientists report that enzyme that alters testosterone to estrogen has big impact in healthy, injured brain

An enzyme that converts testosterone to estrogen appears to have significant impact in a healthy and injured brain, scientists report. [More]
Long-term histrelin implant shows promise for central precocious puberty

Long-term histrelin implant shows promise for central precocious puberty

Long-term subcutaneous histrelin implant therapy is a viable option for patients with central precocious puberty who require continuous gonadotropin-releasing hormone analogue therapy, say researchers. [More]
Health food stores promote adult-only dietary supplements to minors

Health food stores promote adult-only dietary supplements to minors

Fifteen year olds are not only able to buy over-the-counter dietary supplements from a sampling of health food stores across the country, the staff at those stores actually went so far as to recommend certain products, despite labels reading "for adult use only." [More]
High status gestures assumed to stimulate psychological, physiological processes

High status gestures assumed to stimulate psychological, physiological processes

Hands pressed to the hips or perhaps leaning back with arms crossed behind the head are typical poses of power. Referred to power poses or high status gestures in technical jargon, they are assumed to stimulate both psychological and physiological processes. [More]
Study suggests link between androgens, atherosclerosis and obesity in females

Study suggests link between androgens, atherosclerosis and obesity in females

While testosterone replacement therapies may be controversial in males, new research in The FASEB Journal may extend this controversy to females too. That's because research involving mice, appearing in the April 2015 issue, suggests that there is an association between low levels of androgens (which includes testosterone), and atherosclerosis and obesity in females. [More]
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