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Testosterone is a steroid hormone from the androgen group. In mammals, testosterone is primarily secreted in the testes of males and the ovaries of females, although small amounts are also secreted by the adrenal glands
Rockefeller University researchers gain new insight into how cholesterol processes in our body

Rockefeller University researchers gain new insight into how cholesterol processes in our body

In spite of its dangerous reputation, cholesterol is in fact an essential component of human cells. Manufactured by the cells themselves, it serves to stiffen the cell's membrane, helping to shape the cell and protect it. By mapping the structure of a key enzyme involved in cholesterol production, Rockefeller University researchers and a colleague in Italy have gained new insight into this complex molecular process. [More]
Hormone loss may cause colon cancer, say Thomas Jefferson University researchers

Hormone loss may cause colon cancer, say Thomas Jefferson University researchers

Some cancers, like breast and prostate cancer, are driven by hormones such as estrogen and testosterone, but to date, there are none that are driven by the lack of a hormone. New evidence suggests that human colon cells may become cancerous when they lose the ability to produce a hormone that helps the cells maintain normal biology. If verified by further studies, it suggests that treating patients at high risk for colon cancer by replacing the hormone guanylin could prevent the development of cancer. [More]
Endo International enters into definitive agreement to acquire Auxilium Pharmaceuticals

Endo International enters into definitive agreement to acquire Auxilium Pharmaceuticals

Endo International plc and Auxilium Pharmaceuticals, Inc. today announced that they have entered into a definitive agreement under which Endo will acquire all of the outstanding shares of common stock of Auxilium for a per share consideration of $33.25 in a cash and stock transaction. [More]
Testosterone therapy raises risk of prostate tumors in rats

Testosterone therapy raises risk of prostate tumors in rats

A researcher who found that testosterone raised the risk of prostate tumors and exacerbated the effects of carcinogenic chemical exposure in rats is urging caution in prescribing testosterone therapy to men who have not been diagnosed with hypogonadism, according to a new study published in the Endocrine Society's journal Endocrinology. [More]
Endocrine Society issues updated Clinical Practice Guideline on androgens in women

Endocrine Society issues updated Clinical Practice Guideline on androgens in women

The Endocrine Society today issued a Clinical Practice Guideline (CPG) advising against the use of testosterone therapy in healthy women. [More]
Phase 3 COU-AA-302 results show ZYTIGA plus prednisone prolongs overall survival in men with chemotherapy-naive mCRPC

Phase 3 COU-AA-302 results show ZYTIGA plus prednisone prolongs overall survival in men with chemotherapy-naive mCRPC

A final analysis of the Phase 3 COU-AA-302 trial presented today at the European Society for Medical Oncology (ESMO) 2014 Congress in Madrid, Spain showed that ZYTIGA® (abiraterone acetate) plus prednisone significantly prolonged overall survival (OS), compared to an active control of placebo plus prednisone, in men with chemotherapy-naive metastatic castration-resistant prostate cancer (mCRPC). [More]
HerKare opens new location in Mansfield, Texas

HerKare opens new location in Mansfield, Texas

HerKare opens a new location today in Mansfield, Texas. This marks HerKare's third center in Dallas-Fort Worth. HerKare recently expanded to Houston area and continues to accelerate their growth plans, making the treatment of hormonal imbalance in women more convenient. [More]
Sex hormone that helps protect females from stroke may also reduce risk of autism, say scientists

Sex hormone that helps protect females from stroke may also reduce risk of autism, say scientists

The same sex hormone that helps protect females from stroke may also reduce their risk of autism, scientists say. [More]
Low free testosterone predicts prostate cancer reclassification

Low free testosterone predicts prostate cancer reclassification

Lower levels of free testosterone predict an increased likelihood of disease reclassification in men with prostate cancer, researchers report. [More]
Endo International introduces topical testosterone gel, FORTESTA Gel

Endo International introduces topical testosterone gel, FORTESTA Gel

Endo International plc announced today that it has introduced the first and only generic 2% topical testosterone gel, an authorized generic of FORTESTA® Gel (testosterone gel) CIII. [More]
Measuring levels of sex hormones in patients' blood may identify risk of sudden cardiac arrest

Measuring levels of sex hormones in patients' blood may identify risk of sudden cardiac arrest

Measuring the levels of sex hormones in patients' blood may identify patients likely to suffer a sudden cardiac arrest, a heart rhythm disorder that is fatal in 95 percent of patients. [More]
Facial masculinity negatively associated with semen quality

Facial masculinity negatively associated with semen quality

Contrary to what one might expect, facial masculinity was negatively associated with semen quality in a recent Journal of Evolutionary Biology study. [More]
Low dose of opioids including methadone effective for treatment of testosterone suppression

Low dose of opioids including methadone effective for treatment of testosterone suppression

Treatment for opioid addiction tampers with the testosterone levels of male but not female opioid users, McMaster University research has shown. [More]
Auxilium Pharmaceuticals' CCH drug effective against cellulite in Phase 2a study

Auxilium Pharmaceuticals' CCH drug effective against cellulite in Phase 2a study

Auxilium Pharmaceuticals, Inc., a specialty biopharmaceutical company, today announced positive results from a randomized, double-blind Phase 2a study of collagenase clostridium histolyticum (or CCH) for the treatment of edematous fibrosclerotic panniculopathy (EFP), commonly known as cellulite. [More]
Decision Resources expands disease-level coverage of Treatment Algorithms Insight Series

Decision Resources expands disease-level coverage of Treatment Algorithms Insight Series

Decision Resources has expanded its disease-level coverage of the Treatment Algorithms Insight Series, which examines U.S. physicians' prescribing behavior, to provide a quantitative analysis of an agent's penetration into each line of therapy. [More]
Study: Effects of testosterone on brain's response to threat cues in healthy men

Study: Effects of testosterone on brain's response to threat cues in healthy men

A new study in Biological Psychiatry reports on a neural circuit for male aggression. Testosterone, a steroid hormone, is well known to contribute to aggressive behavior in males, but the neural circuits through which testosterone exerts these effects have not been clear. [More]
Auxilium Pharmaceuticals' total revenues decrease 17% to $83 million in Q2 2014

Auxilium Pharmaceuticals' total revenues decrease 17% to $83 million in Q2 2014

Auxilium Pharmaceuticals, Inc., a fully integrated specialty biopharmaceutical company, today announced financial results for the second quarter ending June 30, 2014. The Company highlighted important corporate, commercial, regulatory and clinical development updates from the quarter. [More]
Minister Ambrose calls for proposals to tackle prescription drug abuse

Minister Ambrose calls for proposals to tackle prescription drug abuse

The Honourable Rona Ambrose, Minister of Health, today issued a national Call for Proposals to improve the prescribing practices for prescription drugs that have a high risk of abuse or addiction. [More]
Health Canada offers tips on proper use of topical antiseptics to reduce infections

Health Canada offers tips on proper use of topical antiseptics to reduce infections

Health Canada is reminding healthcare professionals, caregivers and consumers of the safe use of topical antiseptics used to clean the skin before an operation (preoperative) or before an injection (preinjection). [More]
Research suggests effective role for natural steroid hormones in treating breast cancer

Research suggests effective role for natural steroid hormones in treating breast cancer

A new study supports a growing body of research suggesting a safe and effective role for natural steroid hormones in treating postmenopausal breast cancer, with fewer detrimental side effects and improved health profile than with standard anti-hormone therapies. [More]