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Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.
CTI Biotechnology implements Xybion's Pristima 7 Preclinical Suite

CTI Biotechnology implements Xybion's Pristima 7 Preclinical Suite

Xybion Corporation, leading provider of preclinical R&D solutions announced today that CTI Biotechnology in Suzhou, China has implemented Xybion's Pristima 7 Preclinical Suite. Pristima® was selected after an exhaustive evaluation of top selling preclinical software systems on the market. [More]
Tiny aquatic flatworms could replace existing animal models used in neurotoxicity tests

Tiny aquatic flatworms could replace existing animal models used in neurotoxicity tests

Laboratories that test chemicals for neurological toxicity could reduce their use of laboratory mice and rats by replacing these animal models with tiny aquatic flatworms known as freshwater planarians. [More]
E2F4 biomarker can help predict prognosis and response to BCG therapy in bladder cancer

E2F4 biomarker can help predict prognosis and response to BCG therapy in bladder cancer

Investigators from Dartmouth's Norris Cotton Cancer Center harnessed genomic data to discover that the previously identified E2F4 signature in breast cancer can be utilized to predict prognosis and response to therapy in bladder cancer. [More]
UB study sheds light on the molecular basis of cocaine addiction

UB study sheds light on the molecular basis of cocaine addiction

Researchers at the University at Buffalo have discovered a previously unknown neural pathway that can regulate changes made in the brain due to cocaine use, providing new insight into the molecular basis of cocaine addiction. [More]
ESCMID introduces two new study groups to create networks for forensic and veterinary microbiology

ESCMID introduces two new study groups to create networks for forensic and veterinary microbiology

The European Society of Clinical Microbiology and Infectious Diseases launched two new study groups; the Forensic and Postmortem Microbiology Study Group and the Veterinary Microbiology Study Group. [More]
Bio-Techne to acquire 100% ownership of Cliniqa

Bio-Techne to acquire 100% ownership of Cliniqa

Bio-Techne Corporation announced today that it has agreed to acquire 100% ownership of Cliniqa Corporation. Cliniqa specializes in the manufacturing and commercialization of quality controls and calibrators as well as bulk reagents used in the clinical diagnostic market. [More]
Novel strategy shows aptamer-based modular delivery of microRNA in endothelial, breast cancer cells

Novel strategy shows aptamer-based modular delivery of microRNA in endothelial, breast cancer cells

Researchers have shown that a novel delivery strategy can efficiently introduce a functional microRNA that has anti-cancer and angiogenic activities into two different types of cells--breast cancer cells to inhibit tumor growth and metastasis, and cells that line blood vessels to protect against atherosclerosis. [More]
Genticel announces positive results of new multivalent HPV therapeutic vaccine based on Vaxiclase platform

Genticel announces positive results of new multivalent HPV therapeutic vaccine based on Vaxiclase platform

Genticel, a French biotechnology company and developer of innovative immunotherapies to prevent cancers caused by the human papillomavirus (HPV), announces today positive preclinical in vivo proof of concept results of GTL002, its multivalent HPV therapeutic vaccine candidate based on the Company’s versatile Vaxiclase platform. [More]

Alere announces cash dividend of $3.00 per share on its Series B Convertible Perpetual Preferred Stock

Alere Inc., a global leader in rapid diagnostics, today has declared a cash dividend of $3.00 per share on its Series B Convertible Perpetual Preferred Stock (NYSE: ALR.PR.B). [More]
Two grants to bolster research on why ovarian cancer is resistant to chemotherapy

Two grants to bolster research on why ovarian cancer is resistant to chemotherapy

Determining which strains of cancer will eventually become resistant to chemotherapy could be key in figuring out more effective and targeted forms of treatment. Finding the genes responsible for chemo-resistance is what Jeremy Chien, Ph.D., member of the Cancer Biology Program at The University of Kansas Cancer Center, is looking to do with an innovative system that draws inspiration from the early days of cancer gene research. [More]
Scientists study active substance against dreaded hospital pathogen Staphylococcus aureus

Scientists study active substance against dreaded hospital pathogen Staphylococcus aureus

In the German Center for Infection Research (DZIF), scientists from the universities of Tübingen, Münster and Munich join forces and prepare together with the company Hyglos clinical studies on an active substance against the dreaded hospital pathogen Staphylococcus aureus: A highly effective protein from bacteria-specific viruses, so-called bacteriophages, shall rapidly kill the bacteria, which frequently occur in the nose. [More]
TxCell to deliver two presentations on Col-Treg and Ovasave at ISCT Annual Meeting

TxCell to deliver two presentations on Col-Treg and Ovasave at ISCT Annual Meeting

TxCell SA, a biotechnology company developing innovative, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that Dr. Arnaud Foussat, VP Research and New Products, TxCell, will deliver two presentations at the 21st Annual Meeting of the International Society of Cellular Therapy, May 27-30, 2015, in Las Vegas, Nevada, US. [More]
Practical guidance to ensure safe use of flavourings in e-cigarettes

Practical guidance to ensure safe use of flavourings in e-cigarettes

The first practical guide to ensure the safe use of flavourings in e-cigarettes has been published. E-cigarettes and other vaping products contain a nicotine-based liquid that is vapourised and inhaled. There is no combustion so the user inhales vapour, not smoke. This means that e-cigarettes deliver nicotine without smoke toxicants. However, some in the public health community still have expressed concerns over the potential health impacts of flavourings used in e-cigarettes. [More]
UB researchers identify mechanisms behind some autistic behaviors, suggest potential targets

UB researchers identify mechanisms behind some autistic behaviors, suggest potential targets

Scientists at the University at Buffalo have identified the mechanisms behind a genetic mutation that produces certain autistic behaviors in mice, as well as therapeutic strategies to restore normal behaviors. [More]
UH pharmacy students receive awards for excellence in clinical skills, disease management

UH pharmacy students receive awards for excellence in clinical skills, disease management

University of Houston pharmacy students wrapped up the spring semester with awards for excellence in professional service, clinical skills and disease management, earning kudos at the state level from the Texas Society of Health-System Pharmacists. [More]
Goethe University researchers find endocrine disrupting chemicals in plastic baby teethers

Goethe University researchers find endocrine disrupting chemicals in plastic baby teethers

In laboratory tests, two out of ten teethers, plastic toys used to sooth babies' teething ache, release endocrine disrupting chemicals. One product contains parabens, which are normally used as preservatives in cosmetics, while the second contains six so-far unidentified endocrine disruptors. [More]
Experimental gene therapy holds promise against metastatic prostate cancer

Experimental gene therapy holds promise against metastatic prostate cancer

Even with the best available treatments, the median survival of patients with metastatic, hormone-refractory prostate cancer is only two to three years. Driven by the need for more effective therapies for these patients, researchers at VCU Massey Cancer Center and the VCU Institute of Molecular Medicine have developed a unique approach that uses microscopic gas bubbles to deliver directly to the cancer a viral gene therapy in combination with an experimental drug that targets a specific gene driving the cancer's growth. [More]
Scientists identify gene that causes hereditary hypertension and brachydactyly type E

Scientists identify gene that causes hereditary hypertension and brachydactyly type E

Individuals with this altered gene have hereditary hypertension (high blood pressure) and at the same time a skeletal malformation called brachydactyly type E, which is characterized by unusually short fingers and toes. The effect on blood pressure is so serious that -- if left untreated -- it most often leads to death before age fifty. [More]
Study findings challenge current thinking on BPA toxicology

Study findings challenge current thinking on BPA toxicology

Johns Hopkins Bloomberg School of Public Health researchers say that while a large majority of newborns are exposed in their earliest days to bisphenol A (BPA), a much-studied chemical used in plastics and in food and soda can linings, they can chemically alter and rid their bodies of it. [More]
Researchers describe natural mechanism that helps repair lesions in teeth

Researchers describe natural mechanism that helps repair lesions in teeth

Researchers at Inserm and Paris Descartes University have just taken an important step in research on stem cells and dental repair. They have managed to isolate dental stem cell lines and to describe the natural mechanism by which they repair lesions in the teeth. This fundamental discovery will make it possible to initiate unprecedented therapeutic strategies to mobilise the resident dental stem cells and magnify their natural capacity for repair. [More]
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