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Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.
Study findings challenge current thinking on BPA toxicology

Study findings challenge current thinking on BPA toxicology

Johns Hopkins Bloomberg School of Public Health researchers say that while a large majority of newborns are exposed in their earliest days to bisphenol A (BPA), a much-studied chemical used in plastics and in food and soda can linings, they can chemically alter and rid their bodies of it. [More]
Researchers describe natural mechanism that helps repair lesions in teeth

Researchers describe natural mechanism that helps repair lesions in teeth

Researchers at Inserm and Paris Descartes University have just taken an important step in research on stem cells and dental repair. They have managed to isolate dental stem cell lines and to describe the natural mechanism by which they repair lesions in the teeth. This fundamental discovery will make it possible to initiate unprecedented therapeutic strategies to mobilise the resident dental stem cells and magnify their natural capacity for repair. [More]
Scientists report novel approach to reverse Parkinson's-like symptoms in rats

Scientists report novel approach to reverse Parkinson's-like symptoms in rats

As baby boomers age, the number of people diagnosed with Parkinson's disease is expected to increase. Patients who develop this disease usually start experiencing symptoms around age 60 or older. Currently, there's no cure, but scientists are reporting a novel approach that reversed Parkinson's-like symptoms in rats. [More]
Female liver cells become more susceptible to adverse effects of drugs, study finds

Female liver cells become more susceptible to adverse effects of drugs, study finds

Female liver cells, and in particular those in menopaused women, are more susceptible to adverse effects of drugs than their male counterparts, according to new research carried out by the JRC. It is well known that women are more vulnerable when it comes to drug-induced liver effects, but it's the first time it has been shown that there are differences at cellular level. [More]

BioReliance inks non-exclusive license agreement with QTS for proprietary B-CLEAR technology

BioReliance, Sigma-Aldrich Corporation's biologics and early-development services business under SAFC Commercial, is pleased to announce a non-exclusive license agreement with Qualyst Transporter Solutions for its proprietary B-CLEAR technology. [More]
MSU researchers receive $7 million NIH grant to study link between belly fat and high blood pressure

MSU researchers receive $7 million NIH grant to study link between belly fat and high blood pressure

Michigan State University researchers, who were the first to suggest that high blood pressure could be caused by belly fat hormones "talking" with blood vessels in the abdomen, have received a nearly $7 million National Institutes of Health grant to further their work. [More]
Research findings could bolster efforts to develop next gen of anti-viral treatments

Research findings could bolster efforts to develop next gen of anti-viral treatments

A newly developed spectroscopy method is helping to clarify the poorly understood molecular process by which an anti-HIV drug induces lethal mutations in the virus's genetic material. [More]
Study: BPA exposure during pregnancy affects fertility, reproductive function

Study: BPA exposure during pregnancy affects fertility, reproductive function

When scientists exposed pregnant mice to levels of bisphenol A equivalent to those considered safe in humans, three generations of female mouse offspring experienced significant reproductive problems, including declines in fertility, sexual maturity and pregnancy success, the scientists report in the journal Toxicology and Applied Pharmacology. [More]
Oxycodone-related deaths drop 25% after implementation of Prescription Drug Monitoring Program

Oxycodone-related deaths drop 25% after implementation of Prescription Drug Monitoring Program

Oxycodone-related deaths dropped 25 percent after Florida implemented its Prescription Drug Monitoring Program in late 2011 as part of its response to the state's prescription drug abuse epidemic, according to a team of UF Health researchers. The drop in fatalities could stem from the number of health care providers who used the program's database to monitor controlled substance prescriptions. [More]
Clyde Biosciences, a leading drug toxicity testing company, closes Series A investment

Clyde Biosciences, a leading drug toxicity testing company, closes Series A investment

Clyde Biosciences Ltd. (Clyde Biosciences) has announced a £2 million ‘Series A’ investment led by Epidarex Capital, a leading international early-stage life science venture capital fund. Scottish Enterprise’s investment arm, the Scottish Investment Bank, also participated in the round along with Glasgow University Holdings, Ltd. [More]
Experimental oligonucleotide-based drug stimulates human immune system to fight infections

Experimental oligonucleotide-based drug stimulates human immune system to fight infections

An experimental single-stranded oligonucleotide-based drug, MGN1703, comprised only of natural DNA components, stimulates the human immune system to fight infections and attack cancer cells without causing the harmful side effects associated with similar compounds that also contain non-natural DNA components. [More]
Alere i Strep A test receives marketing clearance from FDA

Alere i Strep A test receives marketing clearance from FDA

Alere Inc., a global leader in rapid diagnostic tests, today announced that its Alere i Strep A test has received marketing clearance from the U.S. Food and Drug Administration. Alere i Strep A is the first molecular test that detects Group A Streptococcus (GAS) bacteria in throat swab specimens in 8 minutes or less. [More]
Selvita commences IND-enabling studies for its first oncology drug candidate

Selvita commences IND-enabling studies for its first oncology drug candidate

Selvita, the largest drug discovery company in Central and Eastern Europe, announced today that it is commencing IND-enabling studies for SEL24 project, the company’s first oncology drug candidate. [More]
Ultrafine particle exposure may affect cardiac function

Ultrafine particle exposure may affect cardiac function

The adverse health effects caused by fine particles have been known for some time. In addition, ultrafine particles appear to play a significant role in cardiac function - even if an individual is exposed to these for only a few minutes, as scientists of Helmholtz Zentrum München have now been able to show. [More]

Thermo Fisher Scientific to resell Prosolia’s PaperSpray® technology as factory option to its mass spectrometers

Labs performing clinical research and forensic toxicology of dried sample spots can now purchase Thermo Scientific mass spectrometry (MS) systems equipped from the factory with PaperSpray technology, designed to virtually eliminate sample preparation for screening and quantitation of drugs in biological fluid samples. [More]
Iron oxide nanoparticles selectively target cell surface markers in tumor microenvironments

Iron oxide nanoparticles selectively target cell surface markers in tumor microenvironments

Nanoparticles hold great promise for cancer diagnostics and therapies, but only to the extent that they can be selectively guided to tumors and cancer cells. [More]
3D respiratory tissue model shown to be effective for measuring impact of chemicals

3D respiratory tissue model shown to be effective for measuring impact of chemicals

A 3-dimensional model of human respiratory tissue has been shown to be an effective platform for measuring the impact of chemicals, like those found in cigarette smoke, or other aerosols on the lung. [More]
Scientists establish scientific basis for scalp cooling that can ensure hair retention after cancer treatment

Scientists establish scientific basis for scalp cooling that can ensure hair retention after cancer treatment

HAIR loss is one of the most distressing side-effects of cancer treatment and can even deter some patients from undergoing life-saving chemotherapy. But researchers at the University of Huddersfield are establishing the scientific basis for a rapidly-advancing scalp cooling technology that can ensure hair retention in a vast number of cases. [More]
Biological clue could help explain why some drinkers can't resist alcohol

Biological clue could help explain why some drinkers can't resist alcohol

Virginia Commonwealth University School of Medicine researchers have discovered a biological clue that could help explain why some drinkers develop a dependence on alcohol and others do not. [More]
Experimental drug that attacks brain tumor cells passes early tests

Experimental drug that attacks brain tumor cells passes early tests

An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has passed early tests in animal models and human tissue cultures, say Houston Methodist scientists. [More]
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