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Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.
Nicotine, cotinine can potentially inhibit DNA damage caused by NNK in tobacco smoke

Nicotine, cotinine can potentially inhibit DNA damage caused by NNK in tobacco smoke

A new in vitro study has revealed that nicotine and cotinine, a metabolite of nicotine, can potentially inhibit DNA damage caused by a certain carcinogen in smoke. [More]
Randox expands major supplier agreement with Novation

Randox expands major supplier agreement with Novation

Randox Laboratories has further expanded its market presence in the United States, having been awarded a major supplier agreement with Novation, the leading health care supply chain expertise, analytics and contracting company. [More]
RX daytona+ provides high quality testing on compact easy to use platform

RX daytona+ provides high quality testing on compact easy to use platform

Randox has developed a versatile range of clinical chemistry analyzers with real cost saving in mind. The RX series of clinical chemistry analyzers provides performance like no other. [More]
Randox's Acusera Immunoassay Speciality 1 quality control receives FDA clearance

Randox's Acusera Immunoassay Speciality 1 quality control receives FDA clearance

In Q3 of 2013, Randox announced that the Food and Drug Administration has approved the company's Acusera Immunoassay Speciality 1 quality control for use in US laboratories. [More]
Research highlights potential cancer risk in non-smokers

Research highlights potential cancer risk in non-smokers

Research led by the University of York has highlighted the potential cancer risk in non-smokers - particularly young children - of tobacco smoke gases and particles deposited to surfaces and dust in the home. [More]
Baxter International acquires drug candidate developed to treat sickle cell disease

Baxter International acquires drug candidate developed to treat sickle cell disease

A drug candidate developed by researchers at the NIH's National Center for Advancing Translational Sciences and its collaborators to treat sickle cell disease has been acquired by Baxter International's BioScience business. [More]
Mice exposed to low doses of arsenic in drinking water develop lung cancer

Mice exposed to low doses of arsenic in drinking water develop lung cancer

Mice exposed to low doses of arsenic in drinking water, similar to what some people might consume, developed lung cancer, researchers at the National Institutes of Health have found. [More]
Genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma

Genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma

Two genetic mutations in liver cells may drive tumor formation in intrahepatic cholangiocarcinoma (iCCA), the second most common form of liver cancer, according to a research published in the July issue of the journal Nature. [More]
A*STAR scientists pioneered a molecular connection between obesity and diabetes

A*STAR scientists pioneered a molecular connection between obesity and diabetes

Scientists from the Institute of Molecular and Cell Biology, a research institute under the Agency for Science, Technology and Research, have discovered that obese individuals lack a protein that is essential for regulating blood glucose levels, causing them to face higher risks of developing diabetes. [More]
INTEGRA introduces Row Dilution Plate Holder accessory for VIAFLO 96 and 384 handheld benchtop pipettes

INTEGRA introduces Row Dilution Plate Holder accessory for VIAFLO 96 and 384 handheld benchtop pipettes

INTEGRA has introduced a Row Dilution Plate Holder accessory for its VIAFLO 96 and 384 handheld benchtop pipettes. [More]
Study measures hazardous concentrations of carbon monoxide on houseboats

Study measures hazardous concentrations of carbon monoxide on houseboats

Boaters and marina workers should exercise caution this summer before taking to the seas. A study published online in the Journal of Occupational and Environmental Hygiene (JOEH) outlines hazards posed by carbon monoxide levels on houseboats that use gasoline-powered generators without emission controls, along with controls that are available to reduce exposure to carbon monoxide from the generators. [More]
EnGeneIC plans for Phase 2a trial of EGFR-targeted doxorubicin-packaged EDV nanocells for GBM

EnGeneIC plans for Phase 2a trial of EGFR-targeted doxorubicin-packaged EDV nanocells for GBM

EnGeneIC, Ltd., an emerging biopharmaceutical company focused on revolutionizing the treatment of cancer through the targeted delivery of therapeutic agents directly to cancer cells, today announced plans to move forward with a Phase 2a clinical trial in the U.S. using its formulation of EGFR-targeted, EDV nanocells packaged with doxorubicin for the treatment of recurrent glioblastoma (GBM), a common and aggressive type of brain tumor. [More]
Small antioxidant molecules suppress colon cancer associated with colitis

Small antioxidant molecules suppress colon cancer associated with colitis

Researchers from Case Western Reserve and Dartmouth universities have shown that a class of small antioxidant molecules carries enormous promise for supressing colon cancer associated with colitis. [More]
Artificial sweetener have potential to limit impact of therapeutic drugs

Artificial sweetener have potential to limit impact of therapeutic drugs

One of the active ingredients in a popular artificial sweetener could have the potential to limit the impact of therapeutic drugs, reduce the number and balance of beneficial bacteria in the gut and alter hormone secretion, according to an article published in Journal of Toxicology and Environmental Health, Part A: Current Issues. [More]
University of Kentucky receives $12.2 million grant to reduce negative health from hazardous chemicals

University of Kentucky receives $12.2 million grant to reduce negative health from hazardous chemicals

The University of Kentucky has received a $12.2 million grant from the National Institutes of Health to continue its work to better understand and minimize negative health and environmental impacts from hazardous waste sites. [More]
Novel microscopy technology helps detect protein that plays key role in prostate cancer

Novel microscopy technology helps detect protein that plays key role in prostate cancer

Assemblies of proteins, known as protein complexes, have important functions in cells; protein complexes embedded in the cell membrane, for example, are responsible for the exchange with the extracellular environment. [More]
Synthetic, Enterome partner to study effects of beta-lactam antibiotics on gastrointestinal microflora

Synthetic, Enterome partner to study effects of beta-lactam antibiotics on gastrointestinal microflora

Synthetic Biologics, Inc., a developer of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and diseases, and Enterome Bioscience SA, a pioneer in the development of innovative disease management solutions based on a deep understanding of the gut microbiome, today announced that they have entered into an agreement to conduct metagenomic research on the effects of beta-lactam antibiotics on the gastrointestinal microflora (microbiome) of human patients. [More]
Penn researchers awarded $10 million grant to study adverse health effects, remediation of asbestos

Penn researchers awarded $10 million grant to study adverse health effects, remediation of asbestos

Researchers at the Center of Excellence in Environmental Toxicology, Perelman School of Medicine at the University of Pennsylvania, have been awarded a $10 million grant from the National Institute for Environmental Health Sciences over the next four years to study asbestos exposure pathways that lead to mesothelioma, the bioremediation of this hazardous material, and mechanisms that lead to asbestos-related diseases. [More]
Thrasos presents positive results of THR-184 compound for treatment of acute kidney injury

Thrasos presents positive results of THR-184 compound for treatment of acute kidney injury

Thrasos Therapeutics, a biotherapeutics company focused on delivering new solutions for kidney disease, today presented preclinical results showing that its lead development compound THR-184 can effectively protect against loss of kidney function following acute ischemic injury in rat. [More]
Syngene International, Bristol-Myers Squibb extend drug discovery and development collaboration

Syngene International, Bristol-Myers Squibb extend drug discovery and development collaboration

Bristol-Myers Squibb and Syngene International, India's largest contract research organization, today announced a five-year extension of their drug discovery and development collaboration in India. [More]