Toxicology News and Research RSS Feed - Toxicology News and Research

Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.
Newborns of mothers who smoke during pregnancy have altered stress hormones, DNA

Newborns of mothers who smoke during pregnancy have altered stress hormones, DNA

Researchers from The Miriam Hospital have studied the effects of smoking during pregnancy and its impact on the stress response in newborn babies. Their research indicates that newborns of mothers who smoke cigarettes during pregnancy show lower levels of stress hormones, lowered stress response, and alterations in DNA for a gene that regulates passage of stress hormones from mother to fetus. [More]
Researchers discover new signaling pathway to fight excess body weight

Researchers discover new signaling pathway to fight excess body weight

The number of overweight persons is greatly increasing worldwide - and as a result is the risk of suffering a heart attack, stroke, diabetes or Alzheimer's disease. [More]
Intake of arsenic linked to cardiovascular disease, diabetes

Intake of arsenic linked to cardiovascular disease, diabetes

Associated with various types of cancer such as skin and liver, the intake of arsenic it is also linked to cardiovascular disease and diabetes. According to a long-term research conducted by experts from the Center for Research and Advanced Studies it was determined that this metalloid inhibits enzymes associated with antioxidant protection. [More]
Study reveals inner workings of PKA switch that regulates cellular functions, contributes to deadly disorders

Study reveals inner workings of PKA switch that regulates cellular functions, contributes to deadly disorders

A University of Utah-led study using X-rays and neutron beams has revealed the inner workings of a master switch that regulates basic cellular functions, but that also, when mutated, contributes to cancer, cardiovascular disease and other deadly disorders. [More]
Blocking STAT3 in immune system cells increases anti-tumour immunity

Blocking STAT3 in immune system cells increases anti-tumour immunity

The STAT transcription factors are involved in the development of many forms of cancer. STAT3 is frequently activated in tumour cells, so drugs targeting STAT3 could be used in cancer therapy. However, STAT3 is also important in the development of the immune system. Dagmar Gotthardt and colleagues at the Vetmeduni Vienna now show that blocking STAT3 in cells of the immune system actually leads to increased anti-tumour immunity. Anti-STAT3 therapy may thus be highly promising. [More]
Researchers reveal new information about Protein Kinase A

Researchers reveal new information about Protein Kinase A

Using X-rays and neutron beams, a team of researchers from the University of California, San Diego School of Medicine, University of Utah and Oak Ridge National Laboratory have teased out new information about Protein Kinase A (PKA), a ubiquitous master switch that helps regulate fundamental cellular functions like energy consumption and interactions with hormones, neurotransmitters and drugs. [More]
VCU receives $6 million grant to develop safe, effective treatments for cocaine addiction

VCU receives $6 million grant to develop safe, effective treatments for cocaine addiction

Virginia Commonwealth University has received a five-year, $6 million grant for clinical research and education directed toward the identification, evaluation and development of safe and effective treatments for cocaine addiction. [More]
Research!America to recognize distinguished research advocates with Advocacy Awards

Research!America to recognize distinguished research advocates with Advocacy Awards

Research!America's 19th annual Advocacy Awards will honor distinguished research advocates who are trailblazers in advancing medical progress to improve the health and economic security of our nation. The event will take place on Wednesday, March 11, 2015, at the Andrew W. Mellon Auditorium in Washington, DC. [More]
Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

Pitt researchers awarded new $5.8 million NIH grant to develop microfluidic 3D liver model system

With a new $5.8 million, three-year award from the National Institutes of Health, researchers at the University of Pittsburgh School of Medicine will further develop a state-of-the-art, microfluidic 3D model system that mimics structure and function of the liver to better predict organ physiology, assess drug toxicity and build disease models. [More]

Prioritizing scientific research to understand risks of PPCPs in the environment

In 2011 the Society of Environmental Toxicology and Chemistry held a workshop for 45 international experts to identify and prioritize the scientific research needed to understand the risks of pharmaceuticals and personal care products (PPCPs) in the environment. [More]
Adding common epilepsy drug to morphine can result in better pain control, say IU researchers

Adding common epilepsy drug to morphine can result in better pain control, say IU researchers

Adding a common epilepsy drug to a morphine regimen can result in better pain control with fewer side effects. Moreover, the combination can reduce the dosage of the opioid needed to be effective, according to a team of pain researchers at Indiana University. [More]
Zebrafish may hold key to unlocking a leading cause of respiratory diseases

Zebrafish may hold key to unlocking a leading cause of respiratory diseases

A small freshwater fish found in many tropical aquariums may hold the key to unlocking one of the leading causes of respiratory diseases in humans. [More]
Complete analysis of the global stem cell market

Complete analysis of the global stem cell market

BCC Research reveals in its new report, THE GLOBAL MARKET FOR STEM CELLS, the global market for stem cells is expected to grow to nearly $10.6 billion by 2018, with a five-year compound annual growth rate (CAGR) of 13.6%. [More]
New project aims at delivering innovative test to improve safety of chemical products, drugs

New project aims at delivering innovative test to improve safety of chemical products, drugs

The Genotrace project, combining targeted research and technology transfer, aims at delivering an innovative test to improve the safety of chemical products, drugs, human and animal food and the environment. [More]

Scanning electron microscope for 3D volume imaging of cells and tissues announced by FEI

FEI (NASDAQ: FEIC) announced today its new Teneo VS™ scanning electron microscope (SEM), which offers a VolumeScope™ capability for life science applications. The Teneo platform tightly integrates FEI’s latest-generation SEM with VolumeScope, an in-chamber microtome and proprietary analytical software to provide fully-automated, large-volume reconstructions with dramatically improved z-axis resolution. [More]
ANP reports primary efficacy results from ATL1103 Phase II trial in patients with acromegaly

ANP reports primary efficacy results from ATL1103 Phase II trial in patients with acromegaly

Antisense Therapeutics Limited is pleased to report the primary efficacy results from its Phase II clinical trial of ATL1103 in patients with the potentially life threatening growth disorder, acromegaly. [More]
Synthetic announces positive results from final preclinical toxicology study of SYN-004

Synthetic announces positive results from final preclinical toxicology study of SYN-004

Synthetic Biologics, Inc., a developer of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and diseases, announced today positive results from its final preclinical toxicology study of SYN-004. [More]
Ames test successfully adapted for use with cigarette smoke and other complex aerosols

Ames test successfully adapted for use with cigarette smoke and other complex aerosols

The Ames test, a widely used method to determine whether a chemical has the potential to cause cancer, has been successfully adapted for use with cigarette smoke and other complex aerosols. [More]
New mouse model to open door to research on epilepsy, Alzheimer's

New mouse model to open door to research on epilepsy, Alzheimer's

University of Utah scientists have developed a genetically engineered line of mice that is expected to open the door to new research on epilepsy, Alzheimer's and other diseases. [More]
VCU receives federal grant totaling $6.9 million to study genetics of alcohol abuse

VCU receives federal grant totaling $6.9 million to study genetics of alcohol abuse

Virginia Commonwealth University has received a federal grant totaling $6.9 million to study the genetics of alcohol abuse and alcoholism - work that may lead to further advances in its treatment, control and prevention. [More]