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Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.
Pre-birth arsenic exposure associated with early puberty, obesity in mice

Pre-birth arsenic exposure associated with early puberty, obesity in mice

Female mice exposed in utero, or in the womb, to low levels of arsenic through drinking water displayed signs of early puberty and became obese as adults, according to scientists from the National Institutes of Health. [More]
Energy-burning 'good' fat helps reduce weight gain, lower blood glucose levels in mice

Energy-burning 'good' fat helps reduce weight gain, lower blood glucose levels in mice

Scientists at the University of California, Berkeley, have developed a novel way to engineer the growth and expansion of energy-burning "good" fat, and then found that this fat helped reduce weight gain and lower blood glucose levels in mice. [More]
Penn State College of Medicine students to work with medical educators to design new curriculum

Penn State College of Medicine students to work with medical educators to design new curriculum

The medical school model that has existed for decades involves two years of study in the basic sciences followed by two years of clinical study. An initiative under way at Penn State College of Medicine will involve students in developing a new curriculum that integrates the two areas of study, with a goal of preparing physicians for the new realities of health care. [More]
Palatin applauds FDA's approval of flibanserin for women living with hypoactive sexual desire disorder

Palatin applauds FDA's approval of flibanserin for women living with hypoactive sexual desire disorder

Palatin Technologies, Inc. is a biopharmaceutical company developing targeted, receptor-specific peptide therapeutics for the treatment of diseases with significant unmet medical needs and commercial potential. Palatin's lead product under development is bremelanotide for the treatment of female sexual dysfunction (FSD). [More]
NanoViricides speeds up HerpeCide drug development program

NanoViricides speeds up HerpeCide drug development program

NanoViricides, Inc., a nanomedicine company developing anti-viral drugs, reports that it is accelerating its HerpeCide drug development program. [More]
Scientists partner to create liver-on-chip device that mimics human physiology

Scientists partner to create liver-on-chip device that mimics human physiology

Safety evaluation is a critical part of drug and cosmetic development. In recent years there is a growing understanding that animal experiments fail to predict the human response, necessitating the development of alternative models to predict drug toxicity. [More]
Kentucky researcher awarded NCI grant to study potential link between obesity and breast cancer

Kentucky researcher awarded NCI grant to study potential link between obesity and breast cancer

The National Cancer Institute recently awarded a $750,000 grant to University of Kentucky researcher Fredrick Onono to study the potential link between obesity and breast cancer. [More]
Alere supports DTHF’s Tutu Teen Truck project to expand reach of infectious services for youth

Alere supports DTHF’s Tutu Teen Truck project to expand reach of infectious services for youth

Alere Inc. (NYSE: ALR), a global leader in rapid diagnostics, today announced a grant of 2.5 million South African Rand to support the work of the Desmond Tutu HIV Foundation (DTHF), a Cape Town-based organization under the patronage of Archbishop Emeritus Desmond Tutu. [More]
Embryonic stem cells may help researchers to study physiological effects of environmental pollutants on human health

Embryonic stem cells may help researchers to study physiological effects of environmental pollutants on human health

A recent study published in the Journal of Environmental Sciences shows that embryonic stem cells could serve as a model to evaluate the physiological effects of environmental pollutants efficiently and cost-effectively. [More]
Roche establishes strategic alliance with Diagnostic Laboratory Services

Roche establishes strategic alliance with Diagnostic Laboratory Services

Roche announced today the establishment of a strategic alliance with Diagnostic Laboratory Services of Aiea, Hawaii, that designates the company as a Roche Molecular Center of Excellence (MCOE) for the next five years. [More]
15th Annual Geriatric Health Care Symposium now open for registration

15th Annual Geriatric Health Care Symposium now open for registration

Registration is now open for the 15th Annual Geriatric Health Care Symposium, "Maximizing Independence for Optimal Aging," presented by the University of Louisville Institute for Sustainable Health & Optimal Aging. [More]
Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

Novel 3D human skin tissue model could help detect presence of known skin sensitizers in medical device extracts

New research shows that exposing a 3D human skin tissue model to extracts of medical device materials can detect the presence of sensitizers known to cause an allergic response on contact in some individuals. Conventional skin sensitization testing of medical devices relies on animal testing, whereas human skin models could replace animal methods, according to an article in the new journal Applied In Vitro Toxicology, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers. [More]
RGS2 protein plays significant role in healthy egg-sperm union in mice

RGS2 protein plays significant role in healthy egg-sperm union in mice

Researchers at the National Institutes of Health have discovered a protein that plays a vital role in healthy egg-sperm union in mice. The protein RGS2 can delay an egg's development into an embryo in order to allow time for sperm to arrive and merge with the egg in a healthy fertilization process. The embryo cannot survive without the male chromosomes. [More]
Innovative approach to treating AAT deficiency

Innovative approach to treating AAT deficiency

Researchers have demonstrated the feasibility of delivering an RNA that encodes for the protein alpha-1-antitrypsin (AAT)--which is missing or nonfunctional in the genetic disorder AAT deficiency--into cells in the laboratory, enabling the cells to produce highly functional AAT. [More]
Researchers decode molecular mechanism of fish toxin that has potential to treat cancer

Researchers decode molecular mechanism of fish toxin that has potential to treat cancer

Pathogenic bacteria develop killer machines that work very specifically and highly efficiently. Scientists from the University of Freiburg have solved the molecular mechanism of a fish toxin that could be used in the future as a medication to treat cancer. The scientists have now published their research in the journal Nature Communications. [More]
Dartmouth researchers perform first total syntheses of compounds involved in rapid cell death in leukemia

Dartmouth researchers perform first total syntheses of compounds involved in rapid cell death in leukemia

Dartmouth researchers and their colleagues have carried out the first total syntheses of certain compounds involved in excessive cell death in leukemia. [More]
Sulfur dioxide air pollutant can cause adverse effects in asthmatics

Sulfur dioxide air pollutant can cause adverse effects in asthmatics

Emissions of the air pollutant sulfur dioxide have been dramatically decreased during the past 30 years but for some people even a little inhaled sulfur dioxide may still be too much. [More]

Alere announces two transactions to further strengthen its core business strategy

Alere Inc., a global leader in rapid diagnostics, announced today two transactions that further strengthen the Company's focus on its core business strategy. [More]
FDA grants CLIA waiver for Alere i Strep A test

FDA grants CLIA waiver for Alere i Strep A test

Alere Inc., a global leader in rapid diagnostic tests, today announced that the U.S. Food and Drug Administration has granted CLIA waiver for the Alere i Strep A test. The test, which was cleared for marketing by the FDA in April 2015, is the first molecular platform that detects Group A Streptococcus (GAS) bacteria in 8 minutes or less. [More]
Novogen's Anisina granted FDA Orphan Drug Designation for neuroblastoma

Novogen's Anisina granted FDA Orphan Drug Designation for neuroblastoma

US-Australian drug discovery company, Novogen Limited, today announced that it has received notification from the U.S. Food and Drug Administration that its chemotherapy candidate drug, Anisina, has been granted Orphan Drug Designation for neuroblastoma. [More]
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