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Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.
Ames test successfully adapted for use with cigarette smoke and other complex aerosols

Ames test successfully adapted for use with cigarette smoke and other complex aerosols

The Ames test, a widely used method to determine whether a chemical has the potential to cause cancer, has been successfully adapted for use with cigarette smoke and other complex aerosols. [More]
New mouse model to open door to research on epilepsy, Alzheimer's

New mouse model to open door to research on epilepsy, Alzheimer's

University of Utah scientists have developed a genetically engineered line of mice that is expected to open the door to new research on epilepsy, Alzheimer's and other diseases. [More]
VCU receives federal grant totaling $6.9 million to study genetics of alcohol abuse

VCU receives federal grant totaling $6.9 million to study genetics of alcohol abuse

Virginia Commonwealth University has received a federal grant totaling $6.9 million to study the genetics of alcohol abuse and alcoholism - work that may lead to further advances in its treatment, control and prevention. [More]
Research findings may lead to novel target for chemoresistant cancer cells

Research findings may lead to novel target for chemoresistant cancer cells

Dartmouth cancer researchers at Norris Cotton Cancer Center found a means of causing the elimination of a protein that maintains cancer cell viability; the results of the study appear in the August 8 issue of The Journal of Biological Chemistry. [More]
Researchers develop new lung-on-chip model for laboratory studies of respiratory challenges

Researchers develop new lung-on-chip model for laboratory studies of respiratory challenges

Researchers at RTI International, in collaboration with the University of North Carolina at Chapel Hill, have developed a new lung-on-chip microdevice for laboratory studies of respiratory challenges and therapeutics. The microdevice includes multiple vertically stacked cellular layers that mimic the structure of the airway tissue. [More]

Cerilliant offers nine new stable isotope-labeled internal standards of 2C amines

Sigma-Aldrich Corporation is pleased to announce that the Cerilliant® brand within its Applied Diagnostics and Testing business segment now offers nine new stable isotope-labeled internal standards of 2C amines including deuterium and 13C labeling. [More]
2 active ingredients in household cleaning products cause declines in mouse reproduction

2 active ingredients in household cleaning products cause declines in mouse reproduction

Virginia Tech researchers who were using a disinfectant when handling mice have discovered that two active ingredients in it cause declines in mouse reproduction. [More]
Expert panel issues key suggestions related to unconventional natural gas drilling operations

Expert panel issues key suggestions related to unconventional natural gas drilling operations

Groundwater and air quality testing before, during, and after natural gas drilling - which includes hydraulic fracturing -- should be key components of efforts to ensure the safety of communities near these sites, according to an expert panel convened to weigh in on public health research needs associated with unconventional natural gas drilling operations (UNGDO). [More]
CAP awards accreditation to The Children's Hospital of Philadelphia Pathology & Laboratory Medicine

CAP awards accreditation to The Children's Hospital of Philadelphia Pathology & Laboratory Medicine

The Accreditation Committee of the College of American Pathologists (CAP) has awarded accreditation to The Children's Hospital of Philadelphia Pathology & Laboratory Medicine, Philadelphia, Pennsylvania based on results of a recent on-site inspection as part of the CAP's Accreditation Programs. [More]
Opioid compliance checklist shows promise for chronic pain management

Opioid compliance checklist shows promise for chronic pain management

Researchers have developed a brief and simple checklist that clinicians can use to monitor opioid adherence among people with chronic pain. [More]
Vitro toxicity testing an alternative to predict adverse health effects of drugs

Vitro toxicity testing an alternative to predict adverse health effects of drugs

In vitro toxicity testing is rapidly being adopted in the pharmaceutical, chemical, and cosmetics industries, for example, as an alternative to animal studies to predict adverse health effects of drugs and personal care products and the health consequences of environmental exposures. [More]
Repurposed drug used to treat ovarian cancer gives positive results

Repurposed drug used to treat ovarian cancer gives positive results

A repurposed drug originally used to treat ovarian cancer saw positive results for patients with advanced peritoneal cancers during a phase I clinical trial at The University of Kansas Cancer Center. [More]
Alere announces financial results for quarter ended 2014

Alere announces financial results for quarter ended 2014

Alere Inc., a global leader in rapid diagnostics and health information solutions, today announced its financial results for the quarter ended June 30, 2014. [More]
Nicotine, cotinine can potentially inhibit DNA damage caused by NNK in tobacco smoke

Nicotine, cotinine can potentially inhibit DNA damage caused by NNK in tobacco smoke

A new in vitro study has revealed that nicotine and cotinine, a metabolite of nicotine, can potentially inhibit DNA damage caused by a certain carcinogen in smoke. [More]
Randox expands major supplier agreement with Novation

Randox expands major supplier agreement with Novation

Randox Laboratories has further expanded its market presence in the United States, having been awarded a major supplier agreement with Novation, the leading health care supply chain expertise, analytics and contracting company. [More]
RX daytona+ provides high quality testing on compact easy to use platform

RX daytona+ provides high quality testing on compact easy to use platform

Randox has developed a versatile range of clinical chemistry analyzers with real cost saving in mind. The RX series of clinical chemistry analyzers provides performance like no other. [More]
Randox's Acusera Immunoassay Speciality 1 quality control receives FDA clearance

Randox's Acusera Immunoassay Speciality 1 quality control receives FDA clearance

In Q3 of 2013, Randox announced that the Food and Drug Administration has approved the company's Acusera Immunoassay Speciality 1 quality control for use in US laboratories. [More]
Research highlights potential cancer risk in non-smokers

Research highlights potential cancer risk in non-smokers

Research led by the University of York has highlighted the potential cancer risk in non-smokers - particularly young children - of tobacco smoke gases and particles deposited to surfaces and dust in the home. [More]
Baxter International acquires drug candidate developed to treat sickle cell disease

Baxter International acquires drug candidate developed to treat sickle cell disease

A drug candidate developed by researchers at the NIH's National Center for Advancing Translational Sciences and its collaborators to treat sickle cell disease has been acquired by Baxter International's BioScience business. [More]
Mice exposed to low doses of arsenic in drinking water develop lung cancer

Mice exposed to low doses of arsenic in drinking water develop lung cancer

Mice exposed to low doses of arsenic in drinking water, similar to what some people might consume, developed lung cancer, researchers at the National Institutes of Health have found. [More]