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Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.
P2Y12 and blood clotting: an interview with Dr. Jacobson, NIH

P2Y12 and blood clotting: an interview with Dr. Jacobson, NIH

We already understand the many steps involved in blood clotting in great mechanistic detail. The process of blood vessels closing off in response to injury is necessary for preserving life, but blood platelets that are over-active, or activated inappropriately because of unstable plaque, can lead to heart attacks and strokes. [More]
Compound in saliva may protect from toxins in tea, coffee and liquid smoke flavoring

Compound in saliva may protect from toxins in tea, coffee and liquid smoke flavoring

A compound in saliva, along with common proteins in blood and muscle, may protect human cells from powerful toxins in tea, coffee and liquid smoke flavoring, according to results of a new study led by investigators at the Johns Hopkins Kimmel Cancer Center. [More]
Compound in saliva and proteins in blood may protect human cells from powerful toxins in tea, coffee

Compound in saliva and proteins in blood may protect human cells from powerful toxins in tea, coffee

A compound in saliva, along with common proteins in blood and muscle, may protect human cells from powerful toxins in tea, coffee and liquid smoke flavoring, according to results of a new study led by investigators at the Johns Hopkins Kimmel Cancer Center. [More]
Researchers find link between aging and chemicals in environment

Researchers find link between aging and chemicals in environment

Why are some 75-year-olds downright spry while others can barely get around? Part of the explanation, say researchers writing in the Cell Press journal Trends in Molecular Medicine on May 28, is differences from one person to the next in exposure to harmful substances in the environment, chemicals such as benzene, cigarette smoke, and even stress. [More]
The future of high throughput screening: an interview with Mark Wigglesworth, Director High Throughput Screening, AstraZeneca

The future of high throughput screening: an interview with Mark Wigglesworth, Director High Throughput Screening, AstraZeneca

Quoting Mike Snowden (VP & Head of Discovery Sciences, AstraZeneca), “it’s where biology meets chemistry”. It’s where for the first time a target protein can be probed for novel molecules that modulate its function, of course we want to do this to prove a hypothesis that these proteins are drug targets with the potential to deliver innovative medicines. [More]
UH pharmacy students earn awards for excellence in leadership, professional service and clinical skills from TSHP

UH pharmacy students earn awards for excellence in leadership, professional service and clinical skills from TSHP

University of Houston (UH) pharmacy students wrapped up the spring semester with a round of awards for excellence in leadership, professional service and clinical skills. [More]
Tel Aviv University pinpoints mechanism that causes rare and severe congenital syndrome

Tel Aviv University pinpoints mechanism that causes rare and severe congenital syndrome

In the 1950s and 1960s, pregnant women with morning sickness were often prescribed the new drug thalidomide. Shortly after the medicine was released on the market, a reported 10,000 infants were born with an extreme form of the rare congenital phocomelia syndrome, which caused death in 50 percent of cases and severe physical and mental disabilities in others. [More]
£1.5M research funding aims to extend imaging techniques, reduce animal use in preclinical research

£1.5M research funding aims to extend imaging techniques, reduce animal use in preclinical research

£1.5m of research funding has been awarded to develop advanced imaging technologies, to maximise their potential to reduce animal use in a diverse range of preclinical research applications. [More]
Hormone disrupting pollutants affecting the development of wild birds along urban rivers

Hormone disrupting pollutants affecting the development of wild birds along urban rivers

New research indicates that hormone disrupting pollutants are affecting the health and development of wild birds nesting along the urban rivers of South Wales. [More]
Alere reports net revenue of $716.6 million for first quarter 2014

Alere reports net revenue of $716.6 million for first quarter 2014

Alere Inc., a global leader in enabling individuals to take charge of their health at home through the merger of rapid diagnostics and health information solutions, today announced its financial results for the quarter ended March 31, 2014. [More]
Anaphylaxis Campaign's special conference to explore issues in allergy care

Anaphylaxis Campaign's special conference to explore issues in allergy care

This special conference for our 20th Anniversary year will focus on providing a full and comprehensive round up of past, present and emerging themes and trends in allergy, care and management. The conference is free to all our Healthcare Professional Members and we are expecting over 70 clinicians in the field of allergy to attend. [More]
UTMB awarded $6.6 million grant to establish Translational Addiction Sciences Center

UTMB awarded $6.6 million grant to establish Translational Addiction Sciences Center

The National Institute on Drug Abuse has awarded a five-year, $6.6 million grant to the University of Texas Medical Branch at Galveston to establish the Translational Addiction Sciences Center. The center will investigate the mechanisms underlying addiction with the goal of discovering and validating novel treatment options. [More]
Discovery offers potential target for reversing progression of end-stage liver disease

Discovery offers potential target for reversing progression of end-stage liver disease

A team of researchers in the University of Arizona's College of Pharmacy has discovered a molecular pathway that could be key to creating new therapeutics that would slow or even reverse the progression of end-stage liver disease. [More]

UB research finds novel compound for treating cocaine addiction

A novel compound that targets an important brain receptor has a dramatic effect against a host of cocaine addiction behaviors, including relapse behavior, a University at Buffalo animal study has found. [More]
Study reveals antibacterial agent triclosan promotes growth of human breast cancer cells in lab dishes

Study reveals antibacterial agent triclosan promotes growth of human breast cancer cells in lab dishes

Some manufacturers are turning away from using triclosan as an antimicrobial ingredient in soaps, toothpastes and other products over health concerns. [More]
Genoa Pharmaceuticals, McMaster University report additional benefits of GP-101 for IPF patients

Genoa Pharmaceuticals, McMaster University report additional benefits of GP-101 for IPF patients

Genoa Pharmaceuticals, the leader in inhaled medicines for pulmonary fibrosis, and collaborators Drs. Martin Kolb and Kjetil Ask at McMaster University announced today additional measured advantages of inhaled GP-101 (aerosol pirfenidone) in the treatment of idiopathic pulmonary fibrosis (IPF). [More]
Targeted Medical Pharma signs agreement with Lebanon based company, ATL

Targeted Medical Pharma signs agreement with Lebanon based company, ATL

Targeted Medical Pharma, today announced the completion of an agreement between Analytical Testing Laboratories (ATL), a Lebanon based company that specializes in drug testing services and inborn errors of metabolism, for the exclusive distribution of the company's amino acid based products to physicians and pharmacies throughout the Middle East. [More]
Freiburg researchers discover molecule that smuggles toxins from intestinal pathogens into human cells

Freiburg researchers discover molecule that smuggles toxins from intestinal pathogens into human cells

Prof. Dr. Dr. Klaus Aktories and Dr. Panagiotis Papatheodorou from the Institute of Experimental and Clinical Pharmacology and Toxicology of the University of Freiburg have discovered the receptor responsible for smuggling the toxin of the bacterium Clostridium perfringens into the cell. [More]
Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

Effects of PectaSol-C modified citrus pectin in prostate cancer patients to be studied in phase III trial

A phase III clinical trial conducted at the Meir Medical Center in Kfar-Saba, Israel is now recruiting participants to study the effects of dietary supplement PectaSol-C modified citrus pectin (MCP) in controlling prostate specific antigen (PSA) levels in prostate cancer patients. [More]
Experts and entrepreneurs to gather at 2014 Biotech China on 14-16 May

Experts and entrepreneurs to gather at 2014 Biotech China on 14-16 May

With just one month until 2014 Biotech China, experts, entrepreneurs and decision-makers from the international biotechnology industry will gather at the heart of the Chinese biotechnology industry on May 14-16th, 09:00 AM-06:00 PM in Nanjing China. [More]