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Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.

Role of biomarkers in drug development and regulatory decision making

Biomarkers in Medicine, a leading MEDLINE-indexed journal, has published a special focus issue exploring the increasingly important role of biomarkers in both drug development and regulatory decision making. [More]
Lead exposure in early childhood increases risk for sleep problems in later childhood

Lead exposure in early childhood increases risk for sleep problems in later childhood

A new research study from the University of Pennsylvania School of Nursing shows that lead exposure in early childhood are associated with increased risk for sleep problems and excessive daytime sleepiness in later childhood. [More]
New computational method helps predict adverse drug reaction better than traditional computing methods

New computational method helps predict adverse drug reaction better than traditional computing methods

A new integrated computational method helps predicting adverse drug reaction--which are often lethal--more reliably than with traditional computing methods. This improved ability to foresee the possible adverse effects of drugs may entail saving many lives in the future. [More]
Pittcon will exhibit at the Bioconference clinical diagnostics and research virtual conference

Pittcon will exhibit at the Bioconference clinical diagnostics and research virtual conference

Pittcon is pleased to announce its participation in the “Clinical Diagnostics & Research” virtual conference from November 11 to 12, 2015. Clinicians, researchers, medical experts, and professionals from around the world convene for this free web-conference to learn and interact with a community of like-minded colleagues. [More]
Lower doses of chemicals found in personal care products may contribute to breast cancer risk

Lower doses of chemicals found in personal care products may contribute to breast cancer risk

Estrogen-mimicking chemicals called parabens, which are commonly found in an array of personal care products, may be more dangerous at lower doses than previously thought, according to a new study. [More]
Orange pigment may have potential as anti-cancer drug

Orange pigment may have potential as anti-cancer drug

An orange pigment found in lichens and rhubarb called parietin may have potential as an anti-cancer drug, scientists at Winship Cancer Institute of Emory University have discovered. [More]
Nanodiamonds may improve outcomes for patients undergoing root canals

Nanodiamonds may improve outcomes for patients undergoing root canals

People undergoing root canals may have gained a powerful, if tiny, new ally. Researchers from the UCLA School of Dentistry have found that using nanodiamonds to fortify a material used in the procedure could significantly improve outcomes for patients. [More]
New research shows nicotine increases codeine-induced analgesia

New research shows nicotine increases codeine-induced analgesia

According to new research in rat models, nicotine use over time increases the speed that codeine is converted into morphine within the brain, by increasing the amount of a specific enzyme. It appears smokers' brains are being primed for a bigger buzz from this common pain killer - which could put them at a higher risk for addiction, and possibly even overdose. [More]
Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Researchers from Isis Pharmaceuticals (Carlsbad, CA) and Prysis Biotechnologies (Pudong, Shanghai, China) have demonstrated proof-of-concept for using a sense oligonucleotide to undo the effects of an antisense drug, an antithrombotic agent in this novel study. [More]
Frost & Sullivan recognizes hc1.com with 2015 North American Award for Product Leadership

Frost & Sullivan recognizes hc1.com with 2015 North American Award for Product Leadership

Based on its recent analysis of the use of customer relationship management (CRM) solutions in the $70 billion US diagnostic laboratory market, Frost & Sullivan recognizes hc1.com with its 2015 North American Award for Product Leadership. [More]
Alere doubles commitment to support OAFLA in eliminating mother-to-child transmission of HIV and EID

Alere doubles commitment to support OAFLA in eliminating mother-to-child transmission of HIV and EID

Alere, a global leader in rapid diagnostics, today doubled its commitment to the Organisation of African First Ladies Against HIV/AIDS in its efforts to reduce the impact of HIV/AIDS in Africa by eliminating mother-to-child transmission of HIV and increasing early infant diagnosis (EID). [More]
Kolltan announces presentation of data from KTN0158 preclinical study in mast cell tumors at ESMO 2015

Kolltan announces presentation of data from KTN0158 preclinical study in mast cell tumors at ESMO 2015

Kolltan Pharmaceuticals, Inc. today announced the presentation of data from a preclinical study evaluating KTN0158 in dogs with spontaneous mast cell tumors. KTN0158 is a proprietary, humanized anti-KIT IgG1 monoclonal antibody drug candidate being developed as a potential therapy for cancer and mast cell-related diseases. [More]
Study reports use of new psychoactive drugs in US nationally representative survey

Study reports use of new psychoactive drugs in US nationally representative survey

In recent years, there has been an increase in emergence and use of a variety of new drugs, so-called "novel psychoactive substances" (NPS) in the US and worldwide. [More]

Cerilliant offers first-ever multi-component solutions for qualitative evaluation of drug interference

Sigma-Aldrich Corporation today announced that the Cerilliant® brand within its Applied Diagnostics and Testing business segment now offers the first-ever reference solutions for qualitative evaluation of drug interferences in a testing laboratory's analytical methods. [More]
Inhibition of Tyk2 enzyme promotes anti-cancer activity

Inhibition of Tyk2 enzyme promotes anti-cancer activity

Tyrosine kinase 2 (Tyk2) is an enzyme involved in intracellular signalling and has an important role in activating the immune system. [More]
Researchers take new line of approach to combat Alzheimer's disease

Researchers take new line of approach to combat Alzheimer's disease

Today, more than 5.1 million Americans live with Alzheimer's disease, a devastating type of dementia that plagues memory and thinking. That number is expected to triple in the coming decades. Moreover, according to a 2012 survey, Americans fear Alzheimer's more than any other disease. [More]

Alere announces cash dividend of $3.00 per share on Series B Convertible Perpetual Preferred Stock

Alere Inc., a global leader in rapid diagnostics, today has declared a cash dividend of $3.00 per share on its Series B Convertible Perpetual Preferred Stock (NYSE: ALR.PR.B). [More]
Pre-birth arsenic exposure associated with early puberty, obesity in mice

Pre-birth arsenic exposure associated with early puberty, obesity in mice

Female mice exposed in utero, or in the womb, to low levels of arsenic through drinking water displayed signs of early puberty and became obese as adults, according to scientists from the National Institutes of Health. [More]
Energy-burning 'good' fat helps reduce weight gain, lower blood glucose levels in mice

Energy-burning 'good' fat helps reduce weight gain, lower blood glucose levels in mice

Scientists at the University of California, Berkeley, have developed a novel way to engineer the growth and expansion of energy-burning "good" fat, and then found that this fat helped reduce weight gain and lower blood glucose levels in mice. [More]
Penn State College of Medicine students to work with medical educators to design new curriculum

Penn State College of Medicine students to work with medical educators to design new curriculum

The medical school model that has existed for decades involves two years of study in the basic sciences followed by two years of clinical study. An initiative under way at Penn State College of Medicine will involve students in developing a new curriculum that integrates the two areas of study, with a goal of preparing physicians for the new realities of health care. [More]
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