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Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.
Study data does not support benefits of testosterone supplementation in men with ‘low T’

Study data does not support benefits of testosterone supplementation in men with ‘low T’

The prescription of testosterone supplementation for cardiovascular health, sexual function, physical function, mood, or cognitive function in men with "low T" is not supported by clinical trials data, conclude researchers who describe a review of more than 200 clinical trials published Sept. 21 in PLOS One. [More]
Texas A&M research shows nicotine could help protect the aging brain

Texas A&M research shows nicotine could help protect the aging brain

Everyone knows that tobacco products are bad for your health, and even the new e-cigarettes may have harmful toxins. [More]
UofL investigators to explore liver disease in comprehensive fashion

UofL investigators to explore liver disease in comprehensive fashion

Liver diseases are clinically important health problems and are generally underappreciated. The University of Louisville has brought together a critical mass of investigators to study liver diseases in a comprehensive fashion. [More]
New study raises safety concerns on clinical use of caspase inhibitors for liver diseases

New study raises safety concerns on clinical use of caspase inhibitors for liver diseases

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase. Caspase inhibitors have therapeutic potential to treat and prevent apoptosis-mediated liver injury, and some are currently in clinical trials. [More]
NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Researchers at the National Center for Advancing Translational Sciences recently identified compounds that potentially can be used to inhibit Zika virus replication and reduce its ability to kill brain cells. [More]
Study finds link between childhood manganese exposure and attentional dysfunction in rodent model

Study finds link between childhood manganese exposure and attentional dysfunction in rodent model

Researchers using a rodent model of childhood manganese exposure have found that too much manganese early in development causes lasting attention deficits and other impairments. [More]
UCLA study suggests lower BPS doses damage woman's egg cells

UCLA study suggests lower BPS doses damage woman's egg cells

Bisphenol S, a chemical used to manufacture polycarbonate water bottles and many other products such as epoxy glues and cash receipts, is an increasingly common replacement for bisphenol A, the of which was discontinued because of concerns about its harmful effects on the reproductive system. [More]
Reproductive age-related changes in ovarian environment may contribute to infertility

Reproductive age-related changes in ovarian environment may contribute to infertility

Women's decreased ability to produce healthy eggs as they become older may be due to excessive scarring and inflammation in their ovaries, reports a new Northwestern Medicine study in mice. [More]
Study finds high rate of misuse of seizure and pain drug

Study finds high rate of misuse of seizure and pain drug

With increasing public attention to overdose deaths and misuse of prescription medications in the United States, researchers today presented the results of a new study looking at abuse and misuse of gabapentin, a medication used to treat seizures and relieve nerve pain often associated with shingles. [More]
Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Many gene mutations that cause neurological disorders have been identified. For example, in a rare neurological disorder such as Huntington’s disease, an autosomal dominant mutation through expansion of CAG (cytosine-adenine-guanine) triplet repeats in the gene coding for the Huntingtin protein results in abnormal protein production. [More]
AACC 2016: DRG International to exhibit Optimized Saliva ELISA Assays for measuring steroids

AACC 2016: DRG International to exhibit Optimized Saliva ELISA Assays for measuring steroids

DRG International, a leading international medical diagnostic company, will showcase the Newly Optimized DRG Saliva ELISA Assays at the 2016 AACC in Philadelphia, Pennsylvania from August 02-04. [More]
DRG International to display Hepcidin 25 (bioactive) HS ELISA Kit at 2016 AACC Expo

DRG International to display Hepcidin 25 (bioactive) HS ELISA Kit at 2016 AACC Expo

DRG International, a leading international medical diagnostic company, will showcase the NEW DRG Hepcidin 25 (bioactive) HS (High Sensitive) ELISA Kit (EIA-5782) at the 2016 AACC in Philadelphia, Pennsylvania from August 02-04. [More]
DRG International to present Aldosterone ELISA Kit at 2016 AACC

DRG International to present Aldosterone ELISA Kit at 2016 AACC

DRG International, a leading international medical diagnostic company, will showcase its DRG Aldosterone ELISA Kit at the 2016 AACC in Philadelphia, Pennsylvania on August 02-04. [More]
Express Diagnostics Int'l announces start of operations at new subsidiary in Bulgaria

Express Diagnostics Int'l announces start of operations at new subsidiary in Bulgaria

Express Diagnostics Int'l, Inc., FDA-registered and ISO 13485:2003-certified medical device manufacturer, announces Express Diagnostics Global, Ltd., a new subsidiary based in Sofia, Bulgaria is operational. [More]
Majority of American adults use prescription drugs inappropriately and dangerously

Majority of American adults use prescription drugs inappropriately and dangerously

The majority of American adults taking opioids and other commonly prescribed medications use them in ways that put their health at risk, including potentially dangerous combinations with other drugs, according to a new study from Quest Diagnostics, the world’s leading provider of diagnostic information services. [More]
Researchers find genetic variability in frozen vials of cells purchased from same cell bank

Researchers find genetic variability in frozen vials of cells purchased from same cell bank

In a surprise finding, researchers working with breast cancer cells purchased at the same time from the same cell bank discovered that the cells responded differently to chemicals, even though the researchers had not detected any difference when they tested them for authenticity at the time of purchase. [More]
Novel community-produced biological network models hold potential in drug discovery and toxicology

Novel community-produced biological network models hold potential in drug discovery and toxicology

A new set of community-produced biological network models has been shown to allow a deeper understanding of the mechanisms underlying a range of diseases. [More]
Predictive power of computational toxicology demonstrated with crowd-sources scientific challenge

Predictive power of computational toxicology demonstrated with crowd-sources scientific challenge

Results of the Systems Toxicology Computational Challenge have demonstrated how transcriptomics information present in the blood can be used to predict whether people have been exposed or not exposed to specific toxicants. [More]
New multicomponent reactions to develop active compounds against sleeping sickness

New multicomponent reactions to develop active compounds against sleeping sickness

Multicomponent reactions are protocols that ease the chemical synthesis of new compounds, and are particularly important to gain molecules with biological activity as therapeutic agents against several pathogens. [More]
Researchers make successful vaccine formulation that targets proteins linked to Alzheimer’s disease

Researchers make successful vaccine formulation that targets proteins linked to Alzheimer’s disease

With more than 7.5 million new cases of Alzheimer’s disease a year, the race to find a vaccine and effective treatment for dementia is growing by the day. [More]
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