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RNA-binding protein ROQUIN regulates response to DNA damage

Messenger (mRNA) molecules are a key component of protein biosynthesis. They are first transcribed as a "working copy" of the DNA and then translated into protein molecules.

3 Aug 2015

Sorrento to develop and market monoclonal antibodies for North American, European and Japanese market

Sorrento Therapeutics, Inc. announced today that it has entered into an exclusive licensing agreement to develop and commercialize multiple prespecified and undisclosed biosimilar or biobetter antibodies from Mabtech Limited, a holding company for premier antibody development and manufacturing companies in China.

3 Aug 2015

Isis Pharmaceuticals, AstraZeneca to develop antisense therapies for cardiovascular, metabolic, renal diseases

AstraZeneca and Isis Pharmaceuticals, Inc. today announced a strategic collaboration to discover and develop antisense therapies for cardiovascular, metabolic and renal diseases.

3 Aug 2015

New MS therapies associated with risks and side effects, require active management strategy

Advances in the treatment of Multiple Sclerosis have been good news for patients, but side effects and risks mean that an active management strategy and constant monitoring are essential.

3 Aug 2015

BUSM researchers find new way to detect and treat basal-like breast cancer

A new way to detect - and perhaps treat - one of the deadliest types of breast cancer has been found. Led by researchers at Boston University School of Medicine (BUSM), the study appears online in Breast Cancer Research.

3 Aug 2015

Researchers quantify growth and composition of breast tumours in living animal

The ability to visualize and characterize the composition of a tumour in detail during its development can provide valuable insights in order to target appropriate therapeutics.

3 Aug 2015

Brain-controlled prosthesis could improve quality of life in people with spinal cord injuries

When we type or perform other precise tasks, our brains and muscles usually work together effortlessly. But when a neurological disease or spinal cord injury severs the connection between the brain and limbs, once-easy motions become difficult or impossible.

3 Aug 2015

High levels of specific proteins in urine can accurately detect early-stage pancreatic cancer

A combination of three proteins found at high levels in urine can accurately detect early-stage pancreatic cancer, UK researchers have found.

3 Aug 2015

New method helps determine titanium nanoparticles in sunscreen products

Loads of cosmetics like sunscreen lotions contain titanium dioxide. These nanoparticles are contentious. Experts suspect they may have harmful effects on people and the environment.

3 Aug 2015

Environmental factors promote genetic mutations, have underappreciated effect on disease, evolution

Washington State University researchers say environmental factors are having an underappreciated effect on the course of disease and evolution by prompting genetic mutations through epigenetics, a process by which genes are turned on and off independent of an organism's DNA sequence.

3 Aug 2015

Researchers closer to understanding complicated brain chemistry behind Alzheimer's disease

Researchers at the University of Melbourne have discovered that a protein involved in the progression of Alzheimer's disease also has properties that could be helpful for human health.

3 Aug 2015

Redox equilibrium may help identify new diagnostic biomarkers for ageing, neurodegenerative processes

The question of why we age is one of the most fascinating questions for humankind, but nothing close to a satisfactory answer has been found to date.

3 Aug 2015

Atomic level images reveal how neuropeptide hormone neurotensin may activate its receptors

Many hormones and neurotransmitters work by binding to receptors on a cell's exterior surface. This activates receptors causing them to twist, turn and spark chemical reactions inside cells.

3 Aug 2015

Childhood cancer cells produce molecule that affects body's immune system to fight disease

Cancer cells in neuroblastoma contain a molecule that breaks down a key energy source for the body's immune cells, leaving them too physically drained to fight the disease, according to new research published in the journal Cancer Research today (Saturday).

3 Aug 2015

University of Southampton research finds that electric fields alter behaviour of fruit flies

A new piece of research led by the University of Southampton has found that the behaviour of fruit flies, which are commonly used in laboratory experiments, is altered by electric fields.

31 Jul 2015

Reducing incorrect gene expression can extend lifespan of cells

Working with yeast and worms, researchers found that incorrect gene expression is a hallmark of aged cells and that reducing such "noise" extends lifespan in these organisms. The team published their findings this month in Genes & Development.

31 Jul 2015

Scientists chemically synthesize ECA-derived oligosaccharides relevant for immunotherapy

Immunotherapy using monoclonal antibodies is a promising treatment strategy, and it might now be within reach: American scientists have successfully prepared an oligosaccharide enterobacterial antigen for which a monoclonal antibody has been developed. The study is published in the journal Angewandte Chemie.

31 Jul 2015

Researchers gain new insight into the stages of breast cancer growth

The ability to visualize and characterize the composition of a tumour in detail during its development can provide valuable insights in order to target appropriate therapeutics. The polymer chemist Prof. Dr. Prasad Shastri and the pharmacist Jon Christensen, in collaboration with the biomedical researcher Dr. Daniel Vonwil, from the University of Freiburg have visualized and quantified the growth and composition of breast tumours over time in a living animal.

31 Jul 2015

Taiwanese scientists propose advanced solution that can be applied to thermal cancer therapy

Precise targeting biological molecules, such as cancer cells, for treatment is a challenge, due to their sheer size. Now, Taiwanese scientists have proposed an advanced solution, based on a novel combination of previously used techniques, which can potentially be applied to thermal cancer therapy.

31 Jul 2015

BGI to hold 10th International Conference on Genomics in October

The 10th International Conference on Genomics (ICG-10) will be held by BGI from October 22-25, 2015, in Shenzhen, China.

31 Jul 2015

Medical Science News

RNA-binding protein ROQUIN regulates response to DNA damage

Sorrento to develop and market monoclonal antibodies for North American, European and Japanese market

Isis Pharmaceuticals, AstraZeneca to develop antisense therapies for cardiovascular, metabolic, renal diseases

New MS therapies associated with risks and side effects, require active management strategy

BUSM researchers find new way to detect and treat basal-like breast cancer

Researchers quantify growth and composition of breast tumours in living animal

Brain-controlled prosthesis could improve quality of life in people with spinal cord injuries

High levels of specific proteins in urine can accurately detect early-stage pancreatic cancer

New method helps determine titanium nanoparticles in sunscreen products

Environmental factors promote genetic mutations, have underappreciated effect on disease, evolution

Researchers closer to understanding complicated brain chemistry behind Alzheimer's disease

Redox equilibrium may help identify new diagnostic biomarkers for ageing, neurodegenerative processes

Atomic level images reveal how neuropeptide hormone neurotensin may activate its receptors

Childhood cancer cells produce molecule that affects body's immune system to fight disease

University of Southampton research finds that electric fields alter behaviour of fruit flies

Reducing incorrect gene expression can extend lifespan of cells

Scientists chemically synthesize ECA-derived oligosaccharides relevant for immunotherapy

Researchers gain new insight into the stages of breast cancer growth

Taiwanese scientists propose advanced solution that can be applied to thermal cancer therapy

BGI to hold 10th International Conference on Genomics in October

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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