Cellulite is thought to be common in most women. There appears to be a hormonal component to its presentation. It is rarely seen in males, and may involve changes in metabolism and physiology such as gender specific dimorphic skin architecture, alteration of connective tissue structure, vascular changes and inflammatory processes.
Hormonal factors
Hormones play a dominant role in the formation of cellulite. Estrogen may be the important hormone and initiate and aggravate cellulite. However, there has been no reliable clinical evidence to support such a claim. Other hormones including insulin, the catecholamines adrenaline and noradrenaline, thyroid hormones, and prolactin are all believed to participate in the development of cellulite. a hormone receptor allele that determines the receptor number and sensitivity, distribution of subcutaneous fat, and predisposition to circulatory insufficiency have all been shown to contribute to cellulite.
Lifestyle
A high stress lifestyle will cause an increase in the level of catecholamines, which have also been associated with the evolution of cellulite. Dr. Michael F. McGuire, a clinical associate professor at the David Geffen School of Medicine at the University of California, Los Angeles, confirmed that “realistically there is no cure for cellulite.”
The most beneficial therapy may be to control lifestyle factors. Dr. Jeffrey Dover, director of SkinCare Physicians, a dermatology practice in Chestnut Hill, Mass., says: "Some people have misrepresented the truth to suggest that there’s a lot you can do treat cellulite.”
Further Reading
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"Cellulite"
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