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New standard may minimize the risks and exaggerated benefits of medications

Published on April 28, 2004 at 4:05 AM · No Comments
Pharmaceutical ads marketed directly to the consumer may minimize the risks and exaggerate the benefits of medications, often confusing the public about what drugs are most effective, but Dartmouth Medical School (DMS) researchers have found a remedy. The solution, they say, lies in a “prescription drug benefits box,” a standardized table on every direct-to-consumer (DTC) ad that would present FDA approval data in clear, easy to understand terms.

Their study, appearing online in Health Affairs (http://www.healthaffairs.org), measured the public’s reaction to a benefit box that was inserted on three randomly selected DTC ads. The benefit box was modeled after the Food and Drug Administration’s (FDA) “Nutrition Facts Box” that appears on food packaging, such as cereal boxes. The box contained information obtained from the clinical trials of each drug that compared the various outcomes of patients who took the drug and those who took a placebo.

More than 200 people were interviewed after they viewed the new ads in an effort to gauge their level of understanding and whether they thought the ads would be helpful. The researchers found strong support for the benefit box, citing that “more than 90 percent [of respondents] preferred an ad which included the box to the standard version without it.”

“Requiring drug benefit data in DTC ads is an important step in educating the public about prescription drugs and promoting informed decision making,” said lead authors Drs. Lisa Schwartz and Steven Woloshin, associate professors of medicine and of community and family medicine at DMS.

One concern raised is that participants in the study “were very optimistic about the effectiveness of each study drug” and in each case, these perceptions dropped substantially after seeing the actual data from clinical trials in the benefit box. The study found that when shown a standard ad for one drug, 51 percent of consumers rated the drug as extremely or very effective. When the ad contained a drug benefit box, the rate dropped to just 26 percent.

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