When individuals with breast or prostate cancer followed a moderate, home-based exercise program using resistance bands and walking, the patients had less fatigue during radiation treatments, greater strength and could walk farther and faster in only four weeks, researchers discovered in a pilot study.
"At the end of the study, the patients in the exercise program were averaging more than 12,000 steps a day - which is above the American College of Sports Medicine and Centers for Disease Control recommendations of 10,000 steps a day for healthy people without cancer," said principal investigator Karen Mustian, Ph.D., of the University of Rochester James P. Wilmot Cancer Center.
"The results of this study are extremely promising and I am hopeful this that this type of research is creating a body of knowledge that is focused on treating the whole patient and all of the complexities of cancer," Mustian said.
Mustian presented the results of her randomized, controlled study at the American Society of Clinical Oncology (ASCO) 2006 annual meeting in Atlanta on June 5. ASCO awarded her an ASCO Junior Investigator Research Merit Award, given to outstanding early-career researchers to recognize their cancer prevention and control research.
Exercise is emerging as a new therapeutic weapon to help cancer patients manage and reduce side effects and improve quality of life. Studies are beginning to show that exercise is safe and feasible for many patients. In her clinical trial, Mustian found that the participants were enthusiastic and adhered well to the exercise program, even though they were older (average age was 60), half of them had received chemotherapy, and 84 percent had already endured a surgery. Still, 95 percent completed the prescribed exercise routine.
The National Cancer Institute funded the study. It included 38 people, 27 of whom were women diagnosed with breast cancer and 11 were men with prostate cancer. All of the patients were prescribed at least 30 radiation treatments, scheduled for five days a week during six weeks. Eligibility required patient consent and the completion of baseline tests to measure fatigue, strength and cardiovascular health before undergoing radiation.
Half of the group was randomly assigned to receive radiation therapy plus the home-based exercise prescription, and the other half received standard radiation therapy alone with no exercise.