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Screening all babies for high cholesterol could save many lives

Published on September 17, 2007 at 12:34 AM · No Comments

Doctors in the UK say in order to reduce the number of people suffering from heart disease children as young as 15 months should be screened for high cholesterol.

The doctors say a national screening programme involving a blood test for all babies, at the same time as routine vaccinations such as MMR are carried out, could help to slash the number of people in the UK with heart disease caused by hereditary high cholesterol.

According to the doctors about two in every 1,000 people are affected by familial hypercholesterolaemia, which carries a high risk of a build-up of cholesterol in the blood and premature death from heart disease.

Exactly who in the general population has the genetic disorder is difficult to ascertain.

David Wald, a consultant cardiologist and senior lecturer at the Wolfson institute of preventive medicine at the University of London, and colleagues carried out a study to find out the best way to screen for the disorder.

The team reviewed 13 studies involving a total of 1,907 people with hereditary high cholesterol and 16,221 without.

They found that screening was most effective in children aged between one and nine as it identified 88% of those with the genetic defect in that age group, but was much less successful in newborns and in young adults.

The idea is not to treat the child, but to identify the parent with a problem and put them on cholesterol-lowering drugs.

They say by identifying affected children an opportunity is provided to identify affected parents and the screening accomplishes two aims simultaneously: screening children and screening their parents.

They suggest treatment to lower cholesterol could be initiated immediately in the parent and delayed in the child until adulthood.

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