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Connection between expression of clock genes and sleep

Published on October 18, 2007 at 10:48 AM · No Comments

Genes responsible for our 24 hour body clock influence not only the timing of sleep, but also appear to be central to the actual restorative process of sleep, according to research published in the online open access journal BMC Neuroscience.

The study identified changes in the brain that lead to the increased desire and need for sleep during time spent awake.

"We still do not know why we benefit from sleep, or why we feel tired when we are 'lacking' sleep, but it seems likely that sleep serves some basic biological function for the brain such as energy restoration for brain cells or memory consolidation." Explains Dr Bruce O'Hara of the University of Kentucky, one of the neuroscientists who conducted the research. "We have found that clock gene expression in the brain is highly correlated to the build-up of sleep debt, while previous findings have linked these genes to energy metabolism. Together, this supports the idea that one function of sleep is related to energy metabolism."

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