Patients who have their wisdom teeth pulled and do not take antibiotics before surgery are twice as likely to get an infection after the surgery than those who take a single dose of antibiotics shortly before surgery, says Eastman Dental Center researchersYan-Fang Ren, DDS, PhD, MPH and Hans Malmstrom, DDS. The Eastman Dental Center is part of the University of Rochester Medical Center.
Their findings are published this month in the Journal of Oral & Maxillofacial Surgery.
Surgical extraction of impacted of wisdom teeth—or third molars—is the procedure carried out most commonly in oral surgery and general dental practices around the world,” said Ren. “Inflammation and infection associated with bacterial contamination are the most common complications after third molar surgery.” Because infection after surgery is usually accompanied by debilitating pain and functional impairment, clinicians have long sought effective ways to prevent complications after third molar surgery.
“Many clinical trials have been conducted in the past to investigate the controversial topic of using antibiotics before wisdom teeth surgery, but most of the published trials involved a sample size too small to support a conclusive outcome,” Ren explained. Through an extensive, meticulous process explained in the Journal, Ren and Malmstrom analyzed 20 published clinical trials involving nearly 3,000 patients.