Cryoablation, a procedure most commonly associated with destroying kidney and prostate tumors by freezing them, has been shown to offer durable pain relief of cancer that has spread to bone.
The procedure freezes and shrinks or destroys cancerous tumors in or near bone.
“Cancer patients are living longer and we need to be able to manage their pain over a long period of time,” says Matthew Callstrom, M.D., Ph.D., a radiologist at Mayo Clinic who will present his latest findings on cryoablation for pain management at the Radiological Society of North America (RSNA) annual meeting this week (Nov. 27).
Each year in the United States approximately 100,000 people develop cancer that spreads to the bone (metastasizes). This type of cancer causes extreme pain and often cannot be managed by narcotics or other standard treatments. New approaches in pain management are needed to help patients living longer with cancer, achieve a higher quality of life.
In this study, cryoablation was used to treat 34 patients whose primary cancers had spread to the bone. These patients either did not have success with conventional pain management treatments or refused such treatments. Eighty percent of the patients experienced a clinically significant reduction in pain. Furthermore, the treatment appears to have lasting effects: 24 weeks after undergoing the procedure, patients still reported significantly lower levels of pain.
“Two key parts of this study are that the reduction in pain lasts and their quality of life improves after receiving the treatment,” Dr. Callstrom says.
These results are important for two reasons: first, cryoablation worked after other treatments failed to provide adequate pain relief; second, cryoablation provides long-term pain relief. Radiation therapy, which is considered the gold standard in pain management for patients with focal pain associated with metastatic cancer, provides only short-term relief for many patients, he states.