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Addition of antibiotics to MS therapy could slow down progression of the disease

Published on December 11, 2007 at 1:30 PM · No Comments

Researchers from Louisiana State University in the U.S. are suggesting that the addition of antibiotics to standard drug therapy for multiple sclerosis, may slow down the progress of the disease.

The researchers believe the antibiotic possibly hinders the action of an enzyme that destroys certain cells in the nervous system.

Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease that affects the central nervous system.

It usually occurs in young adults and is more common in women than men and affects 2.5 million people worldwide.

MS usually affects genetically susceptible individuals but it's trigger remains unclear.

The inflammation affects parts of the brain causing a degeneration of brain tissue and in the most common type, relapsing-remitting MS, patients experience attacks of symptoms such as muscle weakness and spasms followed by periods of symptom-free remission.

Many patients with relapsing-remitting MS are often prescribed the medication interferon which boosts the immune system and fights viruses, but some still experience relapses and may continue to develop new areas of damaged brain tissue (lesions) which are visible on magnetic resonance imaging (MRI).

Dr. Alireza Minagar and colleagues conducted a small trial involving 15 patients with an average age of 44.5 years with relapsing-remitting MS who had been taking interferon for at least six months and were experiencing symptoms and developing new brain lesions.

The researchers suspect these unpredictable attacks may be triggered by an inappropriate response to viral or bacterial infections, with symptoms appearing and disappearing in a random manner.

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