Older adults with symptoms of depression appear more likely to gain abdominal fat, but not overall fat, over a five-year period, according to a report in the December issue of Archives of General Psychiatry.
About 10 percent to 15 percent of older adults have symptoms of depression, according to background information in the article. "Depression has been associated with the onset of diabetes, cardiovascular disease and cardiac mortality [death]," the authors write. "To better prevent occurrence of these major disabling and life-threatening diseases, more insight into underlying mechanisms relating depression to these disorders is needed."
Nicole Vogelzangs, M.Sc., of VU University Medical Center, Amsterdam, the Netherlands, and colleagues studied 2,088 adults age 70 to 79 years. Participants were screened for depression at the beginning of the study and their overall and abdominal obesity was recorded then and again after five years. Measures of overall obesity included body mass index and body fat percentage, while abdominal obesity was assessed using waist circumference, sagittal diameter (distance between the back and the highest point of the abdomen) and visceral fat (fat between the internal organs) measured by computed tomography.
At the beginning of the study, 4 percent of participants had depression. After adjusting for sociodemographic and other characteristics associated with weight changes, depression was associated with an increase in sagittal diameter and visceral fat over five years. "Such an association was not found for an increase in overall obesity and also appeared to be independent of changes in overall obesity, suggesting that depressive symptoms are rather specifically associated with fat gain in the visceral region," the authors write.