While many people are aware that drinking during pregnancy can lead to a range of Fetal Alcohol Spectrum Disorders (FASDs), including the serious Fetal Alcohol Syndrome (FAS), linkages between maternal-drinking measures and child outcomes have been inconsistent.
Researchers have now designed a "metric" or combination of measures that appear better able than individual measures to predict prenatal neurobehavioral dysfunction and deficits in children.
Results will be published in the April issue of Alcoholism: Clinical & Experimental Research and are currently available at Early View.
"The number of children being born with FAS remains unnecessarily high," said Lisa M. Chiodo, a researcher at Wayne State University and corresponding author for the study. "In part this is because it is difficult to identify patterns of drinking during pregnancy that put women's children at risk for FAS and other FASDs."
Chiodo said that although there are several measures of maternal drinking during pregnancy, their ability to predict child outcomes – particularly cognitive and behavioral problems – has been inconsistent. "We thought that combining many of the clinical and research measures of alcohol drinking into a single metric might help us find every child in our study who had been exposed to levels of alcohol that put them at risk," she said.
Only one other group has constructed a composite metric meant to identify women who were at risk of having a child with FASDs, Chiodo added, and the current metric differs from that one by focusing on problems related to alcohol drinking and not including other health concerns or risky behaviors.
The author of that other metric was Claire D. Coles, professor of psychiatry and behavioral sciences at the Emory University School of Medicine. "It is imperative that health-care professionals ask pregnant women about their alcohol and drug use in order to provide appropriate care for the women, and to provide anticipatory guidance for their children," she said. "Knowing that a woman has a substance-abuse problem or is an alcoholic is likely to be highly related to later developmental problems in the children."
Researchers examined a sample of 75 African-American mothers as well as their four- to five-year-old offspring. The mothers self-reported peri-conceptional and repeated in-pregnancy maternal drinking in response to a number of semi-structured interviews and standard screening instruments, which were then used to construct a metric of "maternal prenatal risk drinking." The offspring were tested for IQ, attention, memory, visual-motor integration, fine motor skills, and behavior. The metric was then assessed against these outcomes.
The metric identified more than 62 percent of the mothers as drinking at risk levels; 23 percent more than the individual selection criterion identified.