By now, most people have read stories about how to "grow your own organs" using stem cells is just a breakthrough away.
Despite the hype, this breakthrough has been elusive. A new report published in the March 2009 issue of The FASEB Journal (http://www.fasebj.org) brings bioengineered organs a step closer, as scientists from Stanford and New York University Langone Medical Center describe how they were able to use a "scaffolding" material extracted from the groin area of mice on which stem cells from blood, fat, and bone marrow grew. This advance clears two major hurdles to bioengineered replacement organs, namely a matrix on which stem cells can form a 3-dimensional organ and transplant rejection.
"The ability to provide stem cells with a scaffold to grow and differentiate into mature cells could revolutionize the field of organ transplantation," said Geoffrey Gurtner, M.D., Associate Professor of Surgery at Stanford University and a senior researcher involved in the work.