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How the retina works: Like a multi-layered jigsaw puzzle of receptive fields

Published on April 6, 2009 at 10:10 PM · No Comments

About 1.25 million neurons in the retina -- each of which views the world only through a small jagged window called a receptive field -- collectively form the seamless picture we rely on to navigate our environment.

Receptive fields fit together like pieces of a puzzle, preventing "blind spots" and excessive overlap that could blur our perception of the world, according to researchers at the Salk Institute for Biological Studies.

In the April 7 issue of the journal Public Library of Science, Biology, the scientists say their findings suggest that the nervous system operates with higher precision than previously appreciated and that apparent irregularities in individual cells may actually be coordinated and finely tuned to make the most of the world around us.

Previously, the observed irregularities of individual receptive fields suggested that the collective visual coverage might be uneven and irregular, potentially posing a problem for high-resolution vision. "The striking coordination we found when we examined a whole population indicated that neuronal circuits in the retina may sample the visual scene with high precision, perhaps in a manner that approaches the optimum for high-resolution vision," says senior author E.J. Chichilnisky, Ph.D., an associate professor in the Systems Neurobiology Laboratories.

All visual information reaching the brain is transmitted by retinal ganglion cells. Each of the 20 or so distinct ganglion cell types is thought to transmit a complete visual image to the brain, because the receptive fields of each type form a regular lattice covering visual space. However, within each regular lattice, the individual cells' receptive fields have irregular and inconsistent shapes, which could potentially result in patchy coverage of the visual field.

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