Blind for nine years, Sharron “Kay” Thornton has just regained her sight through a first-in-the-U.S. surgical procedure at Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine. The procedure -- modified osteo-odonto-keratoprosthesis (MOOKP) -- implanted her eyetooth in her eye, as a base to hold a prosthetic lens.
“I’m looking forward to seeing my seven youngest grandchildren for the first time,” said Thornton, 60, of Smithdale, Miss., who was blinded by Stevens-Johnson syndrome in 2000. The rare, serious skin condition destroys the cells on the surface of the eye causing severe scarring of the cornea. “We take sight for granted, not realizing that it can be lost at any moment,” she said. “This truly is a miracle.”
On Labor Day weekend, after the last in a series of surgeries by corneal specialist Victor L. Perez, M.D., associate professor of ophthalmology at Bascom Palmer Eye Institute, bandages were removed from Thornton’s eyes and she was able to recognize faces only hours after her surgery. Two weeks following her surgery, she is already reading newsprint with a visual acuity of 20/70 and it is expected to improve further as her surgical scars heal.
“Through the work of Dr. Perez’s team, patients in the United States now have access to this complex surgical technique, which has been available only in a limited number of centers in Europe and Asia,” said Dr. Eduardo C. Alfonso, M.D., chairman of Bascom Palmer Eye Institute (www.bascompalmer.com), the nation’s #1-ranked eye hospital.
Developed in Italy, MOOKP has proven effective as a solution to end-stage corneal disease where severe corneal scarring blocks vision and corneal transplants are no longer an option but the eye’s internal structures and optic nerve remain healthy. Patients may have suffered trauma to their cornea, the outside surface of the eye where a contact lens would sit, from chemical injuries, thermal burns, and inflammatory or autoimmune disorders, such as Stevens-Johnson syndrome.
“For certain patients whose bodies reject a transplanted or artificial cornea, this procedure ‘of last resort’ implants the patient’s tooth in the eye to anchor a prosthetic lens and restore vision,” explained Dr. Perez. “In Sharron’s case, we implanted her canine tooth, her eyetooth.”
Dr. Perez’s interdisciplinary team included Yoh Sawatari, D.D.S., assistant professor of clinical surgery at the Division of Oral and Maxillofacial Surgery and Dentistry at the University of Miami/Jackson Memorial Medical Center, who extracted the patient’s canine or “eyetooth” and surrounding bone. In MOOKP, the tooth and surrounding bone are shaved and sculpted, and a hole is drilled for the insertion of an optical cylinder lens. Next, to bond the tooth and lens as a bio-integrated unit, they are implanted under the patient’s skin in the cheek or shoulder. Meanwhile, the ophthalmologist prepares the surface of the eye for implantation of the prosthesis by removing scar tissue surrounding the damaged cornea.