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UAB's researchers find early indicators for Alzheimer's disease

Published on September 22, 2009 at 5:21 AM · No Comments

Inability to handle financial transactions or manage money may be an early indicator that a person with mild memory problems soon is likely to develop Alzheimer's disease, according to new research from the University of Alabama at Birmingham (UAB) Alzheimer's Disease Center, part of the Department of Neurology.

The findings, published in the Sept. 22 edition of Neurology, the medical journal of the American Academy of Neurology, examined patients with a condition known as mild cognitive impairment (MCI), thought to be a precursor to Alzheimer's.

The researchers followed 87 people with MCI and 76 controls with no memory problems. The participant's ability to manage certain financial skills was assessed at the beginning of the study and then again one year later, using a UAB-developed tool called the Financial Capacity Instrument (FCI). The skills included understanding a bank statement, balancing a checkbook, paying bills, preparing bills for mailing and counting coins and currency.

During the course of the year, 25 of the MCI patients had progressed to Alzheimer's disease. The overall FCI scores for those 25 participants decreased 6 percent from their original scores and 9 percent for checkbook-management skills. The control group and those MCI patients who did not progress to dementia maintained the level of their FCI scores throughout the year.

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