A recently released paper published in the journal Alternatives to Laboratory Animals (ATLA 37, 399-416), presents a serious challenge to long-standing claims that animals are an important part of human cancer research. "An Examination of Chimpanzee Use in Human Cancer Research" found that chimpanzees, our closest genetic relatives, have contributed little to combating cancers and cost society not only time but wasted research dollars. The paper comes on the heels of a national ad campaign (ResearchSaves, Sept.16, 2009) launched by the Foundation for Biomedical Research advocating animal use.
Geneticist Jarrod Bailey, Ph.D., Science Director for Project R&R: Release and Restitution for Chimpanzees in U.S. Laboratories conducted a comprehensive analysis of the use of chimpanzees in cancer research over the past four decades as well as proposed future uses.
According to Bailey, "There are significant biological differences between humans and chimpanzees. Despite an overall - although superficial - genetic similarity to humans, and despite claims by the research industry, chimpanzees have proven to be a poor model for human cancer research."
The study found that chimpanzee tumors are extremely rare and biologically different from human cancers. Literature describing potential new cancer therapies tested in chimpanzees included significant caveats concerning species differences, and described interventions that had not been pursued in humans, presumably due to adverse reactions. Further, available evidence indicates that chimpanzees are not essential in the development of monoclonal antibody therapies for cancer treatment.