Medtronic, Inc. (NYSE: MDT) today announced study results from an oral presentation at the International Diabetes Federation’s World Diabetes Congress held in Montreal, Canada. This scientific convention highlights the latest developments in clinical research aimed at improving diabetes management and outcomes.
Improved Glycemic Control and Evidence for Beta Cell Preservation
In an oral presentation entitled, “The ONSET trial of sensor-enhanced CSII in children with new onset type 1 diabetes,” results of a prospective, randomized, multi-center trial were shared. The physician-initiated study, performed in five pediatric centers, assessed whether children (ages 1-16) newly diagnosed with type 1 diabetes could achieve improved glycemic control using an insulin pump augmented with Personal continuous glucose monitoring (CGM), known as the MiniMed Paradigm® REAL-Time System, compared to a control group using a conventional insulin pump with self monitoring of blood glucose (SMBG).
“It is quite evident that children with type 1 diabetes can benefit from using insulin pump therapy with real-time continuous glucose monitoring at the onset of their disease,” said Thomas Danne, M.D., lead investigator and chief physician at the “Auf der Bult” Diabetes Center for Children and Adolescents in Hanover, Germany. “In fact, we noted evidence that reducing glycemic variability has an effect on the pancreas, preserving beta cell function, which likely will improve diabetes outcomes over the long-term in these children.”
A total of 160 patients in this Medtronic-supported study were randomized to use conventional insulin pump therapy with SMBG or an insulin pump with Personal CGM for 12 months. Key results highlighted during the oral presentation include: