Children exposed prenatally to tobacco smoke and during childhood to lead face a particularly high risk for ADHD, according to research done at Cincinnati Children's Hospital Medical Center.
The study estimates that up to 35 percent of ADHD cases in children between the ages of 8 and 15 could be reduced by eliminating both of these environmental exposures. This could translate into up to 800,000 children
"Tobacco and lead exposure each have their own important adverse effect," says Tanya Froehlich, M.D., a physician in the Division of Developmental and Behavioral Pediatrics at Cincinnati Children's and the study's lead author. "But if children are exposed to both lead and prenatal tobacco, the combined effect is synergistic."
The study is to be published online Nov. 23 by Pediatrics.
"Although we tend to focus on ADHD treatment rather than prevention, our study suggests that reducing exposures to environmental toxicants might be an important way to lower rates of ADHD," says Robert Kahn, MD, MPH., a physician and researcher at Cincinnati Children's and the study's senior author.
The researchers found that children exposed prenatally to tobacco smoke were 2.4 times more likely to have ADHD. Those with blood lead levels in the top third had a 2.3 fold increased likelihood of ADHD, despite levels well below the Centers for Disease Control action level of 10 micrograms per deciliter. Dr. Froehlich and her colleagues found the risk of ADHD more than eight times higher for children exposed to both tobacco and lead compared to unexposed children.