Gene Security Network, Inc (GSN) today announced that Human
Reproduction published results validating the exceptional
performance of GSN’s proprietary Parental SupportTM
technology over existing methods to detect chromosome abnormalities
during in vitro-fertilization (IVF). Human Reproduction is the
flagship journal of the European Society for Human Reproduction and
Embryology (ESHRE). The study was conducted in partnership with leading
IVF clinics in the United States.
“Preclinical validation of a microarray method for
full molecular karyotyping of blastomeres in a 24-h protocol”
This study marks the first time that technology used for Preimplantation
Genetic Screening (PGS) has been compared head-to-head with the leading
test for chromosome analysis outside of the PGS setting, metaphase
karyotyping. GSN’s accuracy was shown to be roughly equivalent to
metaphase karyotyping, in addition to being superior to existing PGS
technologies (98.7% overall accuracy versus published reports of 85-90%
accuracy for testing performed using Fluorescent In-Situ hybridization
[FISH]). GSN began offering its 24 Chromosome Aneuploidy Screening with
Parental Support test to IVF clinics in October 2008 and over
sixty IVF clinics are now offering the test in the United States and
Europe.