Pro-Pharmaceuticals reports net loss applicable to common stock of $1.3M for fourth-quarter 2009

Pro-Pharmaceuticals, Inc. (OTC: PRWP.OB), a developer of therapeutics that target Galectin receptors to treat cancer and fibrosis, today reported its financial results for full year and fourth quarter, ended December 31, 2009. These results are included in the Company’s Annual Report on Form 10-K which has been filed with the SEC.

“Pro-Pharmaceuticals continues to make progress toward its goal to commercialize DAVANAT®”

“Pro-Pharmaceuticals continues to make progress toward its goal to commercialize DAVANAT^®,” said Theodore Zucconi, Ph.D., Chief Executive Officer, Pro-Pharmaceuticals. “We plan to initiate a Phase III clinical trial for late stage colorectal cancer patients as soon as we raise sufficient funds. In addition, the Company is actively engaged in discussions with potential partners to distribute DAVANAT^® internationally.”

For the fourth quarter of 2009, the Company reported a net loss applicable to common stock of $1.3 million, or ($0.03) per share, basic and diluted, compared with a net loss of $0.9 million or ($0.02) per share for the same period in 2008. For the full year 2009, the Company reported a net loss applicable to common stock of $9.4 million, or ($0.20) per share, basic and diluted, with non-cash expenses of approximately $5.1 million, compared with a net loss of $3.4 million, or $(0.07) per share in 2008. The full year 2009 results included $1.4 million of non-cash expense related to the change in the fair value of warrants compared with $2.1 million of non-cash income in 2008. The full year 2009 results include a $2.0 million non-cash expense related to dividends and accretion on the preferred stock compared with $0.2 million in 2008.

Research and development expense for the fourth quarter of 2009 was $0.2 million, compared with $0.3 million for the same period in 2008. The decrease was due primarily to overall lower activity in clinical and pre-clinical programs as a result of cost containment measures. Research and development expense for the full year 2009, was $1.1 million, compared with $1.8 million in 2008. The decrease was due primarily to overall lower activity as a result of cost containment measures and decreased salaries and stock-based compensation. Also, during the full year 2008, the Company incurred costs related to the filing of the DAVANAT^® Drug Master File with the FDA which were not incurred during 2009.

General and administrative expense for the fourth quarter of 2009 was $0.9 million, compared with $0.8 million for the same period in 2008. General and administrative expense for the full year 2009 was $5.0 million as compared to $3.6 million for 2008. The increase is due primarily to increased business development efforts, increased stock-based compensation, and the recognition of severance obligations related to the departure of our former Chief Executive Officer.

Annual Shareholders Meeting

The Company’s Annual Meeting of Shareholders is scheduled to be held on May 25th at the Company’s office in Newton, Massachusetts.