ADHD drugs don’t raise risk for heart attacks or stroke: Study

Published on November 2, 2011 at 8:00 PM · 1 Comment

By Dr Ananya Mandal, MD

Drugs known as stimulants, that are used to treat attention deficit hyperactivity disorder do not increase the risk of heart attacks, strokes or sudden death, U.S. researchers said on Monday. This study finding should reassure millions of parents whose children take the drugs.

For the study, Cooper's team used prescription data from four large, geographically and demographically diverse health plans on 1,200,438 children and youth (aged between 2 and 24), including both current and past users of the drugs Ritalin or Adderall. They checked health records for evidence of heart problems, including heart attacks, strokes and sudden cardiac deaths, in children who were currently taking the drugs or who had taken them.

The team found no increased risk of heart problems for either current or past users of the drugs. Yet because there were so few cases of serious heart problems - just 81 - the study may not have been large enough to detect it.

“We don't see any evidence of increased risk,” said Dr. William Cooper of Vanderbilt University, whose study was published in the New England Journal of Medicine.

This study is one of the three commissioned by the Food and Drug Administration to understand the potential heart risks of the drugs after U.S. and Canadian regulators received a number of reports in 2006 of heart attacks, strokes and sudden cardiac arrest in children taking the medications.

The reports prompted several FDA advisory committee hearings on heart problems, and Health Canada temporarily suspended marketing of ADHD drugs. The concerns also prompted the American Heart Association to issue guidelines suggesting that children who were just starting to take the drugs should be tested for potential underlying heart problems.

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  1. E.M. Wollof E.M. Wollof United States says:

    These studies cover up the true harm that can come from giving these medications to children. There are many times that death doesn't happen physically, but is very real mentally. I found this video that illustrates the point rather well:

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