Close to half of adverse reactions to medicines among adult hospital and emergency patients could be avoided, shows a study from the Nordic School of Public Health NHV.
"This highlights the need for further efforts in healthcare to avoid unnecessary harm from medicines", says researcher Katja M Hakkarainen.
The research group at Nordic School of Public Health NHV, Sweden, investigated preventable adverse drug reactions, i.e. side effects of medicines, in different patient groups. They found that 52% of adverse drug reactions experienced by outpatients getting hospitalised or visiting emergency care could have been prevented. In this outpatient group, 2% of all patients suffered from preventable adverse drug reactions. According to the study, 45% of adverse drug reactions experienced by inpatients during hospitalisation could have been avoided, but the percentage of inpatients with preventable adverse drug reactions could not be estimated precisely.
Pharmacist Katja M Hakkarainen and colleagues made these findings when they summarised the results of 22 research articles published in 1994-2010, from Asia, Australia, Europe, and North America. The studies included 48 797 outpatients getting hospitalised or visiting emergency care, and 24 128 inpatients in hospitals. In the summarised studies, an adverse drug reaction was considered preventable when the medication therapy was not in accordance with practice standards, for example dosing or monitoring was inappropriate.