Jun 8 2012
The transplantation unit at Jackson Memorial Hospital and the University
of Miami, FL, USA has entered into a research project with the Allenex
group company AbSorber. The project is a pilot study evaluating the
endothelial cell cross match XM-ONE® in their Living Donor program.
University of Miami will investigate if antibodies detected by XM-ONE®
will affect the outcome for the individual patient, in pre- and
post-transplant situations.
Corrected name: Dr Giselle Guerra. This news item sent first time June 7.
"Non-HLA antibodies, especially endothelial cell antibodies, play a
significant role as risk markers of acute rejection in kidney transplant
recipients" says Dr. Giselle Guerra, MD at the University of Miami and
principal investigator of the study. "However, the post-transplant risk
evaluation of these antibodies have not been studied and we are excited
to have this possibility", she continues.
This prospective pilot study will include 138 patients and is estimated
to have an enrollment period of two years. Patients will thereafter be
monitored for six months post transplantation.
"The last years a number of researchers have published important data on
the relevance of non-HLA antibodies as well as XM-ONE® used for risk
assessment in a pre-transplant setting. An obvious next step is to
investigate the presence and importance of non-HLA antibodies
post-transplantation using XM-ONE®. We are proud that Dr. Guerra and her
co-workers at Jackson Memorial Hospital approached us to perform this
important study", says Anders Karlsson, CEO of Allenex..
Source: Allenex