T2 Biosystems, a company developing direct detection products enabling superior diagnostics, today announced the presentation of data on endotoxin detection at the American Society for Microbiology General Meeting, June 16-19, 2012, in San Francisco, CA. The T2Endotoxin assay is a novel method to screen injectable drugs and medical devices for the presence of endotoxins that are produced by gram negative bacteria or fungi, combining the standard Limulus Amoebocyte Lysate (LAL) reagent with Company's T2MR technology. LAL forms a gel in response to the presence of endotoxin and changes in LAL are directly measured by T2MR, similar to the T2Hemostasis application for coagulation and platelet disorders. The data presented at ASM demonstrate that the T2Endotoxin assay provided higher sensitivity, faster detection and lower reagent consumption when compared with commercially available assays.
“The T2Endotoxin assay extends the reach of T2MR detection to the screening of injectable drugs and medical devices for the presence of endotoxin, which is produced by gram negative bacteria and fungi, a field where the current methods rely on decades-old technology”
"The T2Endotoxin assay extends the reach of T2MR detection to the screening of injectable drugs and medical devices for the presence of endotoxin, which is produced by gram negative bacteria and fungi, a field where the current methods rely on decades-old technology," said John McDonough, CEO, T2 Biosystems. "T2Endotoxin enables rapid and ultrasensitive detection of endotoxin, with reduced reagent consumption, delivering many of the same advantages that T2 Biosystems brings to molecular and hemostasis assays. The addition of T2Endotoxin to the range of applications enabled by T2MR demonstrates the versatility of our platform and its ability to solve diverse analytic problems."