Actinium Pharmaceuticals, Inc. a biotechnology company focused on developing innovative, alpha particle radiotherapy targeted cancer treatments addressing major unmet medical needs, today announced that it has successfully treated the first cohort of patients in a Phase I/II study of Actimab-A™ in Acute Myeloid Leukemia (AML) clinical trial. Patients were treated at Memorial Sloan Kettering Cancer Center in New York City.
Patients enrolled in the first cohort in this ongoing trial were treated at a dose level of 0.5 microCi/kg of Actimab-A™, with two consecutive doses given a week apart. Actimab-A™ treatment consists of the isotope Actinium 225 attached to the anti-CD33 monoclonal antibody lintuzumab (HuM195).
"As we continue to achieve our stated milestones, completion of the first cohort brought us another step closer to the Phase II portion of the trial," said Dr. Dragan Cicic, the CEO of Actinium Pharmaceuticals. "We are looking forward to accelerated accrual and timely completion of the current trial and moving into Phase II as planned."