UK scientists make breakthrough in new method of brain tumour diagnosis

Published on September 20, 2012 at 7:40 AM · No Comments

UK scientists have made a breakthrough in a new method of brain tumour diagnosis, offering hope to tens of thousands of people.

Researchers, led by Professor Francis Martin of Lancaster University, have shown that infrared and Raman spectroscopy - coupled with statistical analysis - can be used to tell the difference between normal brain tissue and the different tumour types that may arise in this tissue, based on its individual biochemical-cell 'fingerprint'.

Spectroscopy is a technique that allows us to analyse light by breaking it into its component parts and studying the resulting pattern or spectrum.

Currently, when surgeons are operating to remove a brain tumour it can be difficult to spot where the tumour ends and normal tissue begins.

But new research published online in Analytical Methods this month has shown it is possible to spot the difference between diseased and normal tissue using Raman spectroscopy - a type of spectroscopy which works effectively on living tissue, giving accurate results in seconds.

This is a key development which means it is now theoretically possible to test living tissue during surgery, helping doctors to remove the complete tumour whilst preserving intact adjacent healthy tissue.

The fingerprinting technique was also able to identify whether the tumours arose in the brain or whether they were secondary cancers arising from an unknown primary site. This is a key development which could help reveal previously undetected cancer elsewhere in the body, improving patient outcomes.

Professor Francis Martin said: "These are really exciting developments which could lead to significant improvements for individual patients diagnosed with brain tumours.

We and other research teams are now working towards a sensor which can be used during brain surgery to give surgeons precise information about the tumour and tissue type that they are operating on."

The information obtained by this method can be combined with conventional methods, for example immunohistochemistry, to diagnose and grade brain tumours to allow for more accurate planning and execution of surgery and/or radiation therapy.

This offers more potential for individualised treatment and better long-term survival.

Posted in: Device / Technology News | Medical Science News | Medical Condition News

Tags: , , , ,

Read in | English | Español | Français | Deutsch | Português | Italiano | 日本語 | 한국어 | 简体中文 | 繁體中文 | Nederlands | Русский | Svenska | Polski
Comments
The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News-Medical.Net.
Post a new comment
Post
You might also like... ×
Research sheds new light on brain's complicated barrier tissue