Trovagene, Inc. (NASDAQ: TROV), a developer of transrenal molecular diagnostics, announced it has granted Duke University and Duke University Health Systems a non-exclusive license to incorporate nucleophosmin protein (NPM1) into research and clinical testing services for acute myelogenous leukemia (AML). Trovagene holds an exclusive worldwide license to U.S. patent 8,222,370 and the corresponding group of U.S. and foreign patent applications around NPM1. Terms of the agreement include upfront fees and royalty payments. Additional financial terms were not disclosed.
"Trovagene is pleased to add Duke University Health System to its list of worldwide licensees of the NPM1 marker," said Antonius Schuh, Ph.D., chief executive officer for Trovagene. "Use of NPM1 is part of the NCCN guidelines for the treatment of AML. Clinical and academic laboratories are increasingly interested in licensing this assay so they can offer it directly to their physicians for use in patient care."