In addition to its lipid-lowering effect, statins exert anti-inflammatory and antioxidant effects as well. Statins also provide protection against renal, pulmonary and myocardial ischemia/reperfusion injury. However, little evidence is available on similar changes in cerebral ischemia/reperfusion injury.
Therefore, Dr. Qiuyun Tu and colleagues from Third Xiangya Hospital of Central South University in China verified that atorvastatin, a commonly used lipid-lowering drug, protects against cerebral ischemia/reperfusion injury through anti-infammatory and antioxidant effects. The relevant study has been published in the Neural Regeneration Research (Vol. 9, No. 3, 2014).