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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Study demonstrates therapeutic potential of new class of synthetic oligonucleotides for DMD treatment

Research efforts associating scientists from the CNRS, UVSQ and INSERM within the Laboratoire END-ICAP, working in collaboration with a team from the University of Bern, has demonstrated the therapeutic potential of a new class of synthetic oligonucleotides in the treatment of Duchenne muscular dystrophy (DMD) using RNA "surgery".

4 Feb 2015

Researchers suggest novel concept for developing vaccines against HIV and cancer

A experimental trial has shown successful by inducing serum in mice and has been highly neutralizing towards those ailments.

4 Feb 2015

Asthmatic patients suffering from xerostomia have a poorer level of control disease

Scientists at the University of Granada and the High Resolution Hospital in Loja (Granada) prove that asthmatic patients who suffer from xerostomia (dry mouth syndrome) have a poorer level of control disease. Whether an asthmatic patient also suffers from severe xerostomia can be of great use for the pneumologist when it comes to establishing that particular patient's level of control disease.

4 Feb 2015

Researchers use pulsed light to modify lactose protein that causes 10% of milk-related allergies

The researchers have managed to modify a type of lactose protein called β-lactoglobulin artificially by means of a treatment with pulsed light. This protein, which is present in lactose serum, is responsible for approximately 10% of milk-related allergies. As a result of this treatment, milk becomes much more digestible.

4 Feb 2015

Amgen's biosimilar Phase 3 rheumatoid arthritis study meets primary and secondary endpoints

Amgen today announced a Phase 3 study evaluating the efficacy and safety of biosimilar candidate ABP 501 compared with Humira® (adalimumab) in patients with moderate-to-severe rheumatoid arthritis met its primary and key secondary endpoints.

4 Feb 2015

Two genetic mutations can interact to reduce risk for heart attack

Researchers have determined that two mutations on a single gene can interact in a way that lowers the carrier's risk for a heart attack.

4 Feb 2015

Study opens door for development of tools to modulate CoQ10 synthesis in human cells

A study which counts with the participation of University of Granada scientists has provided new data on the Q10 coenzyme (CoQ10), a molecule which is synthesized within the cells of the organism itself and which has essential functions for cellular metabolism.

4 Feb 2015

MGH, MIT researchers reveal how the brain controls different sleep states

Researchers at Massachusetts General Hospital and Massachusetts Institute of Technology have added another piece to the complex puzzle of how the brain controls one of the most essential functions - sleep.

4 Feb 2015

Study may offer insight into pathology of autism, Alzheimer's disease

For parents of children struggling with autism, the dearth of information is heartbreaking. Medical professionals are hard put to answer the primary questions: Who is autistic? What causes autism? What treatments are available? The situation is similar for Alzheimer's patients and relatives, who are helpless before the aggressive disease devouring a sufferer's identity.

4 Feb 2015

Research opens door to development of new therapies to block HIV-associated neurocognitive disorders

While antiretroviral therapies have significantly improved and extended the lives of many HIV patients, another insidious and little discussed threat looms for aging sufferers - HIV-associated neurocognitive disorders (HAND). The disorders, which strike more often in HIV patients over age 50, can result in cognitive impairment, mild to severe, making everyday tasks a challenge.

3 Feb 2015

Researchers successfully monitor expression of genes in neurons

Gene expression within neurons is critical for the formation of memories, but it's difficult to identify genes whose expression is altered by learning. Now researchers have successfully monitored the expression of genes in neurons after rats were exposed to auditory fear conditioning, in which a neutral auditory tone is paired with electric shock.

3 Feb 2015

ISP shows promise in stopping fatal arrhythmias after heart attack

Case Western Reserve's chemical compound aimed at restoring spinal cord function may have an additional purpose: stopping potentially fatal arrhythmias after heart attack.

3 Feb 2015

New study helps explain how booster shots trigger immune 'memory' to improve

The last time you were in the doctor's office for a vaccine booster shot, did you wonder why you needed one? Exactly how booster shots offer long-term protection from viruses has long been a mystery to scientists.

3 Feb 2015

Bern researchers develop active substance for treating Duchenne muscular dystrophy

Duchenne muscular dystrophy is a congenital disease which causes muscle degeneration and eventual death in teenagers. Recently, researchers from Bern developed an active substance, which they together with an international team tested successfully.

3 Feb 2015

Isis announces top-line results from ISIS-PTP1B Rx Phase 2 study in type 2 diabetes patients

Isis Pharmaceuticals, Inc. announced today top-line results from a Phase 2 study of ISIS-PTP1B Rx in patients with type 2 diabetes. In the Phase 2 study patients treated with ISIS-PTP1B Rx achieved statistically significant reductions in body weight and hemoglobin A1c (HbA1c).

3 Feb 2015

Research describes new way of shrinking ovarian cancer tumors, improving drug delivery

New research published in the February 2015 issue of The FASEB Journal, may eventually help improve the five-year survival rate of ovarian cancer patients by describing a new way of shrinking ovarian cancer tumors while also simultaneously improving drug delivery.

3 Feb 2015

Using NMR to study influenza and TB: an interview with Dr. Tim Cross

In this interview, Tim Cross, Director of the NMR and MRI programs at the National High Magnetic Field Lab (NHMFL) in Tallahassee, Florida, talks about his research into protein structures in viruses and bacteria, and how the findings will affect medical research into disease prevention.

From Bruker BioSpin - NMR, EPR and Imaging 3 Feb 2015

Vanderbilt researchers discover new reset button for the brain's master biological clock

The discovery of a new reset button for the brain's master biological clock could eventually lead to new treatments for conditions like seasonal affective disorder, reduce the adverse health effects of working the night shift and possibly even cure jet lag.

3 Feb 2015

Dartmouth scientists discover novel cancer resistance mechanism

In the search for new approaches to treat ERBB2 (also known as HER2) positive breast cancers that have become drug-resistant, Dartmouth's Norris Cotton Cancer Center investigator Manabu Kurokawa, PhD, led a team in discovery of a novel cancer resistance mechanism with findings published in Cell Cycle.

3 Feb 2015

International researchers discover gene that causes familial scoliosis

The discovery of the first gene causing familial scoliosis was announced by an international France-Canada research team today. "Mystery surrounds the cause of scoliosis, which is a three dimensional deformation of the vertebral column. Many researchers have been attempting to uncover the origins of this disease, particularly from a genetic point of view," explained leading co-author Dr Florina Moldovan of the University of Montreal and the CHU Sainte Justine research hospital.

3 Feb 2015

Protein News and Research

Further Reading

Study demonstrates therapeutic potential of new class of synthetic oligonucleotides for DMD treatment

Researchers suggest novel concept for developing vaccines against HIV and cancer

Asthmatic patients suffering from xerostomia have a poorer level of control disease

Researchers use pulsed light to modify lactose protein that causes 10% of milk-related allergies

Amgen's biosimilar Phase 3 rheumatoid arthritis study meets primary and secondary endpoints

Two genetic mutations can interact to reduce risk for heart attack

Study opens door for development of tools to modulate CoQ10 synthesis in human cells

MGH, MIT researchers reveal how the brain controls different sleep states

Study may offer insight into pathology of autism, Alzheimer's disease

Research opens door to development of new therapies to block HIV-associated neurocognitive disorders

Researchers successfully monitor expression of genes in neurons

ISP shows promise in stopping fatal arrhythmias after heart attack

New study helps explain how booster shots trigger immune 'memory' to improve

Bern researchers develop active substance for treating Duchenne muscular dystrophy

Isis announces top-line results from ISIS-PTP1B Rx Phase 2 study in type 2 diabetes patients

Research describes new way of shrinking ovarian cancer tumors, improving drug delivery

Using NMR to study influenza and TB: an interview with Dr. Tim Cross

Vanderbilt researchers discover new reset button for the brain's master biological clock

Dartmouth scientists discover novel cancer resistance mechanism

International researchers discover gene that causes familial scoliosis

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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