Women who get less than the recommended eight hours sleep a night are at higher risk of heart disease and heart-related problems than men with the same sleeping patterns.
Research by the University of Warwick and University College London has found that levels of inflammatory markers vary significantly with sleep duration in women, but not men.
The study, published today (Weds) in the American journal SLEEP, found levels of Interleukin-6 (IL-6), a marker related to coronary heart disease, were significantly lower in women who reported sleeping eight hours as compared with 7hours.
A second marker, High-sensitivity C-reactive protein (hs-CRP), is predictive of future cardiovascular morbidity. Levels of hs-CRP were significantly higher in women who reported sleeping five hours or less.
Lead author of the study, Associate Professor of Biochemical Medicine at Warwick Medical School Michelle Miller said short-term sleep deprivation studies have shown that inflammatory markers are elevated in sleep-deprived individuals, suggesting that inflammatory mechanisms may play a role in the cardiovascular risk associated with sleep deprivation.
She said: "Our study may provide some insight into a potential mechanism for the observation in previous studies which indicates an increased risk of death from cardiovascular disease in individuals who have less than five hours sleep per night and increased risk of non-cardiovascular death in long sleepers."
This is the first large-scale study to describe the associations between measures of inflammation and sleep duration in both men and women.