Using small molecules (purine analogs) scientists managed to reverse multidrug resistance in lung cancer, a common obstacle to successful cancer chemotherapy.
HTDS www.htdsmedical.com (HTDS) - The issuer's Serbia based operating subsidiary Slavica BioChem www.slavicabiochem.com brings attention to its Mindup Bioresearch cancer project working on molecular origins of lung cancer: prospects for personalized prevention and therapy. On October 8 2009, the company posted a filing on Pink Sheets titled MindUp Cancer Project.
The company is using this opportunity to shed some light the significance of that filing. The MindUp group focused their investigation on inactivation of tumour suppressors as molecular marker events highly related to the pathogenesis of non-small cell lung carcinoma (NSCLC). To that end, they use paired tumour and normal lung tissue samples and blood obtained from patients with NSCLC after surgery. These results are presented at AACR (American Association for Cancer Research) Conference, Frontiers in Basic Cancer Research, http://www.aacr.org/home/scientists/meetings--workshops/frontiers-in-cancer-prevention-research.aspx October 8 - 11, 2009. Boston, Massachusetts, on poster entitled "The impact of inactivation of p53 and PTEN tumor suppressors on promotion and progression of human non-small cell lung carcinoma" (authors: Tijana Andjelkovic, Jasna Bankovic, Vedrana Milinkovic, Ana Podolski, Sabera Ru dijic, Nikola Tanic).