Ohr Pharmaceutical Inc. (OTCBB: OHRP) is developing OHR/AVR118 for treatment of cachexia based on technology acquired earlier this year from Advanced Viral Research Corp. OHR/AVR118 has shown excellent therapeutic efficacy and safety in human clinical trials in over 100 patients with applications for cachexia in Cancer and AIDS patients, as well as Rheumatoid Arthritis. OHR/AVR118 is a unique immunomodulator that affects the synthesis of chemokines and cytokines. Its main action is anti-inflammatory through the inhibition and modulation of cellular pro-inflammatory chemokine and cytokine synthesis, especially tumor necrosis factor-alpha (TNF-alpha). Moreover, the drug acts to maintain immune homeostasis. It prevents the very destructive and toxic cytokine showers that result from certain viral infections such as influenza and many cancers, including the chemotherapeutic drugs and radiotherapy given to shrink tumors. As would be expected based on its molecular immunomodulating properties and mechanism of action, Ohr118 has also shown efficacy in the treatment of the important auto-immune disease Rheumatoid Arthritis.