Researchers at Children's Hospital Boston Aim to Demystify Science and Share Potential for Treatments and Cures on Range of Diseases from Diabetes to Parkinson's
Exactly one year to the day after President Obama's historic decision to reverse an eight-year restriction on federally funded embryonic stem cell research, the Children's Hospital Boston Stem Cell Program today announced the development of a unique, comprehensive web site and released a candid video message from its top researchers on the current state of stem cell research to introduce the new site: stemcell.childrenshospital.org.
Designed as an engaging and accessible resource, the new site seeks to demystify the science, clear up misperceptions and illuminate the public about the power and value of different types of stem cells to create cost effective treatments and potential cures for a range of diseases -- including Type I diabetes, Parkinson's, leukemia and other blood cancers, Huntington's, sickle cell anemia, neurological disorders, and more.
Beginning today, visitors to stemcell.childrenshospital.org can access an introductory video, featuring Drs. Leonard Zon and George Daley, along with Stem Cell Task Force leader President of the Kraft group and the New England Patriots, Jonathan Kraft -- who together cite the promise and ongoing challenges in this field and call for new support. Visitors can also sign up to receive updates leading up to the official launch of the website -- which will be fully operational on April 26, 2010.
The timing of the April 26th date is also significant in the field of stem cell research, because it marks the 5th anniversary of the release of guidelines from the US National Academy of Sciences (NAS) for the responsible conduct of embryonic stem cell research. Children's was among the first to adopt those guidelines, and in the five years since the guidelines were released, the Stem Cell Program at Children's Hospital has emerged as an internationally recognized leader in stem cell research.
Despite operating under significant constraints over the past eight years, Children's made remarkable progress on multiple fronts:
* Children's created an aggressive business plan, their roadmap for bringing research from the bench to the bedside.
* Children's produced 11 of the first 13 hESC lines approved by the US National Institutes of Health (NIH) for federal funding in December, 2009. Children's is receiving requests for these lines from scientists across the U.S. who are studying diseases from diabetes to Parkinson's.
* Drs. Daley and Zon have been awarded major grants from the NIH for the creation of human models of disease and to study whether stem cells reprogrammed from adult stem cells (iPS) cells are equivalent to those derived from human embryos, one of the field's most pressing questions.
* Dr. Zon's research has already been rapidly translated from the laboratory to the clinic: studies on blood formation in the zebrafish -- a model organism pioneered by the Zon lab -- led to the discovery of a drug that expands blood stem cells, which is now being tested in patients undergoing umbilical cord blood transplants.
* Children's Researchers were the first to isolate lung stem cells, with implications for treating lung cancer, cystic fibrosis and pulmonary diseases.
* Science Magazine cited Dr. Daley's creation of disease-specific stem cells from patients in its 2008 "Breakthrough of the Year" issue.
"Stem cell research is an incredibly exciting field and this is an extraordinary time to be part of it," said Leonard Zon, MD, Director of Children's Hospital's Stem Cell Program. "In just the five short years since the release of the NAS guidelines, we have seen major breakthroughs in the science and in the techniques we can use to investigate potential therapies for a wide range of diseases. It's absolutely essential that we continue that forward momentum."
The Human Face of Stem Cell Research