Researchers at Wayne State University's Department of Nutrition and Food Science believe they've uncovered a unique method to control and regulate cholesterol using biologically active molecules isolated from ProAlgaZyme™ ("PAZ") -- a proprietary algal infusion produced by Health Enhancement Products, Inc., of Scottsdale, Arizona (OTCBB:HEPI).
The company has filed a new patent application to describe the method or methods of cholesterol regulation, which are considered novel and scientifically significant. Dr. Smiti Gupta, associate professor at Wayne State University and the principal investigator leading the research team, will be providing additional information in the near future. The scientific team is planning a press conference to announce details of the discoveries once the intellectual property has been fully protected.
Results of this most recent study indicate that these biologically active molecules regulate cholesterol metabolism by stimulating genetic signals that help spur the creation of HDL and simultaneously slow down the degradation of existing HDL particles back to the LDL form of cholesterol.
The isolated molecules have been shown to significantly raise HDL, the 'good' cholesterol, from 105.27 to 138.69 mg/dl (approx. 32%), and lower LDL, the 'bad' cholesterol from 131.00 to 79.57 mg/dl (approx. 39%), in a previous Wayne State study using hamsters on a high-fat diet. An earlier human study was conducted in Cameroon, as well.
"The mechanisms that presented themselves are not obvious and therefore are very patentable," states Dr. Denis Callewaert, a biotech consultant retained by Health Enhancement Products. "The isolated bioactive compounds derived from the ProAlgaZyme™ infusion are influencing the regulation of certain genetic functions and they are working in vivo, in living animals, not just in the laboratory. Typically, drug companies begin with synthetic compounds that might work with cells cultured in the laboratory. But, these compounds often fail when subsequently introduced into living organisms, whether mouse or human."