Researchers have new insight into the relationship between Parkinson's disease and smoking. Several studies have shown that smokers have a lower risk of developing Parkinson's disease. A new study published in the March 10, 2010, online issue of Neurology ®, the medical journal of the American Academy of Neurology, shows that smoking for a greater number of years may reduce the risk of the disease, but smoking a larger number of cigarettes per day may not reduce the risk.
"These results could guide the development of studies on various tobacco components with animal models to help understand the relationship between smoking and Parkinson's disease," said study author Honglei Chen, MD, PhD, of the National Institute of Environmental Health Sciences in Research Triangle Park, N.C. "Research to reveal the underlying chemicals and mechanisms is warranted; such studies may lead to a better understanding of the causes of Parkinson's disease. However, given the many adverse consequences of smoking, no one would suggest smoking in order to prevent Parkinson's disease."
The study involved 305,468 AARP members age 50 to 71 who completed a survey on diet and lifestyle at the time and again about 10 years later. During that time, 1,662 of the people had developed Parkinson's disease, or about one-half of one percent.
Current smokers were 44 percent less likely to develop Parkinson's disease than people who had never smoked. People who had smoked in the past and quit were 22 percent less likely to develop Parkinson's than people who had never smoked.