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ImmunoCellular Therapeutics receives Notice of Allowance covering antibodies targeting pancreatic cancer

Published on March 17, 2010 at 8:48 AM · No Comments

ImmunoCellular Therapeutics, Ltd. (OTCBB: IMUC), a biotechnology company that is developing immune based therapies for the treatment of various forms of cancer, announced today it received a Notice of Allowance from the United States Patent and Trademark Office covering technology relating to monoclonal antibodies that bind to certain epitopes present on pancreatic cancers. This patent will broaden the Company’s proprietary intellectual property for ICT-109 and ICT-37, two of the Company’s monoclonal antibody product candidates.

“The notice of allowance further strengthens ImmunoCellular’s intellectual property portfolio.”

ICT-109 and ICT-37 are humanized monoclonal antibodies that target small cell lung cancer and pancreatic cancer. ICT-109 antibody specifically binds to certain glycosylations (sugar structures) present on CEA-CAM6 and CEA-CAM5, which are highly expressed on malignant cells, while ICT-37 specifically targets CEA-CAM5.

“This is a very good news for us,” commented Dr. Manish Singh, PhD., President and CEO of IMUC. “The notice of allowance further strengthens ImmunoCellular’s intellectual property portfolio.” The Company also has 7 granted US patents and 8 issued international patents and over 25 pending patents.

In preclinical in-vitro testing, ICT-109 has been demonstrated to bind to 100% of pancreatic cancer tissues and has demonstrated an ability to detect the antigen in the blood sample of the patients. By combining ICT-109 with additional biomarkers, it may be possible to detect pancreatic cancer and lung cancers during their early stage, which usually results in longer survival times for those patients.

Source ImmunoCellular Therapeutics

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