NWBT announces release of new detailed report by Pharmaceuticals and Biotech Analyst

Northwest Biotherapeutics, Inc. ("NWBT") (OTC Bulletin Board: NWBO), developer of the DCVax® personalized cancer vaccine, today announced the release of a new detailed report by Pharmaceuticals and Biotech Analyst Dr. Navid Malik of the London-based Matrix Group.

As part of an in-depth review of the history and competitive landscape of what he calls the "cancer vaccine revolution," Dr. Malik concludes that "NWBT has generated some of the most striking data on survival and delayed time to progression in both brain cancer and prostate cancer that we have seen from any product in the market or in clinical development." Citing both "high dendritic cell purity" and "the single-batch bulk manufacturing process," as "key advantages of NWBT's technology which have not yet been appreciated by the market," he concludes that this gives DCVax® a "competitive advantage…versus virtually all of the other personalized cancer vaccine players."

A brief summary of the key findings in Dr. Malik's 40 page Report is attached, and upon your request we can send you by email or otherwise the 1 MB PDF file of the full text of the Report, with all of the supporting analysis.

Linda Powers, Chairman of the Board of NWBT stated "We are grateful to Matrix for undertaking such a comprehensive analytical review of the increasingly active and promising cancer vaccine field. We are gratified that their conclusions support what NWBT has worked to achieve over the last 10 years: compelling late stage clinical trial results at major institutions for several different cancers."

Looking to the future, Powers continued, "Now it is up to us to take what we have accomplished, spread the word, and execute on the competitive and medical promise which Matrix has identified. With the tremendous unmet worldwide need for better cancer treatments – ones that are non-toxic, more effective and less costly -- immune therapies are well equipped to meet that challenge."

Other key conclusions from Dr. Malik's newly released Report include:

• The survival data seen to date with the NWBT technology in prostate cancer has been exceptional. While Dendreon's Provenge has demonstrated a median survival in pivotal trials of 25.9 months, NWBT's DCVax®-Prostate has demonstrated median survival in Phase I/II studies of 38.7 months, with 64% of patients surviving at three years (Provenge three year survival: 34%). DCVax®-Prostate has been cleared by FDA to begin a US Phase Ill clinical trial.
• In Glioblastoma multiforme (GBM), the survival rates in trials with NWBT's DCVax® thus far have been highly impressive - earlier Phase I and Phase I/Il trials have demonstrated a median survival of 36.4 months versus 14.6 months with standard of care (including surgery, radiation and chemotherapy with Temodar). What is particularly significant is the fact that over 68% of patients live beyond two years compared to 27.2% seen with standard of care.
• If DCVax®-Brain and DCVax®-Prostate are successful in their respective pivotal trials and eventually approved, then we see both products as having potential blockbuster sales. More importantly there are other key advantages to NWBT's technology which have not yet been appreciated by the market. This includes clear manufacturing advantages offered by NWBTs single-batch bulk manufacturing process (which will be automated in the future using a proprietary, patent protected manufacturing process), and by its high dendritic cell purity of the final vaccine and crucially what we believe is a stronger patent position for DCVax®-Prostate than for Provenge outside of the US.