Results of the largest U.S. outpatient heart failure clinical study show that implementation of a process improvement program significantly improved adherence to evidence-based, guideline-recommended cardiac resynchronization therapy (CRT), implantable cardioverter-defibrillator (ICD) and drug therapy. Twenty-four-month findings from IMPROVE HF, (The Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting), were made available online and will be formally published in the August 10 issue of Circulation: Journal of the American Heart Association. This study was funded by Medtronic, Inc. (NYSE: MDT).
“Medtronic is committed to supporting research and providing solutions that will help physicians provide better quality of care for their heart failure patients”
The study demonstrates that cardiology practices implementing the process improvement program significantly increased use on five of seven guideline-recommended care measures. Specifically, CRT and ICD use increased by 30 and 27 percent, respectively, and aldosterone antagonist use increased by 25 percent, all compared to baseline results. The study also showed significant improvement on use of beta blockers and the delivery of heart failure education when practice improvement programs were implemented. Use of angiotensin converting enzyme inhibitors or angiotensin II receptor blockers and anticoagulation for atrial fibrillation did not show significant improvement.
"With more than five million Americans suffering from heart failure and as one of the few cardiovascular diseases on the rise, there is a clear and urgent need to close the treatment gap between heart failure guidelines and the level of care patients currently receive," said Gregg C. Fonarow, M.D., co-chair of the IMPROVE HF Scientific Steering Committee and Professor of Cardiovascular Medicine at the University of California at Los Angeles. "The IMPROVE HF study results serve as a call to action to transform heart failure care delivery in the outpatient practice setting to consistently implement guideline-driven standards of care."