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XARELTO achieves net clinical benefit in treatment of patients with DVT

Published on September 2, 2010 at 7:07 AM · No Comments

The EINSTEIN-DVT study reinforces that XARELTO is a simple and convenient treatment option for clinicians and patients alike

Bayer HealthCare Pharmaceuticals today announced that XARELTO(R) (rivaroxaban), a novel anti-clotting therapy, achieved improvement in net clinical benefit in a study looking at treatment of patients with deep vein thrombosis (DVT). DVT is the formation of a blood clot in a deep vein, usually in the legs, that partially or totally blocks the flow of blood. It is estimated that DVT affects 45,000 Canadians per year. Around one-third of patients with DVT will progress to having a potentially fatal pulmonary embolism (PE), where the blood clot breaks apart and travels to the lungs, ultimately blocking a blood vessel there. Even in the absence of a PE, DVT alone can have burdensome and costly consequences such as post-thrombotic syndrome and an increased risk of recurring blood clots. Therefore, achieving treatment goals is essential. XARELTO prevents the formation and minimizes the risk of these potentially-deadly blood clots.

"Results from this study could change the way doctors treat deep vein thrombosis," says Dr. Alexander G. G. Turpie, Professor of Medicine at the Michael G. DeGroote School of Medicine at McMaster University, Hamilton, ON. "A single-drug approach such as XARELTO could potentially provide an effective and well-tolerated DVT treatment for clinicians to prescribe, as well as a convenient, fixed-dose regimen for patients to use."

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