Negotiators from the United States and 10 other countries last month concluded a 14th round of private talks in Leesburg, Va., "to wrap up the Trans-Pacific Partnership, poised to become the largest trade deal in U.S. history," the Charlotte Observer reports. The talks "involve a tussle over how far to go to protect intellectual property rights and, with them, the finances of brand-name drug companies," according to the newspaper, which adds, "If drug companies get their way in protecting brand-name drugs in a new international trade deal, critics say, millions of AIDS patients in poor countries will go untreated, losing access to cheaper generic drugs that could keep them alive."