New partnership to make advancements in personalized breast cancer treatment and care

Published on November 3, 2012 at 2:25 AM · No Comments

The Edith Sanford Breast Cancer Foundation and The Scripps Research Institute (TSRI) today announced the formation of a dynamic partnership that will lay the groundwork for lifesaving advancements in personalized breast cancer treatment and care.

Edith Sanford Breast Cancer Research will leverage TSRI's expertise in genomic sequencing as it embarks on a defining study to compare the genes of a woman's healthy cells with her breast tumor cells in an effort to more precisely understand the changes that cause breast cancer to develop and progress.

"Edith Sanford is thrilled to partner with Scripps Research, an institution that is on the cutting-edge of genomics, and harness their expertise and technological capabilities in our work to accelerate these discoveries from the bench to bedside," said Brian Leyland Jones, MB BS, PhD, director of Edith Sanford Breast Cancer Research. "This partnership will facilitate the translation of large-scale sequencing data into meaningful information that will help us understand how to more precisely and accurately treat breast cancer patients based on their DNA profiles."

Specifically, Edith Sanford will provide tissue samples from 25 women with breast cancer to TSRI for analysis to identify the changes in genes and proteins that are linked to the cancer, and Edith Sanford will then validate findings through clinical testing. The principal objective of this study is to establish research protocols that will guide Edith Sanford in launching ambitious larger-scale projects that will help pioneer the integration of genomics into breast cancer research and patient care.

"We are committed to helping accelerate the work of Edith Sanford to bring to patients the lifesaving potential of forward genomic research," said Brandon Young, director of the Genomics and Cell-Based Screening Core Lab at Scripps Florida. "We are excited to work with Edith Sanford as it establishes a genomics program that will transform the way we think about and treat breast cancer."

Young and colleagues, Nicholas Schork, PhD, Ali Torkamani, PhD, and Andrew Su, PhD, at Scripps California, and the Genomics Core at Scripps Florida will be working jointly with the research team at Edith Sanford.

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