New protein microarray kit is designed to aid researchers in lead discovery
Kinexus Bioinformatics Corporation, a world leader in functional proteomics research, announced today the release of its first KinexTM antibody microarray kit with its latest generation KAM-850 chip. The new antibody microarray is capable of tracking the levels and functional states of hundreds of diverse proteins in human and animal cell and tissue specimens and features more than 330 phosphosite- and 540 pan-specific antibody probes. This provides researchers with a reliable proteomics tool to study changes in cell signaling proteins that occur in response to a range of treatments, drugs, toxins, pathological and other experimental conditions. The KAM-850 chip now provides for the broadest coverage of protein kinase and protein phosphatases targets and their regulatory phosphorylation sites in the market place today with the lowest costs, about US 20¢ per antibody measurement. The purchase costs of commercial antibodies range from 200 to 300 US$ each, so the Kinex™ antibody microarray format offers incredible economy to enable researchers to better identify novel biomarkers for disease diagnostics purposes and for the discovery of new research leads.
"By offering the most affordable and highest quality antibody microarrays, we enable scientists to conduct proteome-wide screening in their own laboratories to further advance signal transduction research that will ultimately help improve patient care", said Dr. Steven Pelech, President and founder of Kinexus and a professor in the Division of Neurology at the University of British Columbia. "We have already used our KinexTM antibody microarray to successfully identify panels of candidate biomarkers for Alzheimer's disease and ALS that we are hoping to develop as diagnostic targets."